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In this paper we demonstrate the power of a model of tile self-assembly based on active glues which can dynamically change state. We formulate the Signal-passing Tile Assembly Model (STAM), based on the model of Padilla, Liu, and Seeman to…

Sophisticated statistical mechanics approaches and human intuition have demonstrated the possibility to self-assemble complex lattices or finite size constructs, but have mostly only been successful in silico. The proposed strategies quite…

We prove a Pumping Lemma for the noncooperative abstract Tile Assembly Model, a model central to the theory of algorithmic self-assembly since the beginning of the field. This theory suggests, and our result proves, that small differences…

Computational Complexity · Computer Science 2020-02-11 Pierre-Étienne Meunier , Damien Regnault , Damien Woods

We present a simple route to circumvent kinetic traps which affect many types of DNA nanostructures in their self-assembly process. Using this method, a new 2D DNA lattice made up of short, single-stranded tile (SST) motifs was created.…

Materials Science · Physics 2016-01-20 Junghoon Kim , Tai Hwan Ha , Sung Ha Park

Self-assembly refers to the process by which small, simple components mix and combine to form complex structures using only local interactions. Designed as a hybrid between tile assembly models and cellular automata, the Tile Automata (TA)…

Emerging Technologies · Computer Science 2019-06-06 John Calvin Alumbaugh , Joshua J. Daymude , Erik D. Demaine , Matthew J. Patitz , Andrea W. Richa

Tile Automata is a recently defined model of self-assembly that borrows many concepts from cellular automata to create active self-assembling systems where changes may be occurring within an assembly without requiring attachment. This model…

Formal Languages and Automata Theory · Computer Science 2022-11-28 Robert M. Alaniz , David Caballero , Sonya C. Cirlos , Timothy Gomez , Elise Grizzell , Andrew Rodriguez , Robert Schweller , Armando Tenorio , Tim Wylie

Pattern self-assembly tile set synthesis (PATS) is a combinatorial optimization problem which aim at minimizing a rectilinear tile assembly system (RTAS) that uniquely self-assembles a given rectangular pattern, and is known to be NP-hard.…

Computational Complexity · Computer Science 2013-01-17 Shinnosuke Seki

In this paper, we prove that in the abstract Tile Assembly Model (aTAM), an accretion-based model which only allows for a single tile to attach to a growing assembly at each step, there are no tile assembly systems capable of…

Emerging Technologies · Computer Science 2018-07-18 Jacob Hendricks , Joseph Opseth , Matthew Patitz , Scott Summers

Tile displacement is a newly-recognized mechanism in DNA nanotechnology that exploits principles analogous to toehold-mediated strand displacement but within the context of self-assembled DNA origami tile arrays. Here, we formulate an…

Emerging Technologies · Computer Science 2023-01-06 Erik Winfree , Lulu Qian

Tile-based self-assembly systems are capable of universal computation and algorithmically-directed growth. Systems capable of such behavior typically make use of "glue cooperation" in which the glues on at least $2$ sides of a tile must…

Emerging Technologies · Computer Science 2019-03-15 Daniel Hader , Matthew J. Patitz

The observation by Ke et al. [Science 338, 1177 (2012)] that large numbers of short, pre-designed DNA strands can assemble into three-dimensional target structures came as a great surprise, as no colloidal self-assembling system has ever…

Soft Condensed Matter · Physics 2014-06-12 Aleks Reinhardt , Daan Frenkel

A physically-motivated genetic algorithm (GA) and full enumeration for a tile-based model of self-assembly (JaTAM) is implemented using a graphics processing unit (GPU). We observe performance gains with respect to state-of-the-art…

Neural and Evolutionary Computing · Computer Science 2022-06-01 Christian Schroeder de Witt

The optimal design of DNA origami systems that assemble rapidly and robustly is hampered by the lack of a model for self-assembly that is sufficiently detailed yet computationally tractable. Here, we propose a model for DNA origami that…

Soft Condensed Matter · Physics 2019-01-07 Alexander Cumberworth , Aleks Reinhardt , Daan Frenkel

At the cutting edge of materials science, matter is designed to self-organize into structures that perform a wide range of functions. The past two decades have witnessed major innovations in the versatility of building blocks, ranging from…

Soft Condensed Matter · Physics 2022-09-26 Angus McMullen , Maitane Muñoz Basagoiti , Zorana Zeravcic , Jasna Brujic

The algorithmic self-assembly of shapes has been considered in several models of self-assembly. For the problem of \emph{shape construction}, we consider an extended version of the Two-Handed Tile Assembly Model (2HAM), which contains…

Computational Geometry · Computer Science 2016-08-18 Austin Luchsinger , Robert Schweller , Tim Wylie

Self-assembly is one of the most promising strategies for making functional materials at the nanoscale, yet new design principles for making self-limiting architectures, rather than spatially unlimited periodic lattice structures, are…

SLAM is a fundamental component of modern autonomous systems, providing robots and their operators with a deeper understanding of their environment. SLAM systems often encounter challenges due to the dynamic nature of robotic motion,…

Robotics · Computer Science 2025-04-29 Leon Davies , Baihua Li , Mohamad Saada , Simon Sølvsten , Qinggang Meng

DNA Self-Assembly has emerged as an interdisciplinary field with many intriguing applications such DNA bio-sensor, DNA circuits, DNA storage, drug delivery etc. Tile assembly model of DNA has been studied for various computational…

Emerging Technologies · Computer Science 2015-02-20 Shalin Shah , Parth Dave , Manish K Gupta

Self-assembly of complex and functional materials remains a grand challenge in soft material science. Efficient assembly depends on a delicate balance between thermodynamic and kinetic effects, requiring fine-tuning affinities and…

Soft Condensed Matter · Physics 2024-11-14 Wei-Shao Wei , Anthony Trubiano , Christian Sigl , Stefan Paquay , Hendrik Dietz , Michael F. Hagan , Seth Fraden

Self-assembly is a fundamental process by which supramolecular species form spontaneously from their components. This process is ubiquitous throughout the life chemistry and is central to biological information processing. Algorithms for…

Emerging Technologies · Computer Science 2012-07-06 Abhishek Chhajer , Manish K. Gupta , Sandeep Vasani , Jaley Dholakiya