Related papers: High-dimensional multiple imputation (HDMI) for pa…

We introduce conditional flow matching for imputation (CFMI), a new general-purpose method to impute missing data. The method combines continuous normalising flows, flow-matching, and shared conditional modelling to deal with…

Multi-modal large language models (MLLMs) have been shown to efficiently integrate natural language with visual information to handle multi-modal tasks. However, MLLMs still face a fundamental limitation of hallucinations, where they tend…

Hallucinations in large language models (LLMs) pose significant safety concerns that impede their broader deployment. Recent research in hallucination detection has demonstrated that LLMs' internal representations contain truthfulness…

This work proposes an algorithm for fMRI data analysis for the classification of ADHD disorders. There have been several breakthroughs in the analysis of fMRI via 3D convolutional neural networks (CNNs). With these new techniques it is…

Modern biomedical survival studies with high-dimensional genomic and clinical predictors are challenged by missing covariates. Existing methods conduct inference through penalization and debiasing when the number of covariates diverges with…

Proximal causal inference (PCI) is a recently proposed framework to identify and estimate the causal effect of an exposure on an outcome in the presence of hidden confounders, using observed proxies. Specifically, PCI relies on two types of…

This paper applies a hidden Markov model to the problem of Attention Deficit Hyperactivity Disorder (ADHD) diagnosis from resting-state functional Magnetic Resonance Image (fMRI) scans of subjects. The proposed model considers the temporal…

A mediation analysis approach is proposed for multiple exposures, multiple mediators, and a continuous scalar outcome under the linear structural equation modeling framework. It assumes that there exist orthogonal components that…

The global prevalence of dementia is projected to double by 2050, highlighting the urgent need for scalable diagnostic tools. This study utilizes digital cognitive tasks with eye-tracking data correlated with memory processes to distinguish…

Medical artificial intelligence (AI) systems, particularly multimodal vision-language models (VLM), often exhibit intersectional biases where models are systematically less confident in diagnosing marginalised patient subgroups. Such bias…

We provide guidance on multiple imputation of missing at random treatments in observational studies. Specifically, analysts should account for both covariates and outcomes, i.e., not just use propensity scores, when imputing the missing…

Diabetic retinopathy (DR) is a leading cause of blindness worldwide, and AI systems can expand access to fundus photography screening. Current FDA-cleared systems primarily provide binary referral outputs, where this minimal output may…

Hyperdimensional Computing (HDC) is a brain-inspired computing paradigm that represents and manipulates information using high-dimensional vectors, called hypervectors (HV). Traditional HDC methods, while robust to noise and inherently…

Three-level data structures arising from repeated measures on individuals clustered within larger units are common in health research studies. Missing data are prominent in such studies and are often handled via multiple imputation (MI).…

The accurate diagnosis of Alzheimer's disease (AD) and prognosis of mild cognitive impairment (MCI) conversion are crucial for early intervention. However, existing multimodal methods face several challenges, from the heterogeneity of input…

Although Large Audio-Language Models (LALMs) deliver state-of-the-art (SOTA) performance, they frequently suffer from hallucinations, e.g. generating text not grounded in the audio input. We analyze these grounding failures and identify a…

Diabetic Peripheral Neuropathy (DPN) affects nearly half of diabetes patients, requiring early detection. Corneal Confocal Microscopy (CCM) enables non-invasive diagnosis, but automated methods suffer from inefficient feature extraction,…

Marginal structural models (MSMs) are commonly used to estimate causal intervention effects in longitudinal non-randomised studies. A common issue when analysing data from observational studies is the presence of incomplete confounder data,…

Despite recent successes, LVLMs or Large Vision Language Models are prone to hallucinating details like objects and their properties or relations, limiting their real-world deployment. To address this and improve their robustness, we…

The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer's disease (AD) is clinically relevant, and may above all have a significant impact on accelerate the development of new treatments. In this…