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We use coarse grained molecular dynamics simulations to investigate diffusion properties of sheared lipid membranes with embedded transmembrane proteins. In membranes without proteins, we find normal in-plane diffusion of lipids in all flow…

Biological Physics · Physics 2013-09-10 Atefeh Khoshnood , Mir Abbas Jalali

We study a reaction-diffusion model posed on two distinct spatial scales that accounts for diffusion, aggregation, fragmentation, and deposition of populations of colloidal particles within a porous material. In this model, the macroscopic…

Analysis of PDEs · Mathematics 2026-04-14 Christos Nikolopoulos , Michael Eden , Adrian Muntean

Molecular communication, as implied by its name, uses molecules as information carriers for communication between objects. It has an advantage over traditional electromagnetic-wave-based communication in that molecule-based systems could be…

Signal Processing · Electrical Eng. & Systems 2023-12-05 Hanlin Xiao , Kamela Dokaj , Ozgur B. Akan

A model of randomly distributed overlapping spheres of different radii is represented to describe a heterogeneous porous medium. Two-particle correlation function of the relative position of pores of different radii in the medium space was…

Soft Condensed Matter · Physics 2016-03-04 V. D. Borman , A. A. Belogorlov , V. A. Byrkin , V. N. Tronin , V. I. Troyan

We present a mathematical study for the development of Multiple Sclerosis in which a spatio-temporal kinetic { theory} model describes, at the mesoscopic level, the dynamics of a high number of interacting agents. We consider both…

Analysis of PDEs · Mathematics 2026-01-07 Romina Travaglini , João Miguel Oliveira

The interactions between diffusing molecules and membrane-bound receptors drive numerous cellular processes. In this work, we develop a spatial model of molecular interactions with membrane receptors by homogenizing the cell membrane and…

Quantitative Methods · Quantitative Biology 2025-01-24 Anil Cengiz , Sean D Lawley

Development in multi-cellular organisms is marked by a high degree of spatial organization of the cells attaining distinct fates in the embryo. We show that receptor-ligand interaction between cells in close physical proximity adaptively…

Tissues and Organs · Quantitative Biology 2021-06-30 Chandrashekar Kuyyamudi , Shakti N. Menon , Sitabhra Sinha

We study a stochastic epidemic model consisting of elements (organisms in a community or cells in tissue) with fixed positions, in which damage or disease is transmitted by diffusing agents ("signals") emitted by infected individuals. The…

Populations and Evolution · Quantitative Biology 2015-06-05 Fernando P. Faria , Ronald Dickman

The reversible reactions like A+B <-> C in the many-component diffusive system affect the diffusive properties of the constituents. The effective conjugation of irreversible processes of different dimensionality takes place due to the…

Other Condensed Matter · Physics 2007-05-23 Serge Shpyrko , Vladimir M. Sysoev

In this work, receiver diversity in advection-dominated diffusion-advection channels is investigated. Strong directed flow fundamentally alters the communication-theoretic properties of molecular communication systems (MC). Specifically,…

Signal Processing · Electrical Eng. & Systems 2026-02-02 Fatih Merdan , Ozgur B. Akan

Living systems relay information across membrane interfaces to coordinate compartment functions. We identify a physical mechanism for selective information transmission that arises from the sigmoidal response of surface-bound particle…

Statistical Mechanics · Physics 2025-12-29 Jenna Elliott , Hiral Shah , Roman Belousov , Gautam Dey , Anna Erzberger

The fundamental processes of biological development are governed by multiple signaling molecules that create non-uniform concentration profiles known as morphogen gradients. It is widely believed that the establishment of morphogen…

Biological Physics · Physics 2015-06-18 Hamid Teimouri , Anatoly B. Kolomeisky

The problem of diffusion in a porous medium with a spatially varying porosity is considered. The particular microstructure analyzed comprises a collection of impenetrable spheres, though the methods developed are general. Two different…

Fluid Dynamics · Physics 2017-10-12 Maria Bruna , S. Jonathan Chapman

In this paper an analytical model is introduced to describe the impulse response of the diffusive channel between a pointwise transmitter and a given fully-absorbing (FA) receiver in a molecular communication (MC) system. The presence of…

Information Theory · Computer Science 2021-11-25 Marco Ferrari , Fardad Vakilipoor , Eric Regonesi , Mariangela Rapisarda , Maurizio Magarini

Cell spreading is investigated at various scales in order to understand motility of living cells which is essential for a range of physiological activities in higher organisms as well as in microbes. At a microscopic scale, it has been seen…

Cell Behavior · Quantitative Biology 2009-11-13 A. Bhattacharyay

By considering potential health problems that a fully covering receiver may cause in vessel-like environments, the implementation of a partially covering receiver is needed. To this end, distribution of hitting location of messenger…

Emerging Technologies · Computer Science 2018-02-06 Meriç Turan , Mehmet Sukru Kuran , H. Birkan Yilmaz , Ilker Demirkol , Tuna Tugcu

We investigate the influence of multiscale aggregation and deposition on the colloidal dynamics in a saturated porous medium. At the pore scale, the aggregation of colloids is modeled by the Smoluchowski equation. Essentially, the colloidal…

Analysis of PDEs · Mathematics 2014-04-17 Oleh Krehel , Adrian Muntean , Peter Knabner

This survey paper focuses on modulation aspects of molecular communication, an emerging field focused on building biologically-inspired systems that embed data within chemical signals. The primary challenges in designing these systems are…

Emerging Technologies · Computer Science 2020-12-29 Mehmet Sukru Kuran , H. Birkan Yilmaz , Ilker Demirkol , Nariman Farsad , Andrea Goldsmith

Using the notion of effective distance proposed by Brockmann and Helbing, complex spatiotemporal processes of epidemic spreading can be reduced to circular wave propagation patterns with well-defined wavefronts. This hidden homogeneity of…

Physics and Society · Physics 2018-02-13 Yifan Chen , Yu Zhou , Ross Murch , Tadashi Nakano

Three-dimensional molecular generators based on diffusion models can now reach near-crystallographic accuracy, yet they remain fragmented across tasks. SMILES-only inputs, two-stage pretrain-finetune pipelines, and one-task-one-model…

Biomolecules · Quantitative Biology 2025-07-11 Dong Xu , Zhangfan Yang , Sisi Yuan , Jenna Xinyi Yao , Jiangqiang Li , Junkai Ji