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The paper presents the application of Variational Autoencoders (VAE) for data dimensionality reduction and explorative analysis of mass spectrometry imaging data (MSI). The results confirm that VAEs are capable of detecting the patterns…

Quantitative Methods · Quantitative Biology 2017-08-25 Paolo Inglese , James L. Alexander , Anna Mroz , Zoltan Takats , Robert Glen

Unsupervised learning of disentangled representations is an open problem in machine learning. The Disentanglement-PyTorch library is developed to facilitate research, implementation, and testing of new variational algorithms. In this…

Machine Learning · Computer Science 2019-12-12 Amir H. Abdi , Purang Abolmaesumi , Sidney Fels

Several factors contribute to the appearance of an object in a visual scene, including pose, illumination, and deformation, among others. Each factor accounts for a source of variability in the data, while the multiplicative interactions of…

Computer Vision and Pattern Recognition · Computer Science 2019-02-26 Mengjiao Wang , Zhixin Shu , Shiyang Cheng , Yannis Panagakis , Dimitris Samaras , Stefanos Zafeiriou

We propose to apply non-linear representation learning to voxelwise rs-fMRI data. Learning the non-linear representations is done using a variational autoencoder (VAE). The VAE is trained on voxelwise rs-fMRI data and performs non-linear…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 Eloy Geenjaar , Tonya White , Vince Calhoun

Missing input sequences are common in medical imaging data, posing a challenge for deep learning models reliant on complete input data. In this work, inspired by MultiMAE [2], we develop a masked autoencoder (MAE) paradigm for multi-modal,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Ayhan Can Erdur , Christian Beischl , Daniel Scholz , Jiazhen Pan , Benedikt Wiestler , Daniel Rueckert , Jan C Peeken

Background: Deep learning has demonstrated significant potential for automated brain metastases (BM) segmentation; however, models trained at a singular institution often exhibit suboptimal performance at various sites due to disparities in…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Yuchen Yang , Shuangyang Zhong , Haijun Yu , Langcuomu Suo , Hongbin Han , Florian Putz , Yixing Huang

Vascular remodelling is inherent to the pathogenesis of many diseases including cancer, neurodegeneration, fibrosis, hypertension, and diabetes. In this paper, a new susceptibility-contrast based MRI approach is established to analyse…

Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology. However, whole-slide imaging (WSI) is a complex computer vision in…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Richard J. Chen , Rahul G. Krishnan

Alzheimer's disease (AD) is an incurable neurodegenerative condition leading to cognitive and functional deterioration. Given the lack of a cure, prompt and precise AD diagnosis is vital, a complex process dependent on multiple factors and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Guangqian Yang , Kangrui Du , Zhihan Yang , Ye Du , Yongping Zheng , Shujun Wang

Intelligent behaviour in the real-world requires the ability to acquire new knowledge from an ongoing sequence of experiences while preserving and reusing past knowledge. We propose a novel algorithm for unsupervised representation learning…

In the contrastive analysis (CA) setting, machine learning practitioners are specifically interested in discovering patterns that are enriched in a target dataset as compared to a background dataset generated from sources of variation…

Machine Learning · Computer Science 2022-02-23 Ethan Weinberger , Nicasia Beebe-Wang , Su-In Lee

Medical datasets and especially biobanks, often contain extensive tabular data with rich clinical information in addition to images. In practice, clinicians typically have less data, both in terms of diversity and scale, but still wish to…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Paul Hager , Martin J. Menten , Daniel Rueckert

GAN-based facial attribute editing is widely used in virtual avatars and social media but often suffers from attribute entanglement, where modifying one face attribute unintentionally alters others. While supervised disentangled…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Xuan Cui , Yunfei Zhao , Bo Liu , Wei Duan , Xingrong Fan

In this tutorial, we explore Variational Autoencoders (VAEs), an essential framework for unsupervised learning, particularly suited for high-dimensional datasets such as neuroimaging. By integrating deep learning with Bayesian inference,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 C. Vázquez-García , F. J. Martínez-Murcia , F. Segovia Román , Juan M. Górriz Sáez

Self-supervised learning methods based on image patch reconstruction have witnessed great success in training auto-encoders, whose pre-trained weights can be transferred to fine-tune other downstream tasks of image understanding. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Junjia Huang , Haofeng Li , Guanbin Li , Xiang Wan

Disentangled sequential autoencoders (DSAEs) represent a class of probabilistic graphical models that describes an observed sequence with dynamic latent variables and a static latent variable. The former encode information at a frame rate…

Sound · Computer Science 2022-06-16 Yin-Jyun Luo , Sebastian Ewert , Simon Dixon

Reliably modeling normality and differentiating abnormal appearances from normal cases is a very appealing approach for detecting pathologies in medical images. A plethora of such unsupervised anomaly detection approaches has been made in…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Christoph Baur , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Machine learning analysis of longitudinal neuroimaging data is typically based on supervised learning, which requires a large number of ground-truth labels to be informative. As ground-truth labels are often missing or expensive to obtain…

Machine Learning · Computer Science 2021-06-29 Qingyu Zhao , Zixuan Liu , Ehsan Adeli , Kilian M. Pohl

Variational Autoencoders (VAEs) constitute a crucial component of neural symbolic music generation, among which some works have yielded outstanding results and attracted considerable attention. Nevertheless, previous VAEs still encounter…

Sound · Computer Science 2024-01-17 Zhiwei Lin , Jun Chen , Boshi Tang , Binzhu Sha , Jing Yang , Yaolong Ju , Fan Fan , Shiyin Kang , Zhiyong Wu , Helen Meng

The Variational Autoencoder (VAE) is a powerful deep generative model that is now extensively used to represent high-dimensional complex data via a low-dimensional latent space learned in an unsupervised manner. In the original VAE model,…

Sound · Computer Science 2021-06-15 Xiaoyu Bie , Laurent Girin , Simon Leglaive , Thomas Hueber , Xavier Alameda-Pineda
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