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Digital Breast Tomosynthesis (DBT) enhances finding visibility for breast cancer detection by providing volumetric information that reduces the impact of overlapping tissues; however, limited annotated data has constrained the development…
Ultrasound is a widely accessible and cost-effective medical imaging tool commonly used for prenatal evaluation of the fetal brain. However, it has limitations, particularly in the third trimester, where the complexity of the fetal brain…
Cerebral aneurysms and arteriovenous malformations are life-threatening hemodynamic pathologies of the brain. While surgical intervention is often essential to prevent fatal outcomes, it carries significant risks both during the procedure…
The biological definition of Alzheimer's disease (AD) relies on multi-modal neuroimaging, yet the clinical utility of positron emission tomography (PET) is limited by cost and radiation exposure, hindering early screening at preclinical or…
4D Flow Magnetic Resonance Imaging (4D Flow MRI) is a non-invasive measurement technique capable of quantifying blood flow across the cardiovascular system. While practical use is limited by spatial resolution and image noise, incorporation…
Accurate visualization of interventional devices, such as medical needles, is essential for the safe and effective guidance of minimally invasive procedures. Ultrasound (US) imaging is widely used for needle guidance, but the…
Early infancy is a rapid and dynamic neurodevelopmental period for behavior and neurocognition. Longitudinal magnetic resonance imaging (MRI) is an effective tool to investigate such a crucial stage by capturing the developmental…
Automatic blood vessel extraction from 3D medical images is crucial for vascular disease diagnoses. Existing methods based on convolutional neural networks (CNNs) may suffer from discontinuities of extracted vessels when segmenting such…
Row-Column Arrays (RCAs) offer an attractive alternative to fully wired 2D-arrays for 3D-ultrasound, due to their greatly simplified wiring. However, conventional RCAs face challenges related to their long elements. These include an…
In this paper, we develop a 2D and 3D segmentation pipelines for fully automated cardiac MR image segmentation using Deep Convolutional Neural Networks (CNN). Our models are trained end-to-end from scratch using the ACD Challenge 2017…
Computational ultrasound imaging (cUSi) with few elements and spatial field encoding can provide high-resolution volumetric B-mode imaging. In this work, we extend its application to 4D carotid artery (CA) flow imaging using a custom…
Accurate analysis of cardiac motion is crucial for evaluating cardiac function. While dynamic cardiac magnetic resonance imaging (CMR) can capture detailed tissue motion throughout the cardiac cycle, the fine-grained 4D cardiac motion…
Noninvasive imaging deep into the adult brain at submillimeter and millisecond scales remains a challenge in medical imaging. Here, we report a helmet based ultrasound brain imager built from a customized helmet, a scanned ultrasound array,…
Background: Conventional cardiovascular magnetic resonance (CMR) in paediatric and congenital heart disease uses 2D, breath-hold, balanced steady state free precession (bSSFP) cine imaging for assessment of function and cardiac-gated,…
We propose an ultrasound approach which provides, with one single examination and one single device, access to three bone biomarkers: anatomy, tissue quality and blood flow. It unlocks ultrasound imaging inside bone by accounting for…
Understanding how networks of neurons process information is one of the key challenges in modern neuroscience. A necessary step to achieve this goal is to be able to observe the dynamics of large populations of neurons over a large area of…
Magnetic Resonance (MR) imaging plays an essential role in contemporary clinical diagnostics. It is increasingly integrated into advanced therapeutic workflows, such as hybrid Positron Emission Tomography/Magnetic Resonance (PET/MR) imaging…
The regulation of intestinal blood flow is critical to gastrointestinal function. Imaging the intestinal mucosal micro-circulation in vivo has the potential to provide new insight into the gut physiology and pathophysiology. We aimed to…
Late gadolinium enhancement (LGE) cardiac MRI (CMR) is the clinical standard for diagnosis of myocardial scar. 3D isotropic LGE CMR provides improved coverage and resolution compared to 2D imaging. However, image acceleration is required…
Four-dimensional Flow MRI enables non-invasive, time-resolved imaging of blood flow in three spatial dimensions, offering valuable insights into complex hemodynamics. However, its clinical utility is limited by low spatial resolution and…