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Neuroscientific data analysis has classically involved methods for statistical signal and image processing, drawing on linear algebra and stochastic process theory. However, digitized neuroanatomical data sets containing labelled neurons,…

Computational Geometry · Computer Science 2018-05-15 Suyi Wang , Xu Li , Partha Mitra , Yusu Wang

Segmentation algorithms are prone to make topological errors on fine-scale structures, e.g., broken connections. We propose a novel method that learns to segment with correct topology. In particular, we design a continuous-valued loss…

Computer Vision and Pattern Recognition · Computer Science 2019-06-18 Xiaoling Hu , Li Fuxin , Dimitris Samaras , Chao Chen

Semantic segmentation is a crucial task in biomedical image processing, which recent breakthroughs in deep learning have allowed to improve. However, deep learning methods in general are not yet widely used in practice since they require…

Computer Vision and Pattern Recognition · Computer Science 2019-07-12 Melanie Lubrano di Scandalea , Christian S. Perone , Mathieu Boudreau , Julien Cohen-Adad

Deformable objects present a formidable challenge for robotic manipulation due to the lack of canonical low-dimensional representations and the difficulty of capturing, predicting, and controlling such objects. We construct compact…

Robotics · Computer Science 2021-05-12 Rika Antonova , Anastasiia Varava , Peiyang Shi , J. Frederico Carvalho , Danica Kragic

Image annotation aims to annotate a given image with a variable number of class labels corresponding to diverse visual concepts. In this paper, we address two main issues in large-scale image annotation: 1) how to learn a rich feature…

Computer Vision and Pattern Recognition · Computer Science 2018-10-22 Yulei Niu , Zhiwu Lu , Ji-Rong Wen , Tao Xiang , Shih-Fu Chang

Despite tremendous progress over the past decade, deep learning methods generally fall short of human-level systematic generalization. It has been argued that explicitly capturing the underlying structure of data should allow connectionist…

Machine Learning · Computer Science 2023-04-26 Andrea Dittadi

Advances in deep learning models have revolutionized the study of biomolecule systems and their mechanisms. Graph representation learning, in particular, is important for accurately capturing the geometric information of biomolecules at…

Quantitative Methods · Quantitative Biology 2023-04-07 Xinye Xiong , Bingxin Zhou , Yu Guang Wang

Representations in the auditory cortex might be based on mechanisms similar to the visual ventral stream; modules for building invariance to transformations and multiple layers for compositionality and selectivity. In this paper we propose…

We perform topological data analysis on the internal states of convolutional deep neural networks to develop an understanding of the computations that they perform. We apply this understanding to modify the computations so as to (a) speed…

Machine Learning · Computer Science 2018-11-06 Gunnar Carlsson , Rickard Brüel Gabrielsson

Social network analysis is an important problem in data mining. A fundamental step for analyzing social networks is to encode network data into low-dimensional representations, i.e., network embeddings, so that the network topology…

Social and Information Networks · Computer Science 2019-04-19 Qiaoyu Tan , Ninghao Liu , Xia Hu

Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…

Machine Learning · Computer Science 2025-02-07 Michelle M. Li , Kexin Huang , Marinka Zitnik

While conventional computer vision emphasizes pixel-level and feature-based objectives, medical image analysis of intricate biological structures necessitates explicit representation of their complex topological properties. Despite their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Yousef Yeganeh , Rui Xiao , Goktug Guvercin , Nassir Navab , Azade Farshad

Deep learning has become the dominant approach for creating high capacity, scalable models across diverse data modalities. However, because these models rely on a large number of learned parameters, tightly couple feature extraction with…

Artificial Intelligence · Computer Science 2026-05-12 Adam Gould , Francesca Toni

Topological data analysis combines machine learning with methods from algebraic topology. Persistent homology, a method to characterize topological features occurring in data at multiple scales is of particular interest. A major obstacle to…

Algebraic Topology · Mathematics 2019-04-25 Nello Blaser , Morten Brun

In medical imaging, most of the image registration methods implicitly assume a one-to-one correspondence between the source and target images (i.e., diffeomorphism). However, this is not necessarily the case when dealing with pathological…

Image and Video Processing · Electrical Eng. & Systems 2022-02-03 Matthis Maillard , Anton François , Joan Glaunès , Isabelle Bloch , Pietro Gori

Unsupervised feature learning often finds low-dimensional embeddings that capture the structure of complex data. For tasks for which prior expert topological knowledge is available, incorporating this into the learned representation may…

Machine Learning · Computer Science 2022-03-08 Robin Vandaele , Bo Kang , Jefrey Lijffijt , Tijl De Bie , Yvan Saeys

Deep learning methods have demonstrated outstanding performances on classification and regression tasks on homogeneous data types (e.g., image, audio, and text data). However, tabular data still pose a challenge, with classic machine…

Machine Learning · Computer Science 2023-11-15 Antonio Briola , Yuanrong Wang , Silvia Bartolucci , Tomaso Aste

Skeletonization extracts thin representations from images that compactly encode their geometry and topology. These representations have become an important topological prior for preserving connectivity in curvilinear structures, aiding…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Luis D. Reyes Vargas , Martin J. Menten , Johannes C. Paetzold , Nassir Navab , Mohammad Farid Azampour

Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks. However, due to large variations in biomedical…

Computer Vision and Pattern Recognition · Computer Science 2017-06-16 Lin Yang , Yizhe Zhang , Jianxu Chen , Siyuan Zhang , Danny Z. Chen

Computational topology provides a tool, persistent homology, to extract quantitative descriptors from structured objects (images, graphs, point clouds, etc). These descriptors can then be involved in optimization problems, typically as a…

Computational Geometry · Computer Science 2026-03-27 Mathieu Carriere , Yuichi Ike , Théo Lacombe , Naoki Nishikawa