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Gradients of probabilistic model likelihoods with respect to their parameters are essential for modern computational statistics and machine learning. These calculations are readily available for arbitrary models via automatic…

Populations and Evolution · Quantitative Biology 2023-06-06 Mathieu Fourment , Christiaan J. Swanepoel , Jared G. Galloway , Xiang Ji , Karthik Gangavarapu , Marc A. Suchard , Frederick A. Matsen

Phylogenetics begins with reconstructing biological family trees from genetic data. Since Nature is not limited to tree-like histories, we use networks to organize our data, and have discovered new polytopes, metric spaces, and simplicial…

Combinatorics · Mathematics 2019-05-28 Satyan Devadoss , Cassandra Durell , Stefan Forcey

In this note, we consider a complete intersection $X=\{x\in \mathbb{R}^n : f_1(x)= \ldots = f_m(x)=0\}, n>m$ and study its Euclidean distance degree in terms of the mixed volume of the Newton polytopes. We show that if the Newton polytopes…

Algebraic Geometry · Mathematics 2024-05-03 Nguyen Tat Thang , Pham Thu Thuy

Phylogenetic trees and networks are leaf-labelled graphs that are used to describe evolutionary histories of species. The Tree Containment problem asks whether a given phylogenetic tree is embedded in a given phylogenetic network. Given a…

Populations and Evolution · Quantitative Biology 2010-06-17 Leo van Iersel , Charles Semple , Mike Steel

Ultrametric matrices are a class of covariance matrices that arise in latent tree models. As a parameter space in a statistical model, the set of ultrametric matrices is neither convex nor a smooth manifold. Focus in the literature has…

Methodology · Statistics 2025-04-28 Tsung-Hung Yao , Zhenke Wu , Karthik Bharath , Veerabhadran Baladandayuthapani

It is generally accepted that "diversity" is associated with success in evolutionary algorithms. However, diversity is a broad concept that can be measured and defined in a multitude of ways. To date, most evolutionary computation research…

Neural and Evolutionary Computing · Computer Science 2023-01-18 Jose Guadalupe Hernandez , Alexander Lalejini , Emily Dolson

Binary phylogenetic trees inferred from biological data are central to understanding the shared history among evolutionary units. However, inferring the placement of latent nodes in a tree is computationally expensive. State-of-the-art…

Populations and Evolution · Quantitative Biology 2025-03-26 Matthew J Penn , Neil Scheidwasser , Mark P Khurana , David A Duchêne , Christl A Donnelly , Samir Bhatt

In this article we introduce a new family of lattice polytopes with rational linear precision. For this purpose, we define a new class of discrete statistical models that we call multinomial staged tree models. We prove that these models…

Combinatorics · Mathematics 2022-08-10 Isobel Davies , Eliana Duarte , Irem Portakal , Miruna-Stefana Sorea

The phylogenetic tree space introduced by Billera, Holmes, and Vogtmann (BHV tree space) is a CAT(0) continuous space that represents trees with edge weights with an intrinsic geodesic distance measure. The geodesic distance measure unique…

Quantitative Methods · Quantitative Biology 2021-10-29 Yingying Ren , Sihan Zha , Jingwen Bi , José A. Sanchez , Cara Monical , Michelle Delcourt , Rosemary K. Guzman , Ruth Davidson

We study a class of complex polynomial equations on a finite graph with a view to understanding how holistic phenomena emerge from combinatorial structure. Particular solutions arise from orthogonal projections of regular polytopes,…

Mathematical Physics · Physics 2011-09-16 Paul Baird

One approach to estimating a species tree from a collection of gene trees is to first estimate probabilities of clades from the gene trees, and then to construct the species tree from the estimated clade probabilities. While a greedy…

Populations and Evolution · Quantitative Biology 2012-11-14 Elizabeth S. Allman , James H. Degnan , John A. Rhodes

Phylogenetic diversity indices are commonly used to rank the elements in a collection of species or populations for conservation purposes. The derivation of these indices is typically based on some quantitative description of the…

Populations and Evolution · Quantitative Biology 2024-03-26 Vincent Moulton , Andreas Spillner , Kristina Wicke

The statistical estimation of phylogenies is always associated with uncertainty, and accommodating this uncertainty is an important component of modern phylogenetic comparative analysis. The birth-death polytomy resolver is a method of…

Quantitative Methods · Quantitative Biology 2015-03-18 Daniel L. Rabosky

We study the fundamental question of how likely it is that two randomly chosen trees are isomorphic to each other for different models of random trees. We show that the probability decays exponentially for rooted labeled trees as well as…

Probability · Mathematics 2023-04-11 Christoffer Olsson

Phylogenetic networks are an important way to represent evolutionary histories that involve reticulations such as hybridization or horizontal gene transfer, yet fundamental questions such as how many networks there are that satisfy certain…

Populations and Evolution · Quantitative Biology 2025-02-21 Andrew Francis , Michael Hendriksen

For finite q, we classify the countable, descendant-homogeneous digraphs in which the descendant set of any vertex is a q-valent tree. We also give conditions on a rooted digraph G which allow us to construct a countable…

Combinatorics · Mathematics 2011-04-08 Daniela Amato , David M. Evans , John K. Truss

The reconstruction of phylogenies from DNA or protein sequences is a major task of computational evolutionary biology. Common phenomena, notably variations in mutation rates across genomes and incongruences between gene lineage histories,…

Probability · Mathematics 2012-11-30 Elchanan Mossel , Sebastien Roch

Phylogenetic inference-the derivation of a hypothesis for the common evolutionary history of a group of species- is an active area of research at the intersection of biology, computer science, mathematics, and statistics. One assumes the…

Populations and Evolution · Quantitative Biology 2016-06-21 Ruth Davidson , Joseph Rusinko , Zoe Vernon , Jing Xi

The notions of convexity and convex polytopes are introduced in the setting of tropical geometry. Combinatorial types of tropical polytopes are shown to be in bijection with regular triangulations of products of two simplices. Applications…

Metric Geometry · Mathematics 2007-05-23 Mike Develin , Bernd Sturmfels

Species tree estimation is a complex problem, due to the fact that different parts of the genome can have different evolutionary histories than the genome itself. One of the causes for this discord is incomplete lineage sorting (also called…

Populations and Evolution · Quantitative Biology 2019-04-09 Erin Molloy , Tandy Warnow
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