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Related papers: A Unified Model for Longitudinal Multi-Modal Multi…

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Traditional multimodal learners find unified representations for tasks like visual question answering, but rely heavily on paired datasets. However, an overlooked yet potentially powerful question is: can one leverage auxiliary unpaired…

Machine Learning · Computer Science 2025-10-10 Sharut Gupta , Shobhita Sundaram , Chenyu Wang , Stefanie Jegelka , Phillip Isola

Multimodal learning has achieved great successes in many scenarios. Compared with unimodal learning, it can effectively combine the information from different modalities to improve the performance of learning tasks. In reality, the…

Machine Learning · Computer Science 2021-08-25 Fei Ma , Xiangxiang Xu , Shao-Lun Huang , Lin Zhang

Multiple Sclerosis (MS) is a chronic disease characterized by progressive or alternate impairment of neurological functions (motor, sensory, visual, and cognitive). Predicting disease progression with a probabilistic and time-dependent…

Multimodal learning with incomplete input data (missing modality) is practical and challenging. In this work, we conduct an in-depth analysis of this challenge and find that modality dominance has a significant negative impact on the model…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Hao Wang , Shengda Luo , Guosheng Hu , Jianguo Zhang

Data collected in clinical trials are often composed of multiple types of variables. For example, laboratory measurements and vital signs are longitudinal data of continuous or categorical variables, adverse events may be recurrent events,…

Methodology · Statistics 2023-01-12 Tuo Wang , Rachel Zilinskas , Ying Li , Yongming Qu

Due to potential applications in chronic disease management and personalized healthcare, the EHRs data analysis has attracted much attention of both researchers and practitioners. There are three main challenges in modeling longitudinal and…

Machine Learning · Computer Science 2019-12-03 Yi Huang , Xiaoshan Yang , Changsheng Xu

Knee osteoarthritis (OA) is a common degenerate joint disorder that affects a large population of elderly people worldwide. Accurate radiographic assessment of knee OA severity plays a critical role in chronic patient management. Current…

Image and Video Processing · Electrical Eng. & Systems 2021-12-20 Kang Zheng , Yirui Wang , Chen-I Hsieh , Le Lu , Jing Xiao , Chang-Fu Kuo , Shun Miao

Multimodal learning often outperforms its unimodal counterparts by exploiting unimodal contributions and cross-modal interactions. However, focusing only on integrating multimodal features into a unified comprehensive representation…

Machine Learning · Computer Science 2025-05-15 Sehwan Moon , Hyunju Lee

Irregular multivariate time series with missing values present significant challenges for predictive modeling in domains such as healthcare. While deep learning approaches often focus on temporal interpolation or complex architectures to…

Machine Learning · Computer Science 2026-03-16 Dingyi Nie , Yixing Wu , C. -C. Jay Kuo

We are interested in survival analysis of hemodialysis patients for whom several biomarkers are recorded over time. Motivated by this challenging problem, we propose a general framework for multivariate joint longitudinal-survival modeling…

Healthcare professionals have long envisioned using the enormous processing powers of computers to discover new facts and medical knowledge locked inside electronic health records. These vast medical archives contain time-resolved…

Machine Learning · Computer Science 2020-05-15 Ahmed Allam , Matthias Dittberner , Anna Sintsova , Dominique Brodbeck , Michael Krauthammer

Segmentation of Multiple Sclerosis (MS) lesions in longitudinal brain MR scans is performed for monitoring the progression of MS lesions. We hypothesize that the spatio-temporal cues in longitudinal data can aid the segmentation algorithm.…

Image and Video Processing · Electrical Eng. & Systems 2020-09-29 Stefan Denner , Ashkan Khakzar , Moiz Sajid , Mahdi Saleh , Ziga Spiclin , Seong Tae Kim , Nassir Navab

We propose to learn latent graphical models when data have mixed variables and missing values. This model could be used for further data analysis, including regression, classification, ranking etc. It also could be used for imputing missing…

Methodology · Statistics 2015-11-17 Xiao Li , Jinzhu Jia , Yuan Yao

Biomedical research has revealed the crucial role of miRNAs in the progression of many diseases, and computational prediction methods are increasingly proposed for assisting biological experiments to verify miRNA-disease associations…

Computational Engineering, Finance, and Science · Computer Science 2023-08-29 Yi Zhou , Meixuan Wu , Chengzhou Ouyang , Min Zhu

Multimodal information retrieval (MIR) faces inherent challenges due to the heterogeneity of data sources and the complexity of cross-modal alignment. While previous studies have identified modal gaps in feature spaces, a systematic…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Fanheng Kong , Jingyuan Zhang , Yahui Liu , Hongzhi Zhang , Shi Feng , Xiaocui Yang , Daling Wang , Yu Tian , Victoria W. , Fuzheng Zhang , Guorui Zhou

Healthcare relies on multiple types of data, such as medical images, genetic information, and clinical records, to improve diagnosis and treatment. However, missing data is a common challenge due to privacy restrictions, cost, and technical…

Machine Learning · Computer Science 2025-03-13 Nazanin Moradinasab , Saurav Sengupta , Jiebei Liu , Sana Syed , Donald E. Brown

In recent years, single modality based gait recognition has been extensively explored in the analysis of medical images or other sensory data, and it is recognised that each of the established approaches has different strengths and…

Computer Vision and Pattern Recognition · Computer Science 2021-01-08 Aite Zhao , Jianbo Li , Junyu Dong , Lin Qi , Qianni Zhang , Ning Li , Xin Wang , Huiyu Zhou

Machine learning holds promise for advancing clinical decision support, yet it remains unclear when multimodal learning truly helps in practice, particularly under modality missingness and fairness constraints. In this work, we conduct a…

Machine Learning · Computer Science 2026-03-02 Kejing Yin , Haizhou Xu , Wenfang Yao , Chen Liu , Zijie Chen , Yui Haang Cheung , William K. Cheung , Jing Qin

To study neurodegenerative diseases, longitudinal studies are carried on volunteer patients. During a time span of several months to several years, they go through regular medical visits to acquire data from different modalities, such as…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Cecilia Ostertag , Marie Beurton-Aimar , Muriel Visani , Thierry Urruty , Karell Bertet

Longitudinal data are often plagued with sparsity of time points where measurements are available. The functional data analysis perspective has been shown to provide an effective and flexible approach to address this problem for the case…

Methodology · Statistics 2017-02-13 Matthew Dawson , Hans-Georg Müller
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