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While contrast-enhanced CT (CECT) is standard for assessing abdominal aortic aneurysms (AAA), the required iodinated contrast agents pose significant risks, including nephrotoxicity, patient allergies, and environmental harm. To reduce…
Ultrasound offers promising applications in biology and chemistry, but quantifying local ultrasound conditions remains challenging due to the lack of non-invasive measurement tools. We introduce antibubbles as novel optical reporters of…
In this methods paper, we explore the capabilities of high-speed ultrasound imaging (USI) to study fast varying and complex multi-phase structures in liquids and soft materials. Specifically, we assess the advantages and the limitations of…
While the acoustic properties of solid foams have been abundantly characterized, sound propagation in liquid foams remains poorly understood. Recent studies have investigated the transmission of ultrasound through three-dimensional…
Waves scattered by a weakly inhomogeneous random medium contain a predominant single scattering contribution as well as a multiple scattering contribution which is usually neglected, especially for imaging purposes. A method based on random…
An alternative approach to ultrasound computed tomography (USCT) for medical imaging is proposed, with the intent to (i) shorten acquisition time for devices with a large number of emitters, (ii) eliminate the calibration step, and (iii)…
Imaging the human brain vasculature with high spatial and temporal resolution remains challenging in the clinic today. Transcranial ultrasound is scarcely used for cerebrovascular imaging, due to low sensitivity and strong phase aberrations…
Gaseous microemboli (GME) introduced during cardiac surgery are considered as a potential source of morbidity, which has driven the development of the first bubble counters. Two new generation bubble counters claim correct sizing and…
Correct measurement of the shell properties of coated microbubbles (MBs) is essential to understanding and optimizing their response to ultrasound (US) exposure parameters in diagnostic and therapeutic ultrasound. MBs are surrounded by…
Super-resolution ultrasound imaging through microbubble (MB) localisation and tracking, also known as ultrasound localisation microscopy, allows non-invasive sub-diffraction resolution imaging of microvasculature in animals and humans. The…
Pump-probe microscopy is an emerging nonlinear imaging technique based on high repetition rate lasers and fast intensity modulation. Here we present new methods for pump-probe microscopy that keep the beam intensity constant and instead…
Magnetic resonance (MR) images from multiple sources often show differences in image contrast related to acquisition settings or the used scanner type. For long-term studies, longitudinal comparability is essential but can be impaired by…
Subharmonic response from contrast microbubbles as a function of ambient overpressure is numerically investigated for subharmonic aided noninvasive estimation of local organ level blood pressure. Three different interfacial rheological…
In the recent years, we witness a great interest in imaging, in a wide sense, using contrast agents. One of the reasons is that many imaging modalities, as the ones related to medical sciences, suffer from several shortcomings. The most…
The development of medium-energy inelastic X-ray scattering (IXS) optics with meV and sub-meV resolution has attracted considerable efforts in recent years. Meanwhile, there are also concerns or debates about the fundamental and feasibility…
Multi-contrast MRI protocols increase the level of morphological information available for diagnosis. Yet, the number and quality of contrasts is limited in practice by various factors including scan time and patient motion. Synthesis of…
A growing class of ultrasound-mediated diagnostic and therapeutic technologies, including sonoporation and blood-brain barrier modulation, relies on microbubble contrast agents, where precise control of microbubble dynamics governs…
Different imaging modalities are used to extract the diverse information carried in an optical field. Two prominent modalities include bright field and phase contrast microscopy that can visualize the amplitude and phase features of a…
Recently, super-resolution ultrasound imaging with ultrasound localization microscopy (ULM) has received much attention. However, ULM relies on low concentrations of microbubbles in the blood vessels, ultimately resulting in long…
Ultrasound Localization Microscopy can resolve the microvascular bed down to a few micrometers. To achieve such performance microbubble contrast agents must perfuse the entire microvascular network. Microbubbles are then located…