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Mutual information (MI) is a fundamental measure of statistical dependence between two variables, yet accurate estimation from finite data remains notoriously difficult. No estimator is universally reliable, and common approaches fail in…

Data Analysis, Statistics and Probability · Physics 2025-10-02 Eslam Abdelaleem , K. Michael Martini , Ilya Nemenman

Missing observations are common in cluster randomised trials. Approaches taken to handling such missing data include: complete case analysis, single-level multiple imputation that ignores the clustering, multiple imputation with a fixed…

Methodology · Statistics 2014-07-18 Karla Diaz-Ordaz , Michael G. Kenward , Manuel Gomes , Richard Grieve

Estimating causal effects for survival outcomes in the high-dimensional setting is an extremely important topic for many biomedical applications as well as areas of social sciences. We propose a new orthogonal score method for treatment…

Methodology · Statistics 2024-12-04 Jue Hou , Jelena Bradic , Ronghui Xu

Deep learning (DL) has been used in the automatic diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) with brain imaging data. However, previous methods have not fully exploited the relation between brain image and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Luoyao Kang , Haifan Gong , Xiang Wan , Haofeng Li

Despite their impressive capabilities, large language models (LLMs) have been observed to generate responses that include inaccurate or fabricated information, a phenomenon commonly known as ``hallucination''. In this work, we propose a…

Computation and Language · Computer Science 2024-03-12 Yue Zhang , Leyang Cui , Wei Bi , Shuming Shi

Hallucinations in large vision-language models (LVLMs) pose significant challenges for real-world applications, as LVLMs may generate responses that appear plausible yet remain inconsistent with the associated visual content. This issue…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Xin Dong , Shichao Dong , Jin Wang , Jing Huang , Li Zhou , Zenghui Sun , Lihua Jing , Jingsong Lan , Xiaoyong Zhu , Bo Zheng

Modern high-throughput biomedical devices routinely produce data on a large scale, and the analysis of high-dimensional datasets has become commonplace in biomedical studies. However, given thousands or tens of thousands of measured…

Methodology · Statistics 2022-02-28 Vladimir Vutov , Thorsten Dickhaus

Vision-language foundation models (VLMs) show promise for diverse imaging tasks but often underperform on medical benchmarks. Prior efforts to improve performance include model finetuning, which requires large domain-specific datasets and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Arnav Singhvi , Vasiliki Bikia , Asad Aali , Akshay Chaudhari , Roxana Daneshjou

Machine Learning (ML) applications on healthcare can have a great impact on people's lives helping deliver better and timely treatment to those in need. At the same time, medical data is usually big and sparse requiring important…

Machine Learning · Computer Science 2018-12-27 Dianbo Liu , Nestor Sepulveda , Ming Zheng

The early detection of Alzheimer's Disease is imperative to ensure early treatment and improve patient outcomes. There has consequently been extenstive research into detecting AD and its intermediate phase, mild cognitive impairment (MCI).…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Jamie Vo , Naeha Sharif , Ghulam Mubashar Hassan

Multi-scenario ad ranking aims at leveraging the data from multiple domains or channels for training a unified ranking model to improve the performance at each individual scenario. Although the research on this task has made important…

Information Retrieval · Computer Science 2023-02-07 Shanlei Mu , Penghui Wei , Wayne Xin Zhao , Shaoguo Liu , Liang Wang , Bo Zheng

High-dimensional and incomplete (HDI) data holds tremendous interactive information in various industrial applications. A latent factor (LF) model is remarkably effective in extracting valuable information from HDI data with stochastic…

Machine Learning · Computer Science 2022-08-05 Jinli Li , Ye Yuan

In previous works, we proposed to estimate cosmological parameters with the artificial neural network (ANN) and the mixture density network (MDN). In this work, we propose an improved method called the mixture neural network (MNN) to…

Cosmology and Nongalactic Astrophysics · Physics 2023-08-23 Guo-Jian Wang , Cheng Cheng , Yin-Zhe Ma , Jun-Qing Xia , Amare Abebe , Aroonkumar Beesham

Stacking excessive layers in DNN results in highly underdetermined system when training samples are limited, which is very common in medical applications. In this regard, we present a framework capable of deriving an efficient…

Machine Learning · Computer Science 2025-03-04 Seunghun Baek , Injun Choi , Mustafa Dere , Minjeong Kim , Guorong Wu , Won Hwa Kim

Alzheimer's Disease (AD) is the most common neurodegenerative disorder with one of the most complex pathogeneses, making effective and clinically actionable decision support difficult. The objective of this study was to develop a novel…

Machine Learning · Computer Science 2022-09-27 Michal Golovanevsky , Carsten Eickhoff , Ritambhara Singh

Observational epidemiological studies commonly seek to estimate the causal effect of an exposure on an outcome. Adjustment for potential confounding bias in modern studies is challenging due to the presence of high-dimensional confounding,…

Methodology · Statistics 2025-08-29 Susan Ellul , Stijn Vansteelandt , John B. Carlin , Margarita Moreno-Betancur

With Motor-Imagery (MI) Brain--Machine Interfaces (BMIs) we may control machines by merely thinking of performing a motor action. Practical use cases require a wearable solution where the classification of the brain signals is done locally…

Signal Processing · Electrical Eng. & Systems 2021-02-23 Xiaying Wang , Tibor Schneider , Michael Hersche , Lukas Cavigelli , Luca Benini

Evaluating and tracking patients' functional status through the post-acute care continuum requires a common instrument. However, different post-acute service providers such as nursing homes, inpatient rehabilitation facilities and home…

Methodology · Statistics 2020-01-22 Chenyang Gu , Roee Gutman

The ability to predict the progression of biomarkers, notably in NDD, is limited by the size of the longitudinal data sets, in terms of number of patients, number of visits per patients and total follow-up time. To this end, we introduce a…

Methodology · Statistics 2019-04-08 Igor Koval , Stéphanie Allassonnière , Stanley Durrleman

Some of the issues that make sampling parameter spaces of various beyond the Standard Model (BSM) scenarios computationally expensive are the high dimensionality of the input parameter space, complex likelihoods, and stringent experimental…

High Energy Physics - Phenomenology · Physics 2026-02-16 Atrideb Chatterjee , Arghya Choudhury , Sourav Mitra , Arpita Mondal , Subhadeep Mondal