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A pressing challenge in medical research is to identify optimal treatments for individual patients. This is particularly challenging in mental health settings where mean responses are often similar across multiple treatments. For example,…

Methodology · Statistics 2022-03-08 Lanqiu Yao , Thaddeus Tarpey

Existing multimodal tasks mostly target at the complete input modality setting, i.e., each modality is either complete or completely missing in both training and test sets. However, the randomly missing situations have still been…

Computation and Language · Computer Science 2022-10-25 Wei Han , Hui Chen , Min-Yen Kan , Soujanya Poria

Trajectory prediction is a crucial undertaking in understanding entity movement or human behavior from observed sequences. However, current methods often assume that the observed sequences are complete while ignoring the potential for…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Yi Xu , Armin Bazarjani , Hyung-gun Chi , Chiho Choi , Yun Fu

We propose a semi-partitioned Generalized Method of Moments (GMM) framework for analyzing longitudinal data with time-dependent covariates, within a marginal modeling paradigm. This approach addresses limitations of both aggregated and…

Methodology · Statistics 2026-03-04 Niloofar Ramezani , Jeffrey R. Wilson

While the ICD code assignment problem has been widely studied, most works have focused on post-discharge document classification. Models for early forecasting of this information could be used for identifying health risks, suggesting…

Machine Learning · Computer Science 2025-08-18 Cindy Shih-Ting Huang , Clarence Boon Liang Ng , Marek Rei

Knee osteoarthritis (OA) is a widespread chronic condition that impairs mobility and diminishes quality of life. Despite the proven benefits of exercise therapy and patient education in managing the OA symptoms pain and functional…

Machine Learning · Computer Science 2024-10-17 M. Rafiei , S. Das , M. Bakhtiari , E. M. Roos , S. T. Skou , D. T. Grønne , J. Baumbach , L. Baumbach

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

Machine Learning · Computer Science 2025-02-26 Sifal Klioui , Sana Sellami , Youssef Trardi

Modular object-centric representations are essential for *human-like reasoning* but are challenging to obtain under spatial ambiguities, *e.g. due to occlusions and view ambiguities*. However, addressing challenges presents both theoretical…

Machine Learning · Computer Science 2025-06-10 Avinash Kori , Francesca Toni , Ben Glocker

Standard multi-modal models assume the use of the same modalities in training and inference stages. However, in practice, the environment in which multi-modal models operate may not satisfy such assumption. As such, their performances…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Sangmin Woo , Sumin Lee , Yeonju Park , Muhammad Adi Nugroho , Changick Kim

As a crucial extension of entity alignment (EA), multi-modal entity alignment (MMEA) aims to identify identical entities across disparate knowledge graphs (KGs) by exploiting associated visual information. However, existing MMEA approaches…

Artificial Intelligence · Computer Science 2023-08-02 Zhuo Chen , Lingbing Guo , Yin Fang , Yichi Zhang , Jiaoyan Chen , Jeff Z. Pan , Yangning Li , Huajun Chen , Wen Zhang

Data from multi-modality provide complementary information in clinical prediction, but missing data in clinical cohorts limits the number of subjects in multi-modal learning context. Multi-modal missing imputation is challenging with…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Riqiang Gao , Yucheng Tang , Kaiwen Xu , Ho Hin Lee , Steve Deppen , Kim Sandler , Pierre Massion , Thomas A. Lasko , Yuankai Huo , Bennett A. Landman

In medical vision, different imaging modalities provide complementary information. However, in practice, not all modalities may be available during inference or even training. Previous approaches, e.g., knowledge distillation or image…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Aishik Konwer , Xiaoling Hu , Joseph Bae , Xuan Xu , Chao Chen , Prateek Prasanna

The majority of biomedical studies use limited datasets that may not generalize over large heterogeneous datasets that have been collected over several decades. The current paper develops and validates several multimodal models that can…

Predicting whether subjects with mild cognitive impairment (MCI) will convert to Alzheimer's disease is a significant clinical challenge. Longitudinal variations and complementary information inherent in longitudinal and multimodal data are…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Tao Wang , Xiumei Chen , Xiaoling Zhang , Shuoling Zhou , Qianjin Feng , Meiyan Huang

Robust forecasting of the future anatomical changes inflicted by an ongoing disease is an extremely challenging task that is out of grasp even for experienced healthcare professionals. Such a capability, however, is of great importance…

Computer Vision and Pattern Recognition · Computer Science 2022-11-09 Dmitrii Lachinov , Arunava Chakravarty , Christoph Grechenig , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

The rapid development of diagnostic technologies in healthcare is leading to higher requirements for physicians to handle and integrate the heterogeneous, yet complementary data that are produced during routine practice. For instance, the…

Machine Learning · Computer Science 2023-01-30 Can Cui , Haichun Yang , Yaohong Wang , Shilin Zhao , Zuhayr Asad , Lori A. Coburn , Keith T. Wilson , Bennett A. Landman , Yuankai Huo

Longitudinal medical images are essential for monitoring disease progression by capturing spatiotemporal changes associated with dynamic biological processes. While current methods have made progress in modeling spatiotemporal patterns,…

Quantitative Methods · Quantitative Biology 2025-09-15 Shuaitong Zhang , Yuchen Sun , Yong Ao , Xuehuan Zhang , Ruoshui Yang , Jiantao Xu , Zuwu Ai , Haike Zhang , Xiang Yang , Yao Xu , Kunwei Li , Duanduan Chen

Assessing lesions and tracking their progression over time in brain magnetic resonance (MR) images is essential for diagnosing and monitoring multiple sclerosis (MS). Machine learning models have shown promise in automating the segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Berke Doga Basaran , Paul M. Matthews , Wenjia Bai

Biomedical data is inherently multimodal, consisting of electronic health records, medical imaging, digital pathology, genome sequencing, wearable sensors, and more. The application of artificial intelligence tools to these multifaceted…

Machine Learning · Computer Science 2024-08-26 Shentong Mo , Paul Pu Liang

Joint models of longitudinal and event-time data have been extensively studied and applied in many different fields. Estimation of joint models is challenging, most present procedures are computational expensive and have a strict…

Methodology · Statistics 2018-09-05 Yanqiao Zheng , Xiaobing Zhao , Xiaoqi Zhang
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