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Related papers: High-dimensional multiple imputation (HDMI) for pa…

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Including a large number of predictors in the imputation model underlying a multiple imputation (MI) procedure is one of the most challenging tasks imputers face. A variety of high-dimensional MI techniques can help, but there has been…

Methodology · Statistics 2023-08-15 Edoardo Costantini , Kyle M. Lang , Tim Reeskens , Klaas Sijtsma

Propensity score matching (PSM) has been widely used to mitigate confounding in observational studies, although complications arise when the covariates used to estimate the PS are only partially observed. Multiple imputation (MI) is a…

Applications · Statistics 2021-07-22 Albee Y. Ling , Maria E. Montez-Rath , Maya B. Mathur , Kris Kapphahn , Manisha Desai

Missing data present challenges in data analysis. Naive analyses such as complete-case and available-case analysis may introduce bias and loss of efficiency, and produce unreliable results. Multiple imputation (MI) is one of the most widely…

Methodology · Statistics 2019-05-15 Domonique W. Hodge , Sandra E. Safo , Qi Long

Multiple imputation (MI) has been widely applied to missing value problems in biomedical, social and econometric research, in order to avoid improper inference in the downstream data analysis. In the presence of high-dimensional data,…

Methodology · Statistics 2023-05-04 Zhiqi Bu , Zongyu Dai , Yiliang Zhang , Qi Long

Mild Cognitive Impairment (MCI) serves as a prodromal stage of Alzheimer's Disease (AD), where early identification and intervention can effectively slow the progression to dementia. However, diagnosing AD remains a significant challenge in…

Artificial Intelligence · Computer Science 2025-11-07 Yutao Jin , Haowen Xiao , Junyong Zhai , Yuxiao Li , Jielei Chu , Fengmao Lv , Yuxiao Li

Multiple imputation (MI) is a popular method for handling missing data. Auxiliary variables can be added to the imputation model(s) to improve MI estimates. However, the choice of which auxiliary variables to include in the imputation model…

Missingness is a common issue for neuroimaging data, and neglecting it in downstream statistical analysis can introduce bias and lead to misguided inferential conclusions. It is therefore crucial to conduct appropriate statistical methods…

Methodology · Statistics 2025-03-25 Tong Lu , Chixiang Chen , Hsin-Hsiung Huang , Peter Kochunov , Elliot Hong , Shuo Chen

Large Vision-Language Models (VLMs) have achieved remarkable success across diverse multimodal tasks but remain vulnerable to hallucinations rooted in inherent language bias. Despite recent progress, existing hallucination mitigation…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Yilin Yang , Zhenghui Guo , Yuke Wang , Omprakash Gnawali , Sheng Di , Chengming Zhang

In this paper, we introduce fastHDMI, a Python package designed for efficient variable screening in high-dimensional datasets, particularly neuroimaging data. This work pioneers the application of three mutual information estimation methods…

Machine Learning · Statistics 2024-10-15 Kai Yang , Masoud Asgharian , Nikhil Bhagwat , Jean-Baptiste Poline , Celia M. T. Greenwood

High-dimensional neuroimaging and spatiotemporal blocks often contain structured missingness from acquisition artifacts, preprocessing failures, and sensor dropout. Multiple imputation propagates uncertainty, but fully conditional…

Methodology · Statistics 2026-05-07 Hsin-Hsiung Huang , Stef van Buuren

The use of flexible machine-learning (ML) models to generate imputations of missing data within the framework of Multiple Imputation (MI) has recently gained traction, particularly in observational settings. For randomised controlled trials…

Methodology · Statistics 2025-10-07 Mia S. Tackney , Jonathan W. Bartlett , Elizabeth Williamson , Kim May Lee

Deep learning has been successful in predicting neurodegenerative disorders, such as Alzheimer's disease, from magnetic resonance imaging (MRI). Combining multiple imaging modalities, such as T1-weighted (T1) and diffusion-weighted imaging…

Artificial Intelligence · Computer Science 2026-01-30 Abhijith Shaji , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Greg Ver Steeg , Paul M. Thompson , Jose-Luis Ambite

Multiple imputation (MI) is a method for repairing and analyzing data with missing values. MI replaces missing values with a sample of random values drawn from an imputation model. The most popular form of MI, which we call posterior draw…

Methodology · Statistics 2019-11-18 Paul T. von Hippel , Jonathan Bartlett

Causal probing methods aim to test and control how internal representations influence the behavior of generative models. In causal probing, an intervention modifies hidden states so that a property takes on a different value. Most existing…

Artificial Intelligence · Computer Science 2026-05-11 Sadegh Khorasani , Saber Salehkaleybar , Negar Kiyavash , Matthias Grossglauser

Missing covariate data commonly occur in epidemiological and clinical research, and are often dealt with using multiple imputation (MI). Imputation of partially observed covariates is complicated if the substantive model is non-linear (e.g.…

Methodology · Statistics 2014-02-17 Jonathan W. Bartlett , Shaun R. Seaman , Ian R. White , James R. Carpenter

Medical imaging and multi-modal clinical settings often face the challange of missing modality in their diagnostic pipelines. Existing imputation methods either lack representational capacity or are computationally expensive. We propose…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Afifa Khaled , Ebrahim Hamid Sumiea

Mutual information (MI) is a general measure of statistical dependence with widespread application across the sciences. However, estimating MI between multi-dimensional variables is challenging because the number of samples necessary to…

Quantitative Methods · Quantitative Biology 2025-03-06 Gokul Gowri , Xiao-Kang Lun , Allon M. Klein , Peng Yin

Multiple imputation (MI) is an established technique to handle missing data in observational studies. Joint modeling (JM) and fully conditional specification (FCS) are commonly used methods for imputing multilevel clustered data. However,…

Methodology · Statistics 2022-09-28 Mei Dong , Aya Mitani

In randomized controlled trials, adjusting for baseline covariates is often applied to improve the precision of treatment effect estimation. However, missingness in covariates is common. Recently, Zhao & Ding (2022) studied two simple…

Methodology · Statistics 2024-08-28 Yilin Song , James P. Hughes , Ting Ye

A high-dimensional and incomplete (HDI) matrix frequently appears in various big-data-related applications, which demonstrates the inherently non-negative interactions among numerous nodes. A non-negative latent factor (NLF) model performs…

Machine Learning · Computer Science 2022-10-25 Ye Yuan , Xin Luo
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