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Related papers: Disentangling Hippocampal Shape Variations: A Stud…

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The use of deep learning to undertake shape analysis of the complexities of the human head holds great promise. However, there have traditionally been a number of barriers to accurate modelling, especially when operating on both a global…

Understanding the structure of complex, nonstationary, high-dimensional time-evolving signals is a central challenge in scientific data analysis. In many domains, such as speech and biomedical signal processing, the ability to learn…

Machine Learning · Computer Science 2026-01-13 Ioannis Ziogas , Aamna Al Shehhi , Ahsan H. Khandoker , Leontios J. Hadjileontiadis

Brain network analysis is a useful approach to studying human brain disorders because it can distinguish patients from healthy people by detecting abnormal connections. Due to the complementary information from multiple modal neuroimages,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Qiankun Zuo , Yanfei Zhu , Libin Lu , Zhi Yang , Yuhui Li , Ning Zhang

Deep learning (DL) methods where interpretability is intrinsically considered as part of the model are required to better understand the relationship of clinical and imaging-based attributes with DL outcomes, thus facilitating their use in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-13 Irem Cetin , Maialen Stephens , Oscar Camara , Miguel Angel Gonzalez Ballester

Disentangling pathological changes from physiological aging in 3D medical shapes is crucial for developing interpretable biomarkers and patient stratification. However, this separation is challenging when diagnosis labels are limited or…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Jakaria Rabbi , Nilanjan Ray , Dana Cobzas

Variational autoencoders (VAEs) are among leading approaches to address the problem of learning disentangled representations. Typically a single VAE is used and disentangled representations are sought within its single continuous latent…

Machine Learning · Statistics 2026-04-02 Veranika Boukun , Jörg Lücke

Learning a disentangled, interpretable, and structured latent representation in 3D generative models of faces and bodies is still an open problem. The problem is particularly acute when control over identity features is required. In this…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Simone Foti , Bongjin Koo , Danail Stoyanov , Matthew J. Clarkson

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

Machine Learning · Computer Science 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

The hippocampus is one of the most studied neuroanatomical structures due to its involvement in attention, learning, and memory as well as its atrophy in ageing, neurological, and psychiatric diseases. Hippocampal shape changes, however,…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Kersten Diers , Hannah Baumeister , Frank Jessen , Emrah Düzel , David Berron , Martin Reuter

Limited amount of labelled training data are a common problem in medical imaging. This makes it difficult to train a well-generalised model and therefore often leads to failure in unknown domains. Hippocampus segmentation from magnetic…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 John Kalkhof , Camila González , Anirban Mukhopadhyay

A variational autoencoder (VAE) is a probabilistic machine learning framework for posterior inference that projects an input set of high-dimensional data to a lower-dimensional, latent space. The latent space learned with a VAE offers…

Machine Learning · Computer Science 2022-11-16 Rafael Pastrana

Learning Interpretable representation in medical applications is becoming essential for adopting data-driven models into clinical practice. It has been recently shown that learning a disentangled feature representation is important for a…

Machine Learning · Computer Science 2019-04-19 Mhd Hasan Sarhan , Abouzar Eslami , Nassir Navab , Shadi Albarqouni

One major challenge of disentanglement learning with variational autoencoders is the trade-off between disentanglement and reconstruction fidelity. Previous studies, which increase the information bottleneck during training, tend to lose…

Machine Learning · Computer Science 2023-10-05 Jiantao Wu , Shentong Mo , Xiang Yang , Muhammad Awais , Sara Atito , Xingshen Zhang , Lin Wang , Xiang Yang

High-dimensional clinical data have become invaluable resources for genetic studies, due to their accessibility in biobank-scale datasets and the development of high performance modeling techniques especially using deep learning. Recent…

Machine Learning · Computer Science 2023-07-19 Taedong Yun

Mapping of human brain structural connectomes via diffusion MRI offers a unique opportunity to understand brain structural connectivity and relate it to various human traits, such as cognition. However, head displacement during image…

Neurons and Cognition · Quantitative Biology 2024-09-13 Yizi Zhang , Meimei Liu , Zhengwu Zhang , David Dunson

In this paper, we propose a novel model called Learnable VAE (L-VAE), which learns a disentangled representation together with the hyperparameters of the cost function. L-VAE can be considered as an extension of \b{eta}-VAE, wherein the…

Machine Learning · Computer Science 2025-07-04 Hazal Mogultay Ozcan , Sinan Kalkan , Fatos T. Yarman-Vural

Elucidating the functional mechanisms of the primary visual cortex (V1) remains a fundamental challenge in systems neuroscience. Current computational models face two critical limitations, namely the challenge of cross-modal integration…

Neurons and Cognition · Quantitative Biology 2024-12-20 Yu Zhu , Bo Lei , Chunfeng Song , Wanli Ouyang , Shan Yu , Tiejun Huang

Despite advances in deep learning for estimating brain age from structural MRI data, incorporating functional MRI data is challenging due to its complex structure and the noisy nature of functional connectivity measurements. To address…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Muhammad Usman , Azka Rehman , Abdullah Shahid , Abd Ur Rehman , Sung-Min Gho , Aleum Lee , Tariq M. Khan , Imran Razzak

Obesity is a common issue in modern societies today that can lead to various diseases and significantly reduced quality of life. Currently, research has been conducted to investigate resting state EEG (electroencephalogram) signals with an…

Machine Learning · Computer Science 2023-02-03 Yuan Yue , Jeremiah D. Deng , Dirk De Ridder , Patrick Manning , Divya Adhia

Self-supervised disentangled representation learning is a critical task in sequence modeling. The learnt representations contribute to better model interpretability as well as the data generation, and improve the sample efficiency for…

Machine Learning · Computer Science 2021-10-26 Junwen Bai , Weiran Wang , Carla Gomes
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