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We propose a modified expectation-maximization algorithm by introducing the concept of quantum annealing, which we call the deterministic quantum annealing expectation-maximization (DQAEM) algorithm. The expectation-maximization (EM)…

Machine Learning · Statistics 2017-01-13 Hideyuki Miyahara , Koji Tsumura , Yuki Sughiyama

DNA sequence alignment is important today as it is usually the first step in finding gene mutation, evolutionary similarities, protein structure, drug development and cancer treatment. Covid-19 is one recent example. There are many…

Genomics · Quantitative Biology 2023-06-01 Suchindra , Preetam Nagaraj

Various methods have been developed to analyze the association between organisms and their genomic sequences. Among them, sequence alignment is the most frequently used for comparative analysis of biological genomes. However, the…

Quantitative Methods · Quantitative Biology 2020-10-27 Yong Joon Song , Dong Jin Ji , Hye In Seo , Gyu Bum Han , Dong Ho Cho

Quantum annealing solves combinatorial optimization problems by finding the energetic ground states of an embedded Hamiltonian. However, quantum annealing dynamics under the embedded Hamiltonian may violate the principles of adiabatic…

Quantum Physics · Physics 2021-04-08 Erica Grant , Travis Humble

Reference-guided DNA sequencing and alignment is an important process in computational molecular biology. The amount of DNA data grows very fast, and many new genomes are waiting to be sequenced while millions of private genomes need to be…

Feature selection is a machine learning technique for identifying relevant variables in classification and regression models. In single-cell RNA sequencing (scRNA-seq) data analysis, feature selection is used to identify relevant genes that…

Genomics · Quantitative Biology 2025-12-02 Selim Romero , Shreyan Gupta , Victoria Gatlin , Robert S. Chapkin , James J. Cai

Quantum algorithms are emerging tools in the design of functional materials due to their powerful solution space search capability. How to balance the high price of quantum computing resources and the growing computing needs has become an…

Quantum Physics · Physics 2024-05-13 Zhihao Xu , Wenjie Shang , Seongmin Kim , Alexandria Bobbitt , Eungkyu Lee , Tengfei Luo

Feature selection is a common step in many ranking, classification, or prediction tasks and serves many purposes. By removing redundant or noisy features, the accuracy of ranking or classification can be improved and the computational cost…

Information Retrieval · Computer Science 2022-05-10 Maurizio Ferrari Dacrema , Fabio Moroni , Riccardo Nembrini , Nicola Ferro , Guglielmo Faggioli , Paolo Cremonesi

Quantum annealing aims to exploit quantum mechanics to speed up the search for the solution to optimization problems. Most problems exhibit complete connectivity between the logical spin variables after they are mapped to the Ising spin…

Quantum Physics · Physics 2016-08-24 Tameem Albash , Walter Vinci , Daniel A. Lidar

Machine learning applications are limited by computational power. In this paper, we gain novel insights into the application of quantum annealing (QA) to machine learning (ML) through experiments in natural language processing (NLP),…

Quantum Physics · Physics 2016-03-28 Joseph Dulny , Michael Kim

The Kemeny Rank Aggregation (KRA) problem is a well-studied problem in the field of Social Choice with a variety of applications in many different areas like databases and search engines. Intuitively, given a set of votes over a set of…

Quantum Physics · Physics 2023-01-13 Sven Fiergolla , Kevin Goergen , Patrick Neises , Petra Wolf

The study of optimal control of quantum annealing by modulating the pace of evolution and by introducing a counterdiabatic potential has gained significant attention in recent times. In this work, we present a numerical approach based on…

With the advent of quantum computers, researchers are exploring if quantum mechanics can be leveraged to solve important problems in ways that may provide advantages not possible with conventional or classical methods. A previous work by…

Quantum Physics · Physics 2018-11-02 Ajinkya Borle , Samuel J. Lomonaco

Benchmarking Quantum Process Units (QPU) at an application level usually requires considering the whole programming stack of the quantum computer. One critical task is the minor-embedding (resp. transpilation) step, which involves…

Quantum Physics · Physics 2024-08-02 Valentin Gilbert , Julien Rodriguez , Stéphane Louise

Multiple rotation averaging (MRA) is a fundamental optimization problem in 3D vision and robotics that aims to recover globally consistent absolute rotations from noisy relative measurements. Established classical methods, such as L1-IRLS…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Shuteng Wang , Natacha Kuete Meli , Michael Möller , Vladislav Golyanik

The field of Quantum Computing has gathered significant popularity in recent years and a large number of papers have studied its effectiveness in tackling many tasks. We focus in particular on Quantum Annealing (QA), a meta-heuristic solver…

Quantum Physics · Physics 2026-03-03 Riccardo Pellini , Maurizio Ferrari Dacrema

We propose an approach for multiple sequence alignment (MSA) derived from the dynamic time warping viewpoint and recent techniques of curve synchronization developed in the context of functional data analysis. Starting from pairwise…

Applications · Statistics 2017-01-09 Ana Arribas-Gil , Catherine Matias

Optimisation plays a central role in a wide range of scientific and industrial applications, and quantum computing has been widely proposed as a means to achieve computational advantages in this domain. To date, research into the design of…

Quantum Physics · Physics 2026-02-03 Stuart Ferguson , Petros Wallden

We assess the prospects for algorithms within the general framework of quantum annealing (QA) to achieve a quantum speedup relative to classical state of the art methods in combinatorial optimization and related sampling tasks. We argue for…

Quantum Physics · Physics 2021-06-22 E. J. Crosson , D. A. Lidar

This paper summarizes a quantum algorithm of [R.D. Somma, et.al., Phys. Rev. Lett. 101, 130504 (2008)] that simulates a classical annealing process for solving discrete optimization problems. The complexity of the quantum algorithm scales…

Quantum Physics · Physics 2015-12-16 Sergio Boixo , Rolando D. Somma
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