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Hippocampus segmentation plays a key role in diagnosing various brain disorders such as Alzheimer's disease, epilepsy, multiple sclerosis, cancer, depression and others. Nowadays, segmentation is still mainly performed manually by…

Image and Video Processing · Electrical Eng. & Systems 2020-05-15 Diedre Carmo , Bruna Silva , Clarissa Yasuda , Letícia Rittner , Roberto Lotufo

Improving controllability or the ability to manipulate one or more attributes of the generated data has become a topic of interest in the context of deep generative models of music. Recent attempts in this direction have relied on learning…

Sound · Computer Science 2021-08-04 Ashis Pati , Alexander Lerch

Sparse Autoencoders (SAEs) have emerged as a promising approach for interpreting neural network representations by learning sparse, human-interpretable features from dense activations. We investigate whether incorporating variational…

Machine Learning · Computer Science 2025-10-03 Zachary Baker , Yuxiao Li

We propose an algorithm, guided variational autoencoder (Guided-VAE), that is able to learn a controllable generative model by performing latent representation disentanglement learning. The learning objective is achieved by providing…

Computer Vision and Pattern Recognition · Computer Science 2020-04-06 Zheng Ding , Yifan Xu , Weijian Xu , Gaurav Parmar , Yang Yang , Max Welling , Zhuowen Tu

Layout design with complex constraints is a challenging problem to solve due to the non-uniqueness of the solution and the difficulties in incorporating the constraints into the conventional optimization-based methods. In this paper, we…

Signal Processing · Electrical Eng. & Systems 2018-06-11 Yujie Zhang , Wenjing Ye

Hippocampus segmentation on magnetic resonance imaging is of key importance for the diagnosis, treatment decision and investigation of neuropsychiatric disorders. Automatic segmentation is an active research field, with many recent models…

Image and Video Processing · Electrical Eng. & Systems 2021-02-12 Diedre Carmo , Bruna Silva , Clarissa Yasuda , Letícia Rittner , Roberto Lotufo

Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Fangqi Cheng , Yingying Zhao , Xiaochen Yang

Variational autoencoders (VAEs) have recently been used for unsupervised disentanglement learning of complex density distributions. Numerous variants exist to encourage disentanglement in latent space while improving reconstruction.…

Machine Learning · Statistics 2022-06-10 Kenneth Ezukwoke , Anis Hoayek , Mireille Batton-Hubert , Xavier Boucher

Brain aging involves structural and functional changes and therefore serves as a key biomarker for brain health. Combining structural magnetic resonance imaging (sMRI) and functional magnetic resonance imaging (fMRI) has the potential to…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Abd Ur Rehman , Azka Rehman , Muhammad Usman , Abdullah Shahid , Sung-Min Gho , Aleum Lee , Tariq M. Khan , Imran Razzak

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

Automatic segmentation of brain abnormalities is challenging, as they vary considerably from one pathology to another. Current methods are supervised and require numerous annotated images for each pathology, a strenuous task. To tackle…

Image and Video Processing · Electrical Eng. & Systems 2021-01-27 Benjamin Lambert , Maxime Louis , Senan Doyle , Florence Forbes , Michel Dojat , Alan Tucholka

Objective: fMRI and derived measures such as functional connectivity (FC) have been used to predict brain age, general fluid intelligence, psychiatric disease status, and preclinical neurodegenerative disease. However, it is not always…

Quantitative Methods · Quantitative Biology 2024-05-14 Anton Orlichenko , Gang Qu , Ziyu Zhou , Anqi Liu , Hong-Wen Deng , Zhengming Ding , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

Simultaneous recordings from thousands of neurons across multiple brain areas reveal rich mixtures of activity that are shared between regions and dynamics that are unique to each region. Existing alignment or multi-view methods neglect…

Machine Learning · Computer Science 2025-10-24 Ram Dyuthi Sristi , Sowmya Manojna Narasimha , Jingya Huang , Alice Despatin , Simon Musall , Vikash Gilja , Gal Mishne

Learning rich data representations from unlabeled data is a key challenge towards applying deep learning algorithms in downstream tasks. Several variants of variational autoencoders (VAEs) have been proposed to learn compact data…

Computer Vision and Pattern Recognition · Computer Science 2024-01-11 Pan Xiao , Peijie Qiu , Sungmin Ha , Abdalla Bani , Shuang Zhou , Aristeidis Sotiras

We decompose the evidence lower bound to show the existence of a term measuring the total correlation between latent variables. We use this to motivate our $\beta$-TCVAE (Total Correlation Variational Autoencoder), a refinement of the…

Machine Learning · Computer Science 2019-04-24 Ricky T. Q. Chen , Xuechen Li , Roger Grosse , David Duvenaud

Meaningful and simplified representations of neural activity can yield insights into how and what information is being processed within a neural circuit. However, without labels, finding representations that reveal the link between the…

Machine Learning · Computer Science 2021-11-04 Ran Liu , Mehdi Azabou , Max Dabagia , Chi-Heng Lin , Mohammad Gheshlaghi Azar , Keith B. Hengen , Michal Valko , Eva L. Dyer

The integration of different imaging modalities, such as structural, diffusion tensor, and functional magnetic resonance imaging, with deep learning models has yielded promising outcomes in discerning phenotypic characteristics and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Zhiyuan Li , Hailong Li , Anca L. Ralescu , Jonathan R. Dillman , Mekibib Altaye , Kim M. Cecil , Nehal A. Parikh , Lili He

Disentangled generative models map a latent code vector to a target space, while enforcing that a subset of the learned latent codes are interpretable and associated with distinct properties of the target distribution. Recent advances have…

Machine Learning · Computer Science 2020-08-10 Zinan Lin , Kiran Koshy Thekumparampil , Giulia Fanti , Sewoong Oh

Most of the temporal lobe epilepsy detection approaches are based on hippocampus deformation and use complicated features, resulting, detection is done with complicated features extraction and pre-processing task. In this paper, a new…

Computer Vision and Pattern Recognition · Computer Science 2016-12-30 Zohreh Kohan , Hamidreza Farhidzadeh , Reza Azmi , Behrouz Gholizadeh

Heterogeneity of brain diseases is a challenge for precision diagnosis/prognosis. We describe and validate Smile-GAN (SeMI-supervised cLustEring-Generative Adversarial Network), a novel semi-supervised deep-clustering method, which dissects…