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Computer-aided diagnosis for medical imaging is a well-studied field that aims to provide real-time decision support systems for physicians. These systems attempt to detect and diagnose a plethora of medical conditions across a variety of…

Artificial Intelligence · Computer Science 2022-05-25 Glen Smith , Qiao Zhang , Christopher MacLellan

Although machine learning (ML) models of AI achieve high performances in medicine, they are not free of errors. Empowering clinicians to identify incorrect model recommendations is crucial for engendering trust in medical AI. Explainable AI…

Artificial Intelligence · Computer Science 2022-12-20 Isil Guzey , Ozlem Ucar , Nukhet Aladag Ciftdemir , Betul Acunas

Pneumothorax is a medical emergency caused by abnormal accumulation of air in the pleural space - the potential space between the lungs and chest wall. On 2D chest radiographs, pneumothorax occurs within the thoracic cavity and outside of…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Han Yuan , Chuan Hong , Nguyen Tuan Anh Tran , Xinxing Xu , Nan Liu

Limited expert time is a key bottleneck in medical imaging. Due to advances in image classification, AI can now serve as decision-support for medical experts, with the potential for great gains in radiologist productivity and, by extension,…

Machine Learning · Computer Science 2021-06-10 Tomas Folke , Scott Cheng-Hsin Yang , Sean Anderson , Patrick Shafto

Many visualizations have been developed for explainable AI (XAI), but they often require further reasoning by users to interpret. Investigating XAI for high-stakes medical diagnosis, we propose improving domain alignment with diagrammatic…

Artificial Intelligence · Computer Science 2025-02-27 Brian Y. Lim , Joseph P. Cahaly , Chester Y. F. Sng , Adam Chew

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira

Nowadays Artificial Intelligence (AI) has become a fundamental component of healthcare applications, both clinical and remote, but the best performing AI systems are often too complex to be self-explaining. Explainable AI (XAI) techniques…

Machine Learning · Computer Science 2022-09-15 Flavio Di Martino , Franca Delmastro

Deep learning models show significant potential for advancing AI-assisted medical diagnostics, particularly in detecting lung cancer through medical image modalities such as chest X-rays. However, the black-box nature of these models poses…

Machine Learning · Computer Science 2025-03-31 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

Last years have been characterized by an upsurge of opaque automatic decision support systems, such as Deep Neural Networks (DNNs). Although they have great generalization and prediction skills, their functioning does not allow obtaining…

As the field of healthcare increasingly adopts artificial intelligence, it becomes important to understand which types of explanations increase transparency and empower users to develop confidence and trust in the predictions made by…

Artificial Intelligence · Computer Science 2025-05-16 Felix Liedeker , Olivia Sanchez-Graillet , Moana Seidler , Christian Brandt , Jörg Wellmer , Philipp Cimiano

Deep Learning (DL) models processing images to recognize the health state of large infrastructure components can exhibit biases and rely on non-causal shortcuts. eXplainable Artificial Intelligence (XAI) can address these issues but…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Giovanni Floreale , Piero Baraldi , Enrico Zio , Olga Fink

Deep learning models have shown promise in lung pathology detection from chest X-rays, but widespread clinical adoption remains limited due to opaque model decision-making. In prior work, we introduced ClinicXAI, a human-centric,…

Artificial Intelligence · Computer Science 2026-04-17 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

A key issue in critical contexts such as medical diagnosis is the interpretability of the deep learning models adopted in decision-making systems. Research in eXplainable Artificial Intelligence (XAI) is trying to solve this issue. However,…

Computer Vision and Pattern Recognition · Computer Science 2021-11-24 Carlo Metta , Andrea Beretta , Riccardo Guidotti , Yuan Yin , Patrick Gallinari , Salvatore Rinzivillo , Fosca Giannotti

Accurate and interpretable image-based diagnosis remains a fundamental challenge in medical AI, particularly under domain shifts and rare-class conditions. Deep learning models often struggle with real-world distribution changes, exhibit…

Machine Learning · Computer Science 2025-12-13 Midhat Urooj , Ayan Banerjee , Farhat Shaikh , Kuntal Thakur , Sandeep Gupta

The increasing demand for transparent and reliable models, particularly in high-stakes decision-making areas such as medical image analysis, has led to the emergence of eXplainable Artificial Intelligence (XAI). Post-hoc XAI techniques,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Junlin Hou , Sicen Liu , Yequan Bie , Hongmei Wang , Andong Tan , Luyang Luo , Hao Chen

Explainable artificial intelligence (XAI) has become increasingly important in biomedical image analysis to promote transparency, trust, and clinical adoption of DL models. While several surveys have reviewed XAI techniques, they often lack…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Getamesay Haile Dagnaw , Yanming Zhu , Muhammad Hassan Maqsood , Wencheng Yang , Xingshuai Dong , Xuefei Yin , Alan Wee-Chung Liew

Recently, post hoc explanation methods have emerged to enhance model transparency by attributing model outputs to input features. However, these methods face challenges due to their specificity to certain neural network architectures and…

Machine Learning · Computer Science 2025-05-16 Seongun Kim , Sol A Kim , Geonhyeong Kim , Enver Menadjiev , Chanwoo Lee , Seongwook Chung , Nari Kim , Jaesik Choi

Ensuring both transparency and safety is critical when deploying Deep Neural Networks (DNNs) in high-risk applications, such as medicine. The field of explainable AI (XAI) has proposed various methods to comprehend the decision-making…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Maximilian Dreyer , Reduan Achtibat , Wojciech Samek , Sebastian Lapuschkin

Heatmaps are widely used to interpret deep neural networks, particularly for computer vision tasks, and the heatmap-based explainable AI (XAI) techniques are a well-researched topic. However, most studies concentrate on enhancing the…

Computer Vision and Pattern Recognition · Computer Science 2023-04-06 Osman Tursun , Simon Denman , Sridha Sridharan , Clinton Fookes

The Deep learning (DL) models for diagnosing breast cancer from mammographic images often operate as "black boxes", making it difficult for healthcare professionals to trust and understand their decision-making processes. The study presents…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Maryam Ahmed , Tooba Bibi , Rizwan Ahmed Khan , Sidra Nasir
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