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As LLM-based agents operate over sequential multi-step reasoning, hallucinations arising at intermediate steps risk propagating along the trajectory, thus degrading overall reliability. Unlike hallucination detection in single-turn…

Computation and Language · Computer Science 2026-01-13 Xuannan Liu , Xiao Yang , Zekun Li , Peipei Li , Ran He

Large Language Models (LLMs) are widely used in industry but remain prone to hallucinations, limiting their reliability in critical applications. This work addresses hallucination reduction in consumer grievance chatbots built using LLaMA…

In the current digital era, the rapid spread of misinformation on online platforms presents significant challenges to societal well-being, public trust, and democratic processes, influencing critical decision making and public opinion. To…

Computation and Language · Computer Science 2024-05-06 Xinyi Li , Yongfeng Zhang , Edward C. Malthouse

The integration of deep learning-based glaucoma detection with large language models (LLMs) presents an automated strategy to mitigate ophthalmologist shortages and improve clinical reporting efficiency. However, applying general LLMs to…

Multiagent Systems · Computer Science 2025-12-18 Philip R. Liu , Sparsh Bansal , Jimmy Dinh , Aditya Pawar , Ramani Satishkumar , Shail Desai , Neeraj Gupta , Xin Wang , Shu Hu

While large language models (LLMs) have been successfully applied to various tasks, they still face challenges with hallucinations. Augmenting LLMs with domain-specific tools such as database utilities can facilitate easier and more precise…

Computation and Language · Computer Science 2024-04-10 Qiao Jin , Yifan Yang , Qingyu Chen , Zhiyong Lu

A common and fundamental limitation of Generative AI (GenAI) is its propensity to hallucinate. While large language models (LLM) have taken the world by storm, without eliminating or at least reducing hallucinations, real-world GenAI…

Machine Learning · Computer Science 2024-12-03 Patrice Béchard , Orlando Marquez Ayala

Pharmaceutical patents play a vital role in biochemical industries, especially in drug discovery, providing researchers with unique early access to data, experimental results, and research insights. With the advancement of machine learning,…

Machine Learning · Computer Science 2024-10-30 Xin Wang , Yifan Zhang , Xiaojing Zhang , Longhui Yu , Xinna Lin , Jindong Jiang , Bin Ma , Kaicheng Yu

Empowered by large language models (LLMs), intelligent agents have become a popular paradigm for interacting with open environments to facilitate AI deployment. However, hallucinations generated by LLMs-where outputs are inconsistent with…

Machine Learning · Computer Science 2025-07-23 Siyuan Liu , Wenjing Liu , Zhiwei Xu , Xin Wang , Bo Chen , Tao Li

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

The advancements of large language models (LLMs) have piqued growing interest in developing LLM-based language agents to automate scientific discovery end-to-end, which has sparked both excitement and skepticism about their true…

Large Language Model (LLM) Agents have demonstrated remarkable capabilities in task automation and intelligent decision-making, driving the widespread adoption of agent development frameworks such as LangChain and AutoGen. However, these…

Artificial Intelligence · Computer Science 2025-10-10 Jiabin Tang , Tianyu Fan , Chao Huang

Open-sourced Large Language Models (LLMs) have achieved great success in various NLP tasks, however, they are still far inferior to API-based models when acting as agents. How to integrate agent ability into general LLMs becomes a crucial…

Computation and Language · Computer Science 2024-03-20 Zehui Chen , Kuikun Liu , Qiuchen Wang , Wenwei Zhang , Jiangning Liu , Dahua Lin , Kai Chen , Feng Zhao

We present Genie-CAT, a tool-augmented large-language-model (LLM) system designed to accelerate scientific hypothesis generation in protein design. Using metalloproteins (e.g., ferredoxins) as a case study, Genie-CAT integrates four…

Quantitative Methods · Quantitative Biology 2025-11-25 Bruno Jacob , Khushbu Agarwal , Marcel Baer , Peter Rice , Simone Raugei

Large language models demonstrate remarkable reasoning capabilities but often produce unreliable or incorrect responses. Existing verification methods are typically model-specific or domain-restricted, requiring significant computational…

Computation and Language · Computer Science 2025-08-22 Jiuzhou Han , Wray Buntine , Ehsan Shareghi

Large Language Model (LLM)-based agents have recently shown impressive capabilities in complex reasoning and tool use via multi-step interactions with their environments. While these agents have the potential to tackle complicated tasks,…

Artificial Intelligence · Computer Science 2025-11-04 Jiaye Lin , Yifu Guo , Yuzhen Han , Sen Hu , Ziyi Ni , Licheng Wang , Mingguang Chen , Hongzhang Liu , Ronghao Chen , Yangfan He , Daxin Jiang , Binxing Jiao , Chen Hu , Huacan Wang

The prevalent use of large language models (LLMs) in various domains has drawn attention to the issue of "hallucination," which refers to instances where LLMs generate factually inaccurate or ungrounded information. Existing techniques for…

Computation and Language · Computer Science 2023-10-10 Junyu Luo , Cao Xiao , Fenglong Ma

We introduce GenAgent, unifying visual understanding and generation through an agentic multimodal model. Unlike unified models that face expensive training costs and understanding-generation trade-offs, GenAgent decouples these capabilities…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Kaixun Jiang , Yuzheng Wang , Junjie Zhou , Pandeng Li , Zhihang Liu , Chen-Wei Xie , Zhaoyu Chen , Yun Zheng , Wenqiang Zhang

Large language models (LLMs) have demonstrated significant reasoning capabilities in scientific discovery but struggle to bridge the gap to physical execution in wet-labs. In these irreversible environments, probabilistic hallucinations are…

Artificial Intelligence · Computer Science 2026-05-19 Yuyang Liu , Jingya Wang , Liuzhenghao Lv , Yonghong Tian

Large Vision-Language Models (LVLMs) have demonstrated strong reasoning capabilities in geo-localization, yet they often struggle in real-world scenarios where visual cues are sparse, long-tailed, and highly ambiguous. Previous approaches,…

Artificial Intelligence · Computer Science 2026-03-03 Furong Jia , Ling Dai , Wenjin Deng , Fan Zhang , Chen Hu , Daxin Jiang , Yu Liu

Despite the many advances of Large Language Models (LLMs) and their unprecedented rapid evolution, their impact and integration into every facet of our daily lives is limited due to various reasons. One critical factor hindering their…

Computation and Language · Computer Science 2024-08-20 Yakir Yehuda , Itzik Malkiel , Oren Barkan , Jonathan Weill , Royi Ronen , Noam Koenigstein