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This paper presents the first approach to visualize the importance of topological features that define classes of data. Topological features, with their ability to abstract the fundamental structure of complex data, are an integral…

Machine Learning · Computer Science 2023-09-26 Yu Qin , Brittany Terese Fasy , Carola Wenk , Brian Summa

In this research, we propose a deep learning based approach for speeding up the topology optimization methods. The problem we seek to solve is the layout problem. The main novelty of this work is to state the problem as an image…

Machine Learning · Computer Science 2017-09-28 Ivan Sosnovik , Ivan Oseledets

Although the preservation of shape continuity and physiological anatomy is a natural assumption in the segmentation of medical images, it is often neglected by deep learning methods that mostly aim for the statistical modeling of input data…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 Yousef Yeganeh , Azade Farshad , Goktug Guevercin , Amr Abu-zer , Rui Xiao , Yongjian Tang , Ehsan Adeli , Nassir Navab

Deep generative models have emerged as a powerful tool for learning useful molecular representations and designing novel molecules with desired properties, with applications in drug discovery and material design. However, most existing deep…

Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Rushi Jiao , Yichi Zhang , Le Ding , Rong Cai , Jicong Zhang

Spatial graphs provide a lightweight and elegant representation of curvilinear anatomical structures such as blood vessels, lung airways, and neuronal networks. Accurately modeling these graphs is crucial in clinical and (bio-)medical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Chinmay Prabhakar , Bastian Wittmann , Tamaz Amiranashvili , Paul Büschl , Ezequiel de la Rosa , Julian McGinnis , Benedikt Wiestler , Bjoern Menze , Suprosanna Shit

Automatic segmentation of neuronal topology is critical for handling large scale neuroimaging data, as it can greatly accelerate neuron annotation and analysis. However, the intricate morphology of neuronal branches and the occlusions among…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Huayu Fu , Jiamin Li , Haozhi Qu , Xiaolin Hu , Zengcai Guo

This paper demonstrates a self-supervised framework for learning voxel-wise coarse-to-fine representations tailored for dense downstream tasks. Our approach stems from the observation that existing methods for hierarchical representation…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Eytan Kats , Jochen G. Hirsch , Mattias P. Heinrich

Most efforts in interpretability in deep learning have focused on (1) extracting explanations of a specific downstream task in relation to the input features and (2) imposing constraints on the model, often at the expense of predictive…

Machine Learning · Computer Science 2022-02-22 Marco Bertolini , Djork-Arné Clevert , Floriane Montanari

Morphological methods play a crucial role in remote sensing image processing, due to their ability to capture and preserve small structural details. However, most of the existing deep learning models for semantic segmentation are based on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Jun Xie , Wenxiao Li , Faqiang Wang , Liqiang Zhang , Zhengyang Hou , Jun Liu

The topological analysis of four-dimensional (4D) image-type data is challenged by the immense size that these datasets can reach. This can render the direct application of methods, like persistent homology and convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Khalil Mathieu Hannouch , Stephan Chalup

Successful training of convolutional neural networks is often associated with sufficiently deep architectures composed of high amounts of features. These networks typically rely on a variety of regularization and pruning techniques to…

Computer Vision and Pattern Recognition · Computer Science 2017-10-23 Martin Mundt , Tobias Weis , Kishore Konda , Visvanathan Ramesh

Explainability of deep neural networks is one of the most challenging and interesting problems in the field. In this study, we investigate the topic focusing on the interpretability of deep learning-based registration methods. In…

For brain tumour segmentation, deep learning models can achieve human expert-level performance given a large amount of data and pixel-level annotations. However, the expensive exercise of obtaining pixel-level annotations for large amounts…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Xiao Liu , Antanas Kascenas , Hannah Watson , Sotirios A. Tsaftaris , Alison Q. O'Neil

Comprehensive surgical planning require complex patient-specific anatomical models. For instance, functional muskuloskeletal simulations necessitate all relevant structures to be segmented, which could be performed in real-time using deep…

Image and Video Processing · Electrical Eng. & Systems 2019-05-20 Firat Ozdemir , Orcun Goksel

The rapid progress of Artificial Intelligence research came with the development of increasingly complex deep learning models, leading to growing challenges in terms of computational complexity, energy efficiency and interpretability. In…

Machine Learning · Computer Science 2023-06-28 Yuanrong Wang , Antonio Briola , Tomaso Aste

Deep learning models for medical data are typically trained using task specific objectives that encourage representations to collapse onto a small number of discriminative directions. While effective for individual prediction problems, this…

Machine Learning · Computer Science 2026-02-10 Yuanyun Zhang , Mingxuan Zhang , Siyuan Li , Zihan Wang , Haoran Chen , Wenbo Zhou , Shi Li

Despite the recent success of deep learning methods at achieving new state-of-the-art accuracy for medical image segmentation, some major limitations are still restricting their deployment into clinics. One major limitation of deep…

Image and Video Processing · Electrical Eng. & Systems 2023-05-30 Lucas Fidon

Topology applied to real world data using persistent homology has started to find applications within machine learning, including deep learning. We present a differentiable topology layer that computes persistent homology based on level set…

Despite significant advances in the field of deep learning in applications to various fields, explaining the inner processes of deep learning models remains an important and open question. The purpose of this article is to describe and…

Machine Learning · Computer Science 2022-04-20 German Magai , Anton Ayzenberg
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