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Transient absorption and Raman scattering measurements on noble metal nanoparticles offer complimentary information on their vibrational modes and mechanical interactions with their surroundings. We have developed a comprehensive modeling…

Mesoscale and Nanoscale Physics · Physics 2024-10-29 Rachel Gelfand , Matthew Pelton

Scanning Electron Microscopes (SEMs) are widely renowned for their ability to analyze the surface structures of microscopic objects, offering the capability to capture highly detailed, yet only grayscale, images. To create more expressive…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Takuma Nishimura , Andreea Dogaru , Martin Oeggerli , Bernhard Egger

The availability of open-source molecular simulation software packages allows scientists and engineers to focus on running and analyzing simulations without having to write, parallelize, and validate their own simulation software. While…

Computational Physics · Physics 2025-10-03 Simon Gravelle , Cecilia M. S. Alvares , Jacob R. Gissinger , Axel Kohlmeyer

Characterization of the electronic band structure of solid state materials is routinely performed using photoemission spectroscopy. Recent advancements in short-wavelength light sources and electron detectors give rise to multidimensional…

We demonstrate an electro-optic wide-field method to enable fluorescence lifetime microscopy (FLIM) with high throughput and single-molecule sensitivity. Resonantly driven Pockels cells are used to efficiently gate images at 39 MHz,…

Optics · Physics 2021-09-23 Adam J. Bowman , Mark A. Kasevich

With the ever growing popularity of integral field unit (IFU) spectroscopy, countless observations are being performed over multiple object systems such as blank fields and galaxy clusters. With this, an increasing amount of time is being…

Astrophysics of Galaxies · Physics 2018-12-18 Alex Griffiths , Christopher J. Conselice

FOS, which means light in Greek, is an open-source program for Fast Optical Spectrum calculations of nanoparticle media. This program takes the material properties and a description of the system as input, and outputs the spectral response…

Computational Physics · Physics 2024-09-04 Daniel Carne , Joseph Peoples , Ziqi Guo , Dudong Feng , Zherui Han , Xiaojie Liu , Xiulin Ruan

Label-free vibrational imaging by stimulated Raman scattering (SRS) provides unprecedented insight into real-time chemical distributions in living systems. Specifically, SRS in the fingerprint region can resolve multiple chemicals in a…

Improving the resolution of fluorescence microscopy beyond the diffraction limit can be achievedby acquiring and processing multiple images of the sample under different illumination conditions.One of the simplest techniques, Random…

Background-free fluorescence detection in multidimensional electronic spectroscopy promises high sensitivity compared to conventional approaches. Here we explore the sensitivity limits of multidimensional electronic spectroscopy. We present…

Chemical Physics · Physics 2022-10-18 Amitav Sahu , Vivek N. Bhat , Sanjoy Patra , Vivek Tiwari

Aims. We provide an easy-to-use full-spectrum fitting package and explore its applications to (i) the determination of the stellar atmospheric parameters and (ii) the study of the history of stellar populations. Methods. We developed ULySS,…

Instrumentation and Methods for Astrophysics · Physics 2015-05-13 Mina Koleva , Philippe Prugniel , Antoine Bouchard , Yue Wu

SMART is a software package written in IDL to reduce and analyze Spitzer data from all four modules of the Infrared Spectrograph, including the peak-up arrays. The software is designed to make full use of the ancillary files generated in…

Frequency comb spectroscopy provides broadband access to molecular fingerprints with mode-defined spectral resolution. However, its deployment in non-cooperative gas sensing remains challenging because conventional implementations require…

Atomic-resolution imaging with scanning transmission electron microscopy is a powerful tool for characterizing the nanoscale structure of materials, in particular features such as defects, local strains, and symmetry-breaking distortions.…

Super-resolution microscopy has catalyzed valuable insights into the sub-cellular, mechanistic details of many different biological processes across a wide range of cell types. Fluorescence polarization spectroscopy tools have also enabled…

Biological Physics · Physics 2023-01-25 Jack W Shepherd , Alex L Payne-Dwyer , Ji-Eun Lee , Aisha Syeda , Mark C Leake

We present a new scheme for performing optical spectroscopy on single molecules. A glass capillary with a diameter of 600 nm filled with an organic crystal tightly guides the excitation light and provides a maximum spontaneous emission…

Direct optical frequency Comb Spectroscopy (DCS) is proving to be a fundamental tool in many areas of science and technology thanks to its unique performance in terms of ultra-broadband, high-speed detection and frequency accuracy, allowing…

Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the universal…

Orchestrating parametric fitting of multicomponent spectra at scale is an essential yet underappreciated task in high-throughput quantification of materials and chemical composition. To automate the annotation process for spectroscopic and…

Materials Science · Physics 2021-03-30 Rui Patrick Xian , Ralph Ernstorfer , Philipp Michael Pelz

We demonstrate a robust fiber-optics-based fluorescence detector, fully integrated on an atom chip, which detects single atoms propagating in a guide with 66% efficiency. We characterize the detector performance and the atom flux by…

Quantum Physics · Physics 2009-03-24 Dennis Heine , Marco Wilzbach , Thomas Raub , Björn Hessmo , Jörg Schmiedmayer