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To date, developing a good model for early intensive care unit (ICU) mortality prediction is still challenging. This paper presents a patient based predictive modeling framework (PPMF) to improve the performance of ICU mortality prediction…

Machine Learning · Computer Science 2017-05-02 Mohammad Amin Morid , Olivia R. Liu Sheng , Samir Abdelrahman

Principal Component Analysis (PCA) minimizes the reconstruction error given a class of linear models of fixed component dimensionality. Probabilistic PCA adds a probabilistic structure by learning the probability distribution of the PCA…

Machine Learning · Computer Science 2022-09-20 Vanessa Böhm , Uroš Seljak

Subject-specific cardiovascular models rely on parameter estimation using measurements such as 4D Flow MRI data. However, acquiring high-resolution, high-fidelity functional flow data is costly and taxing for the patient. As a result, there…

Medical Physics · Physics 2025-12-09 Miriam Löcke , Ahmed Attia , Dariusz Ucínski , Cristóbal Bertoglio

Learning neural operators on heterogeneous and irregular geometries remains a fundamental challenge, as existing approaches typically rely on structured discretisations or explicit mappings to a shared reference domain. We propose a unified…

Current deep learning-based manifold learning algorithms such as the variational autoencoder (VAE) require fully sampled data to learn the probability density of real-world datasets. Once learned, the density can be used for a variety of…

Image and Video Processing · Electrical Eng. & Systems 2021-12-13 Qing Zou , Abdul Haseeb Ahmed , Prashant Nagpal , Sarv Priya , Rolf Schulte , Mathews Jacob

We developed a new approach for the analysis of physiological time series. An iterative convolution filter is used to decompose the time series into various components. Statistics of these components are extracted as features to…

Machine Learning · Computer Science 2015-04-24 Dong Mao , Yang Wang , Qiang Wu

We consider an inverse problem involving the reconstruction of the solution to a nonlinear partial differential equation (PDE) with unknown boundary conditions. Instead of direct boundary data, we are provided with a large dataset of…

Numerical Analysis · Mathematics 2025-07-30 Erik Burman , Mats G. Larson , Karl Larsson , Carl Lundholm

Physics-informed neural networks have emerged as a powerful tool in the scientific machine learning community, with applications to both forward and inverse problems. While they have shown considerable empirical success, significant…

Optimization and Control · Mathematics 2025-12-11 Federica Caforio , Martin Holler , Matthias Höfler

Optimization-based state estimation is useful for nonlinear or constrained dynamic systems for which few general methods with established properties are available. The two fundamental forms are moving horizon estimation (MHE) which uses the…

Optimization and Control · Mathematics 2017-09-27 Wuhua Hu

Forward and inverse models are used throughout different engineering fields to predict and understand the behaviour of systems and to find parameters from a set of observations. These models use root-finding and minimisation techniques…

Computational Engineering, Finance, and Science · Computer Science 2023-08-08 Preslav Aleksandrov

Finite element model updating of a structure made of linear elastic materials is based on the solution of a minimization problem. The goal is to find some unknown parameters of the finite element model (elastic moduli, mass densities,…

Computational Engineering, Finance, and Science · Computer Science 2021-02-24 Maria Girardi , Cristina Padovani , Daniele Pellegrini , Leonardo Robol

Background: The complete event fission simulation code FREYA is used to study correlations in fission. To make the best possible simulations, FREYA one must find the optimized values of the five physics-based parameters which characterize…

Nuclear Theory · Physics 2019-01-10 Jackson Van Dyke , Lee Bernstein , Ramona Vogt

We present an approach for synthesising observational data with elastodynamic finite element models by extending the statistical finite element method (statFEM) framework. The proposed formulation adopts a Bayesian filtering approach to…

Numerical Analysis · Mathematics 2026-04-15 Igor Kavrakov , Yaswanth Sai Jetti , Ahmet Oguzhan Yuksel , Fehmi Cirak

This paper presents a two-step Bayesian framework for the estimation of the intrinsic single crystal elastic stiffness parameters from the measurements of spherical indentation stress-strain responses in multiple individual grains of a…

Computational Physics · Physics 2019-05-07 Andrew Castillo , Surya R. Kalidindi

Personalized virtual heart models have demonstrated increasing potential for clinical use, although the estimation of their parameters given patient-specific data remain a challenge. Traditional physics-based modeling approaches are…

Signal Processing · Electrical Eng. & Systems 2024-03-26 Xiajun Jiang , Sumeet Vadhavkar , Yubo Ye , Maryam Toloubidokhti , Ryan Missel , Linwei Wang

The numerical tools to simulate the bidomain model in cardiac electrophysiology are constantly developing due to the great clinical interest and scientific advances in mathematical models and computational power. The bidomain model consists…

Numerical Analysis · Mathematics 2025-11-03 Gopika P B , Peter Bastian , Nagaiah Chamakuri

Numerical modeling of viscoelastic properties is critical to developing the structure-property relationship of polymer nanocomposites. While it is recognized that the altered polymer region near filler particles, the interphase,…

Materials Science · Physics 2018-11-16 Xiaolin Li , Min Zhang , Yixing Wang , Min Zhang , Aditya Prasad , Wei Chen , Linda Schadler , L. Catherine Brinson

In this paper, an important discovery has been found for nonconforming immersed finite element (IFE) methods using the integral values on edges as degrees of freedom for solving elliptic interface problems. We show that those IFE methods…

Numerical Analysis · Mathematics 2023-05-17 Haifeng Ji , Feng Wang , Jinru Chen , Zhilin Li

Fiber-reinforced soft biological tissues are typically modeled as hyperelastic, anisotropic, and nearly incompressible materials. To enforce incompressibility a multiplicative split of the deformation gradient into a volumetric and an…

Numerical Analysis · Mathematics 2022-04-13 Elias Karabelas , Matthias A. F. Gsell , Gundolf Haase , Gernot Plank , Christoph M. Augustin

Cardiovascular diseases, particularly arrhythmias, remain a leading global cause of mortality, necessitating continuous monitoring via the Internet of Medical Things (IoMT). However, state-of-the-art deep learning approaches often impose…

Machine Learning · Computer Science 2026-01-05 Moirangthem Tiken Singh , Manibhushan Yaikhom