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In this work we propose a generalization of Winfree's abstract Tile Assembly Model (aTAM) in which tile types are assigned rigid shapes, or geometries, along each tile face. We examine the number of distinct tile types needed to assemble…

Computational Geometry · Computer Science 2015-03-19 Bin Fu , Matthew J. Patitz , Robert T. Schweller , Bobby Sheline

We introduce a new DNA tile self-assembly model: the Surface Flexible Tile Assembly Model (SFTAM), where 2D tiles are placed on host 3D surfaces made of axis-parallel unit cubes glued together by their faces, called polycubes. The bonds are…

Discrete Mathematics · Computer Science 2023-06-19 Florent Becker , Shahrzad Heydarshahi

In this paper, we investigate shape-assembling power of a tile-based model of self-assembly called the Signal-Passing Tile Assembly Model (STAM). In this model, the glues that bind tiles together can be turned on and off by the binding…

Formal Languages and Automata Theory · Computer Science 2022-06-09 Andrew Alseth , Daniel Hader , Matthew J. Patitz

The 2-Handed Assembly Model (2HAM) is a tile-based self-assembly model in which, typically beginning from single tiles, arbitrarily large aggregations of static tiles combine in pairs to form structures. The Signal-passing Tile Assembly…

Emerging Technologies · Computer Science 2013-12-16 Tyler Fochtman , Jacob Hendricks , Jennifer E. Padilla , Matthew J. Patitz , Trent A. Rogers

We define the Reflexive Tile Assembly Model (RTAM), which is obtained from the abstract Tile Assembly Model (aTAM) by allowing tiles to reflect across their horizontal and/or vertical axes. We show that the class of directed temperature-1…

Computational Geometry · Computer Science 2015-03-13 Jacob Hendricks , Matthew J. Patitz , Trent A. Rogers

Perhaps the two most significant theoretical questions about the programming of self-assembling agents are: (1) necessary and sufficient conditions to produce a unique terminal assembly, and (2) error correction. We address both questions,…

Data Structures and Algorithms · Computer Science 2009-09-16 Aaron Sterling

Harnessing the intrinsic dynamics of physical systems for information processing opens new avenues for computation embodied in matter. Using simulations of a model system, we show that assemblies of DNA tiles capable of self-organizing into…

Soft Condensed Matter · Physics 2025-10-23 Tim E. Veenstra , René van Roij , Marjolein Dijkstra

We present a series of results related to mathematical models of self-assembling tiles and the impacts that three diverse properties have on their dynamics. We expand upon a series of prior results which showed that (1) the abstract Tile…

Computational Geometry · Computer Science 2019-10-10 Daniel Hader , Aaron Koch , Matthew J. Patitz , Michael Sharp

In this paper, we investigate the abilities of systems of self-assembling tiles which can each pass a constant number of signals to their immediate neighbors to create replicas of input shapes. Namely, we work within the Signal-passing Tile…

Emerging Technologies · Computer Science 2022-04-05 Andrew Alseth , Jacob Hendricks , Matthew J. Patitz , Trent A. Rogers

The Pattern self-Assembly Tile set Synthesis (PATS) problem, which arises in the theory of structured DNA self-assembly, is to determine a set of coloured tiles that, starting from a bordering seed structure, self-assembles to a given…

Emerging Technologies · Computer Science 2014-12-24 Mika Göös , Tuomo Lempiäinen , Eugen Czeizler , Pekka Orponen

The early promises of DNA computing to deliver a massively parallel architecture well-suited to computationally hard problems have so far been largely unkept. Indeed, it is probably fair to say that only toy problems have been addressed…

Cryptography and Security · Computer Science 2007-05-23 Olivier Pelletier , Andre Weimerskirch

We consider a model of algorithmic self-assembly of geometric shapes out of square Wang tiles studied in SODA 2010, in which there are two types of tiles (e.g., constructed out of DNA and RNA material) and one operation that destroys all…

Computational Complexity · Computer Science 2010-07-09 Erik D. Demaine , Matthew J. Patitz , Robert T. Schweller , Scott M. Summers

DNA self-assembly is an important tool that has a wide range of applications such as building nanostructures, the transport of target virotherapies, and nano-circuitry. Tools from graph theory can be used to encode the biological process of…

Combinatorics · Mathematics 2023-10-09 Cory Johnson , Andrew Lavengood-Ryan

Branched molecules of deoxyribonucleic acid (DNA) can self-assemble into nanostructures through complementary cohesive strand base pairing. The production of DNA nanostructures is valuable in targeted drug delivery and biomolecular…

Combinatorics · Mathematics 2022-03-15 D. Chloe Griffin , Jessica Sorrells

The Watson-Crick complementary properties of DNA make DNA a useful tool for the self-assembly of various target complexes. Concepts from graph theory can be used to model the self-assembling process in which the vertices of the graph…

Combinatorics · Mathematics 2023-02-28 Gabriel Lopez , Cory Johnson

In this paper we explore the power of geometry to overcome the limitations of non-cooperative self-assembly. We define a generalization of the abstract Tile Assembly Model (aTAM), such that a tile system consists of a collection of…

Emerging Technologies · Computer Science 2014-08-20 Sándor P. Fekete , Jacob Hendricks , Matthew J. Patitz , Trent A. Rogers , Robert T. Schweller

We propose a mathematical model of DNA self-assembly using 2D tiles to form 3D nanostructures. This is the first work to combine studies in self-assembly and nanotechnology in 3D, just as Rothemund and Winfree did in the 2D case. Our model…

Computational Complexity · Computer Science 2007-05-23 Ming-Yang Kao , Vijay Ramachandran

Recent advances enable the creation of nanoscale building blocks with complex geometries and interaction specificities for self-assembly. This nearly boundless design space necessitates design principles for defining the mutual interactions…

Soft Condensed Matter · Physics 2024-03-29 Daichi Hayakawa , Thomas E. Videbæk , Gregory M. Grason , W. Benjamin Rogers

The Pattern self-Assembly Tile set Synthesis (PATS) problem is to determine a set of coloured tiles that self-assemble to implement a given rectangular colour pattern. We give an exhaustive branch-and-bound algorithm to find tile sets of…

Data Structures and Algorithms · Computer Science 2015-03-13 Mika Göös , Pekka Orponen

In this paper we investigate the computational power of the polygonal tile assembly model (polygonal TAM) at temperature 1, i.e. in non-cooperative systems. The polygonal TAM is an extension of Winfree's abstract tile assembly model (aTAM)…

Computational Geometry · Computer Science 2015-08-20 Oscar Gilbert , Jacob Hendricks , Matthew J. Patitz , Trent A. Rogers