Related papers: Polydisperse versus monodisperse microbubbles: A s…
In the paper, we succeeded to freeze-dry monodisperse microbubbles without degrading their size and acoustic properties. We used microfluidic technology to generate highly monodisperse (coefficient of variation, CV<5%) microbubbles and…
The importance of the excitation bandwidth is well known in diagnostic ultrasound imaging. However, the effect of excitation bandwidth in therapeutic applications of microbubbles has been mostly overlooked. A majority of contrast agent…
Monodisperse lipid-coated microbubbles are a promising route to unlock the full potential of ultrasound contrast agents for medical diagnosis and therapy. Here, we present a stand-alone lab-on-a-chip instrument that allows microbubbles to…
Contrast-Enhanced Ultra-Sound (CEUS) has become a viable method for non-invasive, dynamic visualization in medical diagnostics, yet Ultrasound Localization Microscopy (ULM) has enabled a revolutionary breakthrough by offering ten times…
We present measurements of the diffusion coefficient of ultrasound in strongly scattering three-dimensional (3D) disordered media using the dynamic coherent backscattering (CBS) effect. Our experiments measure the CBS of ultrasonic waves…
Subharmonics emitted from microbubble-based ultrasound contrast agents (UCA) are considered as a noninvasive indicator for diagnostic applications in medical fields. Contrast ultrasound imaging using the modality of subharmonics could be…
Acoustic microstreaming has several industrial, therapeutic, and biomedical applications - Acoustic cleaning, micromixing, microfluid transport, hemolysis, sonoporation. The acoustic microstreaming due to the oscillation of ultrasound…
Purpose: This work aims to raise a novel design for navigator-free multiband (MB) multishot uniform-density spiral (UDS) acquisition and reconstruction, and to demonstrate its utility for high-efficiency, high-resolution diffusion imaging.…
Acoustic characterization of ultrasound contrast agents (UCAs, coated microbubbles) relies on the attenuation theory that assumes the UCAs oscillate linearly at sufficiently low excitation pressures. Effective shell parameters of the UCAs…
We analyze mathematically the acoustic imaging modality using bubbles as contrast agents. These bubbles are modeled by mass densities and bulk moduli enjoying contrasting scales. These contrasting scales allow them to resonate at certain…
Super-resolution ultrasound (SRUS) imaging through localising and tracking sparse microbubbles has been shown to reveal microvascular structure and flow beyond the wave diffraction limit. Most SRUS studies use standard delay and sum (DAS)…
Contrast Enhanced Spectral Mammography (CESM) is a dual-energy mammographic imaging technique that first needs intravenously administration of an iodinated contrast medium; then, it collects both a low-energy image, comparable to standard…
An antibubble is a gas bubble with a liquid droplet inside. Antibubbles have a potential role in ultrasonic imaging, ultrasound-guided drug delivery, and hydrocarbon leakage detection. The liquid core droplets inside antibubbles can be…
Dynamic contrast-enhanced (DCE) MRI is essential for breast cancer diagnosis and treatment. However, its reliance on contrast agents introduces safety concerns, contraindications, increased cost, and workflow complexity. To this end, we…
Ultrasound imaging of the cortex of long bones may enable the measurement of the cortical thickness and the ultrasound wave speed in cortical bone tissue. However, with bone loss, the cortical porosity and the size of the pores increase,…
A photoacoustic contrast mechanism is presented based on the photoacoustic fluctuations induced by microbubbles flowing inside a micro vessel filled with a continuous absorber. It is demonstrated that the standard deviation of a homogeneous…
In the present paper we consider the problem of Laplace deconvolution with noisy discrete observations. The study is motivated by Dynamic Contrast Enhanced imaging using a bolus of contrast agent, a procedure which allows considerable…
Ultrasound imaging, despite its widespread use in medicine, often suffers from various sources of noise and artifacts that impact the signal-to-noise ratio and overall image quality. Enhancing ultrasound images requires a delicate balance…
We study nonlinear dynamics of two coupled contrast agents that are micro-meter size gas bubbles encapsulated into a viscoelastic shell. Such bubbles are used for enhancing ultrasound visualization of blood flow and have other promising…
Ultrasound is known to enhance surface bubble growth and removal in catalytic and microfluidic applications, yet the contributions of rectified diffusion and microstreaming phenomena towards mass transfer remain unclear. We quantify the…