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We show the first non-trivial positive algorithmic results (i.e. programs whose output is larger than their size), in a model of self-assembly that has so far resisted many attempts of formal analysis or programming: the planar…

Computational Geometry · Computer Science 2014-07-11 Pierre-Étienne Meunier

In this paper we consider the problem of the strict self-assembly of infinite fractals within tile self-assembly. In particular, we provide tile assembly algorithms for the assembly of the discrete Sierpinski triangle and the discrete…

Computational Geometry · Computer Science 2015-05-26 Cameron T. Chalk , Dominic A. Fernandez , Alejandro Huerta , Mario A. Maldonado , Robert T. Schweller , Leslie Sweet

DNA origami consists of a long scaffold strand and short staple strands that self-assemble into a target 2D or 3D shape. It is a widely used construct in nucleic acid nanotechnology, offering a cost-effective way to design and create…

Soft Condensed Matter · Physics 2024-09-23 Sarah Haggenmueller , Michael Matthies , Matthew Sample , Petr Šulc

DNA nanotechnology allows for the realization of complex nanoarchitectures in which the spatial arrangements of different constituents and most functions can be enabled by DNA. When optically active components are integrated in such…

Biological Physics · Physics 2021-05-10 Pengfei Zhan , Steffen Both , Thomas Weiss , Na Liu

DNA nanoparticles with three-fold coordination have been observed to self-assemble in experiment into a network equivalent to the hexagonal (6.6.6) tiling, and a network equivalent to the 4.8.8 Archimedean tiling. Both networks are built…

Statistical Mechanics · Physics 2018-05-28 Zdenek Preisler , Barbara Sacca , Stephen Whitelam

In this paper, we work in a 2D version of the probabilistic variant of Winfree's abstract Tile Assembly Model defined by Chandran, Gopalkrishnan and Reif (SICOMP 2012) in which attaching tiles are sampled uniformly with replacement. First,…

Data Structures and Algorithms · Computer Science 2024-08-13 David Furcy , Scott M. Summers

DNA origami is a widely used method to construct nanostructures by self-assembling designed DNA strands. These structures are often used as "pegboards" for templated assembly of proteins, gold nanoparticles, aptamers, and other molecules,…

Soft Condensed Matter · Physics 2024-11-05 Matthew Sample , Hao Liu , Thong Diep , Michael Matthies , Petr Šulc

We present algorithmic results for the parallel assembly of many micro-scale objects in two and three dimensions from tiny particles, which has been proposed in the context of programmable matter and self-assembly for building high-yield…

Data Structures and Algorithms · Computer Science 2017-09-20 Aaron T. Becker , Sándor P. Fekete , Phillip Keldenich , Dominik Krupke , Christian Rieck , Christian Scheffer , Arne Schmidt

An oritatami system (OS) is a theoretical model of self-assembly via co-transcriptional folding. It consists of a growing chain of beads which can form bonds with each other as they are transcribed. During the transcription process, the…

Data Structures and Algorithms · Computer Science 2018-07-16 Erik D. Demaine , Jacob Hendricks , Meagan Olsen , Matthew J. Patitz , Trent A. Rogers , Nicolas Schabanel , Shinnosuke Seki , Hadley Thomas

Patterned self-assembly is a process whereby coloured tiles self-assemble to build a rectangular coloured pattern. We propose self-assembly (SA) hypergraph automata as an automata-theoretic model for patterned self-assembly. We investigate…

Discrete Mathematics · Computer Science 2013-02-13 Lila Kari , Steffen Kopecki , Amirhossein Simjour

Blending representation learning approaches with simultaneous localization and mapping (SLAM) systems is an open question, because of their highly modular and complex nature. Functionally, SLAM is an operation that transforms raw sensor…

Robotics · Computer Science 2020-11-20 Krishna Murthy Jatavallabhula , Soroush Saryazdi , Ganesh Iyer , Liam Paull

The ever-increasing power of supercomputers coupled with highly scalable simulation codes have made molecular dynamics an indispensable tool in applications ranging from predictive modeling of materials to computational design and discovery…

Computational Engineering, Finance, and Science · Computer Science 2020-02-25 Henry Chan , Badri Narayanan , Mathew Cherukara , Troy D. Loeffler , Michael G. Sternberg , Anthony Avarca , Subramanian K. R. S. Sankaranarayanan

Recent advancements in microbiology have motivated the study of the production of nanostructures with applications such as biomedical computing and molecular robotics. One way to construct these structures is to construct branched DNA…

We describe a novel geometric methodology for analyzing free-energy and kinetics of assembly driven by short-range pair-potentials in an implicit solvent, and provides illustrations of its unique capabilities. An atlas is a labeled…

Computational Geometry · Computer Science 2020-10-19 Rahul Prabhu , Meera Sitharam , Aysegul Ozkan , Ruijin Wu

We prove the computational weakness of a model of tile assembly that has so far resisted many attempts of formal analysis or positive constructions. Specifically, we prove that, in Winfree's abstract Tile Assembly Model, when restricted to…

Computational Complexity · Computer Science 2015-07-31 Pierre-Étienne Meunier , Damien Regnault

The accurate assembly of the system matrix is an important step in any code that solves partial differential equations on a mesh. We either explicitly set up a matrix, or we work in a matrix-free environment where we have to be able to…

Mathematical Software · Computer Science 2020-06-19 Charles D. Murray , Tobias Weinzierl

DNA based nanostructures built on a long single stranded DNA scaffold, known as DNA origamis, offer the possibility to organize various molecules at the nanometer scale in one pot experiments. The folding of the scaffold is guaranteed by…

Mesoscale and Nanoscale Physics · Physics 2012-10-03 Jean-Michel Arbona , Jean-Pierre Aimé , Juan Elezgaray

General matrix multiplication (GEMM) is the computational backbone of modern AI workloads, and its efficiency is critically dependent on effective tiling strategies. Conventional approaches employ symmetric tile buffering, where the…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-21 Chengyue Wang , Wesley Pang , Xinrui Wu , Gregory Jun , Luis Romero , Endri Taka , Diana Marculescu , Tony Nowatzki , Pranathi Vasireddy , Joseph Melber , Deming Chen , Jason Cong

We show the first asymptotically efficient constructions in the so-called "noncooperative planar tile assembly" model. Algorithmic self-assembly is the study of the local, distributed, asynchronous algorithms ran by molecules to…

Computational Complexity · Computer Science 2021-07-19 Pierre-Etienne Meunier , Damien Regnault

We present a modular DNA origami design approach to address the challenges of assembling geometrically complex nanoscale structures, including those with nonuniform Gaussian curvature. This approach features a core structure that completely…

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