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Dermatological diagnosis requires integrating fine-grained visual perception with expert clinical knowledge. Although Multimodal Large Language Models (MLLMs) facilitate interactive medical image analysis, their application in dermatology…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Yize Liu , Siyuan Yan , Ming Hu , Lie Ju , Xieji Li , Feilong Tang , Wei Feng , Zongyuan Ge

Comprehending genomic information is essential for biomedical research, yet extracting data from complex distributed databases remains challenging. Large language models (LLMs) offer potential for genomic Question Answering (QA) but face…

Artificial Intelligence · Computer Science 2026-01-16 Kimia Abedini , Farzad Shami , Gianmaria Silvello

Large Language Models (LLMs) have demonstrated great potential in complex reasoning tasks, yet they fall short when tackling more sophisticated challenges, especially when interacting with environments through generating executable actions.…

Computation and Language · Computer Science 2025-02-25 Yuqi Zhu , Shuofei Qiao , Yixin Ou , Shumin Deng , Shiwei Lyu , Yue Shen , Lei Liang , Jinjie Gu , Huajun Chen , Ningyu Zhang

Hallucination detection is a challenging task for large language models (LLMs), and existing studies heavily rely on powerful closed-source LLMs such as GPT-4. In this paper, we propose an autonomous LLM-based agent framework, called…

Computation and Language · Computer Science 2024-06-18 Xiaoxue Cheng , Junyi Li , Wayne Xin Zhao , Hongzhi Zhang , Fuzheng Zhang , Di Zhang , Kun Gai , Ji-Rong Wen

Recent advancements in machine learning have significantly improved the identification of disease-associated genes from gene expression datasets. However, these processes often require extensive expertise and manual effort, limiting their…

Machine Learning · Computer Science 2025-04-09 Haoyang Liu , Shuyu Chen , Ye Zhang , Haohan Wang

Large-scale single-cell and Perturb-seq investigations routinely involve clustering cells and subsequently annotating each cluster with Gene-Ontology (GO) terms to elucidate the underlying biological programs. However, both stages,…

Recent advancements have highlighted that Large Language Models (LLMs) are prone to hallucinations when solving complex reasoning problems, leading to erroneous results. To tackle this issue, researchers incorporate Knowledge Graphs (KGs)…

Artificial Intelligence · Computer Science 2025-02-19 Ben Liu , Jihai Zhang , Fangquan Lin , Cheng Yang , Min Peng , Wotao Yin

Recent progress in Large Language Models (LLMs) has drawn attention to their potential for accelerating drug discovery. However, a central problem remains: translating theoretical ideas into robust implementations in the highly specialized…

Machine Learning · Computer Science 2025-03-06 Sizhe Liu , Yizhou Lu , Siyu Chen , Xiyang Hu , Jieyu Zhao , Yingzhou Lu , Yue Zhao

Agents based on large language models have shown great potential in accelerating scientific discovery by leveraging their rich background knowledge and reasoning capabilities. In this paper, we introduce BioDiscoveryAgent, an agent that…

Artificial Intelligence · Computer Science 2025-03-11 Yusuf Roohani , Andrew Lee , Qian Huang , Jian Vora , Zachary Steinhart , Kexin Huang , Alexander Marson , Percy Liang , Jure Leskovec

We show that multi-agent systems guided by vision-language models (VLMs) improve end-to-end autonomous scientific discovery. By treating plots as verifiable checkpoints, a VLM-as-a-judge evaluates figures against dynamically generated…

Computation and Language · Computer Science 2025-11-19 Kahaan Gandhi , Boris Bolliet , Inigo Zubeldia

Recent advances in large language models (LLMs) have stepped forward the development of multilingual speech and machine translation by its reduced representation errors and incorporated external knowledge. However, both translation tasks…

Computation and Language · Computer Science 2024-05-17 Yuchen Hu , Chen Chen , Chao-Han Huck Yang , Ruizhe Li , Dong Zhang , Zhehuai Chen , Eng Siong Chng

Creating end-to-end bioinformatics workflows requires diverse domain expertise, which poses challenges for both junior and senior researchers as it demands a deep understanding of both genomics concepts and computational techniques. While…

Large Language Models (LLMs) achieve competitive results compared to human experts in medical examinations. However, it remains a challenge to apply LLMs to complex clinical decision-making, which requires a deep understanding of medical…

Hallucinations, the generation of apparently convincing yet false statements, remain a major barrier to the safe deployment of LLMs. Building on the strong performance of self-detection methods, we examine the use of structured knowledge…

Computation and Language · Computer Science 2025-12-30 Sahil Kale , Antonio Luca Alfeo

Penetration testing is essential to securing modern web infrastructures, yet traditional manual methods struggle to keep pace with their scale and complexity. Large Language Models (LLMs) offer new opportunities for automating these tasks,…

Cryptography and Security · Computer Science 2026-05-26 William Guanting Li , Alsharif Abuadbba , Kristen Moore , Dan Dongseong Kim

This paper introduces SignAgent, a novel agentic framework that utilises Large Language Models (LLMs) for scalable, linguistically-grounded Sign Language (SL) annotation and dataset curation. Traditional computational methods for SLs often…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Oliver Cory , Ozge Mercanoglu Sincan , Richard Bowden

Large Language Models (LLMs) have revolutionized software engineering (SE), showcasing remarkable proficiency in various coding tasks. Despite recent advancements that have enabled the creation of autonomous software agents utilizing LLMs…

Software Engineering · Computer Science 2025-09-08 Huy Nhat Phan , Tien N. Nguyen , Phong X. Nguyen , Nghi D. Q. Bui

Hypothesis generation in biomedical research has traditionally centered on uncovering hidden relationships within vast scientific literature, often using methods like Literature-Based Discovery (LBD). Despite progress, current approaches…

Computation and Language · Computer Science 2025-11-13 Fuyi Yang , Chenchen Ye , Mingyu Derek Ma , Yijia Xiao , Matthew Yang , Wei Wang

Despite their impressive ability to generate high-quality and fluent text, generative large language models (LLMs) also produce hallucinations: statements that are misaligned with established world knowledge or provided input context.…

Computation and Language · Computer Science 2025-01-15 Abhilasha Ravichander , Shrusti Ghela , David Wadden , Yejin Choi

Large language models (LLMs) have shown impressive capabilities in code generation. However, because most LLMs are trained on public domain corpora, directly applying them to real-world software development often yields low success rates,…

Artificial Intelligence · Computer Science 2026-03-26 Shuai Wang , Dhasarathy Parthasarathy , Robert Feldt , Yinan Yu
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