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In clinical practice, crossmodal information including medical images and tabular data is essential for disease diagnosis. There exists a significant modality gap between these data types, which obstructs advancements in crossmodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Tianling Liu , Hongying Liu , Fanhua Shang , Lequan Yu , Tong Han , Liang Wan

We suggest and implement an approach for the bottom-up description of systems undergoing large-scale structural changes and chemical transformations from dynamic atomically resolved imaging data, where only partial or uncertain data on…

Materials Science · Physics 2021-04-23 Sergei V. Kalinin , Ondrej Dyck , Stephen Jesse , Maxim Ziatdinov

Temporal modeling in complex systems requires capturing dependencies across multiple time scales while managing inherent uncertainties. We propose HierCVAE, a novel architecture that integrates hierarchical attention mechanisms with…

Machine Learning · Computer Science 2025-08-27 Yao Wu

The remarkable success of foundation models has sparked growing interest in their application to single-cell biology. Models like Geneformer and scGPT promise to serve as versatile tools in this specialized field. However, representing a…

Quantitative Methods · Quantitative Biology 2024-11-12 Jiabei Cheng , Jiachen Li , Kaiyuan Yang , Hongbin Shen , Ye Yuan

We investigate deep generative models that can exchange multiple modalities bi-directionally, e.g., generating images from corresponding texts and vice versa. Recently, some studies handle multiple modalities on deep generative models, such…

Machine Learning · Statistics 2016-11-08 Masahiro Suzuki , Kotaro Nakayama , Yutaka Matsuo

Handling missing data remains a fundamental challenge in real-world tabular datasets, especially when data are heterogeneous with both numerical and categorical features. Existing imputation methods often fail to capture complex structural…

Machine Learning · Computer Science 2025-12-01 Youran Zhou , Mohamed Reda Bouadjenek , Sunil Aryal%

Existing image generation models face critical challenges regarding the trade-off between computation and fidelity. Specifically, models relying on a pretrained Variational Autoencoder (VAE) suffer from information loss, limited detail, and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Chenrui Ma , Xi Xiao , Tianyang Wang , Xiao Wang , Yanning Shen

Parameterized mathematical models play a central role in understanding and design of complex information systems. However, they often cannot take into account the intricate interactions innate to such systems. On the contrary, purely…

Signal Processing · Electrical Eng. & Systems 2019-12-02 Shahin Khobahi , Mojtaba Soltanalian

Deep learning has empowered analysis for single-cell sequencing data in many ways and has generated deep understanding about a range of complex cellular systems. As the booming single-cell sequencing technologies brings the surge of high…

Genomics · Quantitative Biology 2021-04-27 Yang Xu , Andrew Jeremiah Strick

Due to the superiority in similarity computation and database storage for large-scale multiple modalities data, cross-modal hashing methods have attracted extensive attention in similarity retrieval across the heterogeneous modalities.…

Information Retrieval · Computer Science 2020-01-15 Lu Wang , Jie Yang

Graphs are ubiquitous data structures for representing interactions between entities. With an emphasis on the use of graphs to represent chemical molecules, we explore the task of learning to generate graphs that conform to a distribution…

Machine Learning · Computer Science 2019-03-08 Qi Liu , Miltiadis Allamanis , Marc Brockschmidt , Alexander L. Gaunt

Learning from multiple sources of information is an important problem in machine-learning research. The key challenges are learning representations and formulating inference methods that take into account the complementarity and redundancy…

Machine Learning · Statistics 2018-11-20 Richard Kurle , Stephan Günnemann , Patrick van der Smagt

Identifying species in biology among tens of thousands of visually similar taxa while discovering unknown species in open-world environments remains a fundamental challenge in biodiversity research. Current methods treat identification and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Jiawei Wang , Ming Lei , Yaning Yang , Xinyan Lin , Yuquan Le , Qiwei Ma , Zhiwei Xu , Zheqi Lv , Yuchen Ang , Zhe Quan , Tat-Seng Chua

The recently developed variational autoencoders (VAEs) have proved to be an effective confluence of the rich representational power of neural networks with Bayesian methods. However, most work on VAEs use a rather simple prior over the…

Machine Learning · Computer Science 2017-08-29 Prasoon Goyal , Zhiting Hu , Xiaodan Liang , Chenyu Wang , Eric Xing

The framework of variational autoencoders allows us to efficiently learn deep latent-variable models, such that the model's marginal distribution over observed variables fits the data. Often, we're interested in going a step further, and…

Machine Learning · Statistics 2020-12-22 Ilyes Khemakhem , Diederik P. Kingma , Ricardo Pio Monti , Aapo Hyvärinen

Single-cell RNA sequencing (scRNA-seq) data analysis is pivotal for understanding cellular heterogeneity. However, the high sparsity and complex noise patterns inherent in scRNA-seq data present significant challenges for traditional…

Genomics · Quantitative Biology 2024-08-13 Wenwen Min , Zhen Wang , Fangfang Zhu , Taosheng Xu , Shunfang Wang

Accurately predicting the survival rate of cancer patients is crucial for aiding clinicians in planning appropriate treatment, reducing cancer-related medical expenses, and significantly enhancing patients' quality of life. Multimodal…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Liangrui Pan , Yijun Peng , Yan Li , Xiang Wang , Wenjuan Liu , Liwen Xu , Qingchun Liang , Shaoliang Peng

This work studies the problem of modeling visual processes by leveraging deep generative architectures for learning linear, Gaussian representations from observed sequences. We propose a joint learning framework, combining a vector…

Neural and Evolutionary Computing · Computer Science 2020-04-13 Alexander Sagel , Hao Shen

We propose Variational Heteroscedastic Volatility Model (VHVM) -- an end-to-end neural network architecture capable of modelling heteroscedastic behaviour in multivariate financial time series. VHVM leverages recent advances in several…

Statistical Finance · Quantitative Finance 2022-04-13 Zexuan Yin , Paolo Barucca

Multimodal learning is a framework for building models that make predictions based on different types of modalities. Important challenges in multimodal learning are the inference of shared representations from arbitrary modalities and…

Machine Learning · Computer Science 2022-07-06 Masahiro Suzuki , Yutaka Matsuo
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