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Statistical analysis of magnetic resonance imaging (MRI) can help radiologists to detect pathologies that are otherwise likely to be missed. Deep learning (DL) has shown promise in modeling complex spatial data for brain anomaly detection.…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Victor Saase , Holger Wenz , Thomas Ganslandt , Christoph Groden , Máté E. Maros

Significance: Cerebral blood flow (CBF) imaging is crucial for diagnosing cerebrovascular diseases. However, existing large neuroimaging techniques with high cost, low sampling rate, and poor mobility make them unsuitable for continuous and…

Tissues and Organs · Quantitative Biology 2024-08-26 Faezeh Akbari , Xuhui Liu , Fatemeh Hamedi , Mehrana Mohtasebi , Lei Chen , Guoqiang Yu

Cerebrovascular diseases such as brain aneurysms are a primary cause of adult disability. The flow dynamics in brain arteries, both during periods of rest and increased activity, are known to be a major factor in the risk of aneurysm…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-04-30 Mohamed A. Itani , Ulf D. Schiller , Sebastian Schmieschek , James Hetherington , Miguel O. Bernabeu , Hoskote Chandrashekar , Fergus Robertson , Peter V. Coveney , Derek Groen

Magnetic resonance imaging (MRI) provides high spatial resolution and excellent soft-tissue contrast without using harmful ionising radiation. Dynamic MRI is an essential tool for interventions to visualise movements or changes of the…

Medical Physics · Physics 2022-02-14 Soumick Chatterjee , Chompunuch Sarasaen , Georg Rose , Andreas Nürnberger , Oliver Speck

Ultrasound (US) can be used to assess brain development in newborns, as MRI is challenging due to immobilization issues, and may require sedation. Dilatation of the lateral ventricles in the brain is a risk factor for poorer…

Computer Vision and Pattern Recognition · Computer Science 2018-06-07 Marc-Antoine Boucher , Sarah Lippe , Amelie Damphousse , Ramy El-Jalbout , Samuel Kadoury

Vascular networks play a crucial role in understanding brain functionalities. Brain integrity and function, neuronal activity and plasticity, which are crucial for learning, are actively modulated by their local environments, specifically…

Neurons and Cognition · Quantitative Biology 2024-02-28 Jiachen Yao , Nina Hagemann , Qiaojie Xiong , Jianxu Chen , Dirk M. Hermann , Chao Chen

Background: This protocol introduces an ultrasound (US) configuration for whole-body 3D dynamic contrast-enhanced ultrasound (DCE-US) imaging in preclinical applications. The set-up relies on a clinical abdominal matrix US probe to enable…

Synchrotron radiation-based X-ray microtomography is uniquely suited for post mortem three-dimensional visualization of organs such as the mouse brain. Tomographic imaging of the entire mouse brain with isotropic cellular resolution…

In this paper, we are concerned with the simulation of blood flow in microvascular networks and the surrounding tissue. To reduce the computational complexity of this issue, the network structures are modeled by a one-dimensional graph,…

Numerical Analysis · Mathematics 2023-05-01 Ettore Vidotto , Timo Koch , Tobias Köppl , Rainer Helmig , Barbara Wohlmuth

Morphology of cardiovascular tissue is influenced by the unsteady behavior of the blood flow and vice versa. Therefore, the pathogenesis of several cardiovascular diseases is directly affected by the blood-flow dynamics. Understanding flow…

Angiogenesis, the formation of new vessels, is one of the key mechanisms in tumor development and an appealing target for therapy. Non-invasive, high-resolution, high sensitivity, quantitative 3D imaging techniques are required to correctly…

Image and Video Processing · Electrical Eng. & Systems 2019-12-06 Charlie Demené , Thomas Payen , Alexandre Dizeux , Guillaume Barrois , Jean-Luc Gennisson , Lori Bridal , Mickael Tanter

Assessing the location and extent of lesions caused by chronic stroke is critical for medical diagnosis, surgical planning, and prognosis. In recent years, with the rapid development of 2D and 3D convolutional neural networks (CNN), the…

Image and Video Processing · Electrical Eng. & Systems 2021-02-17 Yongjin Zhou , Weijian Huang , Pei Dong , Yong Xia , Shanshan Wang

The rapid increase in the number of Computed Tomography (CT) scan examinations has created an urgent need for automated tools, such as organ segmentation, anomaly classification, and report generation, to assist radiologists with their…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Theo Di Piazza , Carole Lazarus , Olivier Nempont , Loic Boussel

Time-resolved three-dimensional flow MRI (4D flow MRI) provides a unique non-invasive solution to visualize and quantify hemodynamics in blood vessels such as the aortic arch. However, most current analysis methods for arterial 4D flow MRI…

Computer Vision and Pattern Recognition · Computer Science 2024-07-31 Simone Garzia , Patryk Rygiel , Sven Dummer , Filippo Cademartiri , Simona Celi , Jelmer M. Wolterink

Three-dimensional ultrasound (US) offers many clinical advantages over conventional 2D imaging, yet its widespread adoption is limited by the cost and complexity of traditional 3D systems. Sensorless 3D US, which uses deep learning to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Paul F. R. Wilson , Matteo Ronchetti , Rüdiger Göbl , Viktoria Markova , Sebastian Rosenzweig , Raphael Prevost , Parvin Mousavi , Oliver Zettinig

The objective of this study is to develop a deep-learning based detection and diagnosis technique for carotid atherosclerosis using a portable freehand 3D ultrasound (US) imaging system. A total of 127 3D carotid artery scans were acquired…

Image and Video Processing · Electrical Eng. & Systems 2023-11-10 Jiawen Li , Yunqian Huang , Sheng Song , Hongbo Chen , Junni Shi , Duo Xu , Haibin Zhang , Man Chen , Rui Zheng

Unprecedented visual details of biological structures are being revealed by subcellular-resolution whole-brain 3D microscopy data, enabled by recent advances in intact tissue processing and light-sheet fluorescence microscopy (LSFM). These…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Minyoung E. Kim , Dae Hee Yun , Aditi V. Patel , Madeline Hon , Webster Guan , Taegeon Lee , Brian Nguyen

Top-Orthogonal-to-Bottom-Electrode (TOBE) arrays, also known as bias-switchable row-column arrays (RCAs), allow for imaging techniques otherwise impossible for non-bias-switachable RCAs. Hadamard Encoded Row Column Ultrasonic Expansive…

Image and Video Processing · Electrical Eng. & Systems 2025-09-15 Darren Olufemi Dahunsi , Randy Palmar , Tyler Henry , Mohammad Rahim Sobhani , Negar Majidi , Joy Wang , Afshin Kashani Ilkhechi , Jeremy Brown , Roger Zemp

Diffuse correlation spectroscopy (DCS) analyzes the autocorrelation function of photons scattered by red blood cells, enabling non-invasive, continuous measurement of deep tissue blood flow at the bedside. Multi-layer DCS models (two- and…

Brain atrophy is an important biomarker for monitoring neurodegeneration and disease progression in conditions such as multiple sclerosis (MS). An accurate and robust quantitative measurement of brain volume change is paramount for…

Quantitative Methods · Quantitative Biology 2023-02-09 Geng Zhan , Dongang Wang , Mariano Cabezas , Lei Bai , Kain Kyle , Wanli Ouyang , Michael Barnett , Chenyu Wang
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