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Medical AI algorithms can often experience degraded performance when evaluated on previously unseen sites. Addressing cross-site performance disparities is key to ensuring that AI is equitable and effective when deployed on diverse patient…

Machine Learning · Computer Science 2021-11-17 Eric Wu , Kevin Wu , James Zou

This research presents an innovative approach to cancer diagnosis and prediction using explainable Artificial Intelligence (XAI) and deep learning techniques. With cancer causing nearly 10 million deaths globally in 2020, early and accurate…

Artificial Intelligence · Computer Science 2024-12-24 Badaru I. Olumuyiwa , The Anh Han , Zia U. Shamszaman

Explainable Artificial Intelligence (XAI) addresses the growing need for transparency and interpretability in AI systems, enabling trust and accountability in decision-making processes. This book offers a comprehensive guide to XAI,…

Pneumonia is a lung infection that causes 15% of childhood mortality, over 800,000 children under five every year, all over the world. This pathology is mainly caused by viruses or bacteria. X-rays imaging analysis is one of the most used…

Image and Video Processing · Electrical Eng. & Systems 2021-06-07 Helena Liz , Manuel Sánchez-Montañés , Alfredo Tagarro , Sara Domínguez-Rodríguez , Ron Dagan , David Camacho

Objective. This paper presents an overview of generalizable and explainable artificial intelligence (XAI) in deep learning (DL) for medical imaging, aimed at addressing the urgent need for transparency and explainability in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Ahmad Chaddad , Yan Hu , Yihang Wu , Binbin Wen , Reem Kateb

Explainable Artificial Intelligence (XAI) is an emerging research topic of machine learning aimed at unboxing how AI systems' black-box choices are made. This research field inspects the measures and models involved in decision-making and…

Artificial Intelligence · Computer Science 2021-02-04 Guang Yang , Qinghao Ye , Jun Xia

Pneumothorax, a collapsed or dropped lung, is a fatal condition typically detected on a chest X-ray by an experienced radiologist. Due to shortage of such experts, automated detection systems based on deep neural networks have been…

Image and Video Processing · Electrical Eng. & Systems 2020-07-31 Antonio Sze-To , Hamid Tizhoosh

Deep learning (DL) models have been popular due to their ability to learn directly from the raw data in an end-to-end paradigm, alleviating the concern of a separate error-prone feature extraction phase. Recent DL-based neuroimaging studies…

Machine Learning · Computer Science 2023-07-20 Md. Mahfuzur Rahman , Vince D. Calhoun , Sergey M. Plis

The increasing use of Machine Learning (ML) in sensitive domains such as healthcare, finance, and public policy has raised concerns about the transparency of automated decisions. Explainable AI (XAI) addresses this by clarifying how models…

Artificial Intelligence · Computer Science 2026-02-13 Natalia Abarca , Andrés Carvallo , Claudia López Moncada , Felipe Bravo-Marquez

Ensuring transparency and trust in AI-driven public health and biomedical sciences systems requires more than accurate predictions-it demands explanations that are clear, contextual, and socially accountable. While explainable AI (XAI) has…

Artificial Intelligence · Computer Science 2025-07-30 Bahar İlgen , Akshat Dubey , Georges Hattab

Both humans and machine learning models learn from experience, particularly in safety- and reliability-critical domains. While psychology seeks to understand human cognition, the field of Explainable AI (XAI) develops methods to interpret…

Human-Computer Interaction · Computer Science 2025-11-25 Roussel Rahman , Aashwin Ananda Mishra , Wan-Lin Hu

Explainable Artificial Intelligence (XAI) plays a crucial role in fostering transparency and trust in AI systems, where traditional XAI approaches typically offer one level of abstraction for explanations, often in the form of heatmaps…

While there has been a recent explosion of work on ExplainableAI ExAI on deep models that operate on imagery and tabular data, textual datasets present new challenges to the ExAI community. Such challenges can be attributed to the lack of…

Computation and Language · Computer Science 2022-10-14 Julia El Zini , Mariette Awad

Deep learning models achieved high accuracy in pneumonia detection from chest X-rays. However, their generalization across clinical domains remains limited due to variations in imaging devices, acquisition protocols, and institutional…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Danu Kim

Nowadays, deep neural networks are widely used in mission critical systems such as healthcare, self-driving vehicles, and military which have direct impact on human lives. However, the black-box nature of deep neural networks challenges its…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Arun Das , Paul Rad

The complex nature of disease mechanisms and the variability of patient symptoms pose significant challenges in developing effective diagnostic tools. Although machine learning (ML) has made substantial advances in medical diagnosis, the…

Pneumothorax, a life threatening disease, needs to be diagnosed immediately and efficiently. The prognosis in this case is not only time consuming but also prone to human errors. So an automatic way of accurate diagnosis using chest X-rays…

Computer Vision and Pattern Recognition · Computer Science 2020-12-23 Tahira Iqbal , Arslan Shaukat , Usman Akram , Zartasha Mustansar , Yung-Cheol Byun

In addition to the impressive predictive power of machine learning (ML) models, more recently, explanation methods have emerged that enable an interpretation of complex non-linear learning models such as deep neural networks. Gaining a…

Machine Learning · Computer Science 2023-01-18 Simon Letzgus , Patrick Wagner , Jonas Lederer , Wojciech Samek , Klaus-Robert Müller , Gregoire Montavon

Human understandable explanation of deep learning models is essential for various critical and sensitive applications. Unlike image or tabular data where the importance of each input feature (for the classifier's decision) can be directly…

Machine Learning · Computer Science 2025-04-07 Shahbaz Rezaei , Xin Liu

The success of recent Artificial Intelligence (AI) models has been accompanied by the opacity of their internal mechanisms, due notably to the use of deep neural networks. In order to understand these internal mechanisms and explain the…

Artificial Intelligence · Computer Science 2025-07-18 Léo Saulières
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