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We propose a Deep learning-based weak label learning method for analyzing whole slide images (WSIs) of Hematoxylin and Eosin (H&E) stained tumor tissue not requiring pixel-level or tile-level annotations using Self-supervised pre-training…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Yoni Schirris , Efstratios Gavves , Iris Nederlof , Hugo Mark Horlings , Jonas Teuwen

Generating realistic 3D Human-Human Interaction (HHI) requires coherent modeling of the physical plausibility of the agents and their interaction semantics. Existing methods compress all motion information into a single latent…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Zichen Geng , Zeeshan Hayder , Bo Miao , Jian Liu , Wei Liu , Ajmal Mian

The variational autoencoder (VAE) is a popular deep latent variable model used to analyse high-dimensional datasets by learning a low-dimensional latent representation of the data. It simultaneously learns a generative model and an…

Machine Learning · Computer Science 2023-11-21 Mine Öğretir , Siddharth Ramchandran , Dimitrios Papatheodorou , Harri Lähdesmäki

High-dimensional neuroimaging data presents challenges for assessing neurodegenerative diseases due to complex non-linear relationships. Variational Autoencoders (VAEs) can encode scans into lower-dimensional latent spaces capturing…

Purpose: Different Magnetic resonance imaging (MRI) modalities of the same anatomical structure are required to present different pathological information from the physical level for diagnostic needs. However, it is often difficult to…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Yuchen Fei , Bo Zhan , Mei Hong , Xi Wu , Jiliu Zhou , Yan Wang

As we enter the era of machine learning characterized by an overabundance of data, discovery, organization, and interpretation of the data in an unsupervised manner becomes a critical need. One promising approach to this endeavour is the…

Machine Learning · Computer Science 2022-10-24 Vaishnavi Patil , Matthew Evanusa , Joseph JaJa

Major depressive disorder (MDD) is a common neuropsychiatric condition whose accurate diagnosis from resting-state functional magnetic resonance imaging (rs-fMRI) remains difficult. Dynamic functional connectivity (DFC) captures…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Muhammad Asif Hasan , Yanming Zhu , Xuefei Yin , Alan Wee-Chung Liew

Recently, the standard variational autoencoder has been successfully used to learn a probabilistic prior over speech signals, which is then used to perform speech enhancement. Variational autoencoders have then been conditioned on a label…

Audio and Speech Processing · Electrical Eng. & Systems 2022-01-04 Guillaume Carbajal , Julius Richter , Timo Gerkmann

Self-supervised learning (SSL) has drawn increasing attention in histopathological image analysis in recent years. Compared to contrastive learning which is troubled with the false negative problem, i.e., semantically similar images are…

Computer Vision and Pattern Recognition · Computer Science 2023-05-30 Yang Luo , Zhineng Chen , Shengtian Zhou , Xieping Gao

Although Digital Subtraction Angiography (DSA) is the most important imaging for visualizing cerebrovascular anatomy, its interpretation by clinicians remains difficult. This is particularly true when treating arteriovenous malformations…

Image and Video Processing · Electrical Eng. & Systems 2024-02-16 Kathleen Baur , Xin Xiong , Erickson Torio , Rose Du , Parikshit Juvekar , Reuben Dorent , Alexandra Golby , Sarah Frisken , Nazim Haouchine

Estimation of uncertainty in deep learning models is of vital importance, especially in medical imaging, where reliance on inference without taking into account uncertainty could lead to misdiagnosis. Recently, the probabilistic Variational…

Machine Learning · Computer Science 2020-10-20 Haleh Akrami , Anand A. Joshi , Sergul Aydore , Richard M. Leahy

Acquisition differences across sites, scanners, and protocols in dMRI introduce variability that complicates structural connectome analysis. This motivates deep learning models that can represent high-dimensional connectomes in a…

In many data analysis tasks, it is beneficial to learn representations where each dimension is statistically independent and thus disentangled from the others. If data generating factors are also statistically independent, disentangled…

Machine Learning · Statistics 2019-12-12 Harshvardhan Sikka , Weishun Zhong , Jun Yin , Cengiz Pehlevan

Brain atrophy is an important biomarker for monitoring neurodegeneration and disease progression in conditions such as multiple sclerosis (MS). An accurate and robust quantitative measurement of brain volume change is paramount for…

Quantitative Methods · Quantitative Biology 2023-02-09 Geng Zhan , Dongang Wang , Mariano Cabezas , Lei Bai , Kain Kyle , Wanli Ouyang , Michael Barnett , Chenyu Wang

We present a novel method for constructing Variational Autoencoder (VAE). Instead of using pixel-by-pixel loss, we enforce deep feature consistency between the input and the output of a VAE, which ensures the VAE's output to preserve the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Xianxu Hou , Linlin Shen , Ke Sun , Guoping Qiu

Latent variable models such as the Variational Auto-Encoder (VAE) have become a go-to tool for analyzing biological data, especially in the field of single-cell genomics. One remaining challenge is the interpretability of latent variables…

Genomics · Quantitative Biology 2023-02-20 Romain Lopez , Nataša Tagasovska , Stephen Ra , Kyunghyn Cho , Jonathan K. Pritchard , Aviv Regev

Human readers can accurately count how many letters are in a word (e.g., 7 in ``buffalo''), remove a letter from a given position (e.g., ``bufflo'') or add a new one. The human brain of readers must have therefore learned to disentangle…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Bruno Bianchi , Aakash Agrawal , Stanislas Dehaene , Emmanuel Chemla , Yair Lakretz

The increasing availability of electrocardiogram (ECG) data has motivated the use of data-driven models for automating various clinical tasks based on ECG data. The development of subject-specific models are limited by the cost and…

Machine Learning · Computer Science 2018-08-07 Prashnna K Gyawali , B. Milan Horacek , John L. Sapp , Linwei Wang

Disentangled encoding is an important step towards a better representation learning. However, despite the numerous efforts, there still is no clear winner that captures the independent features of the data in an unsupervised fashion. In…

Machine Learning · Computer Science 2019-11-28 Amir H. Abdi , Purang Abolmaesumi , Sidney Fels

Current deep learning-based manifold learning algorithms such as the variational autoencoder (VAE) require fully sampled data to learn the probability density of real-world datasets. Once learned, the density can be used for a variety of…

Image and Video Processing · Electrical Eng. & Systems 2021-12-13 Qing Zou , Abdul Haseeb Ahmed , Prashant Nagpal , Sarv Priya , Rolf Schulte , Mathews Jacob
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