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Cone beam computed tomography (CBCT) is an emerging medical imaging technique to visualize the internal anatomical structures of patients. During a CBCT scan, several projection images of different angles or views are collectively utilized…

Image and Video Processing · Electrical Eng. & Systems 2024-01-18 Heejun Shin , Taehee Kim , Jongho Lee , Se Young Chun , Seungryung Cho , Dongmyung Shin

The clinical application of cone-beam computed tomography (CBCT) is constrained by the inherent trade-off between radiation exposure and image quality. Ultra-sparse angular sampling, employed to reduce dose, introduces severe undersampling…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Junlin Wang , Jiancheng Fang , Peng Peng , Shaoyu Wang , Qiegen Liu

Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…

Treatment planning systems at proton-therapy centres generally use X-ray computed tomography (CT) as primary imaging technique to infer the proton treatment doses to tumour and healthy tissues. However, proton stopping powers in the body,…

Single-Photon Emission Computed Tomography (SPECT) is widely applied for the diagnosis of coronary artery diseases. Low-dose (LD) SPECT aims to minimize radiation exposure but leads to increased image noise. Limited-view (LV) SPECT, such as…

Image and Video Processing · Electrical Eng. & Systems 2024-01-25 Xiongchao Chen , Bo Zhou , Xueqi Guo , Huidong Xie , Qiong Liu , James S. Duncan , Albert J. Sinusas , Chi Liu

Purpose: Cone-beam CT (CBCT) projection images provide anatomical data in real-time over several respiratory cycles, forming a comprehensive picture of tumor movement. We developed and validated a method which uses these projections to…

Medical Physics · Physics 2015-01-15 Bernard L. Jones , David Westerly , Moyed Miften

Cone beam computed tomography (CBCT) is an important imaging technology widely used in medical scenarios, such as diagnosis and preoperative planning. Using fewer projection views to reconstruct CT, also known as sparse-view reconstruction,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-07 Yiqun Lin , Jiewen Yang , Hualiang Wang , Xinpeng Ding , Wei Zhao , Xiaomeng Li

Flat-panel cone-beam CT (CBCT) has been applied clinically in a number of high-resolution applications. Increasing geometric magnification can potentially improve resolution, but also increases blur due to an extended x-ray focal-spot. We…

Medical Physics · Physics 2016-10-18 Steven Tilley , Wojciech Zbijewski , Jeffrey H. Siewerdsen , J. Webster Stayman

Sparse-view sampling in dual-energy computed tomography (DECT) significantly reduces radiation dose and increases imaging speed, yet is highly prone to artifacts. Although diffusion models have demonstrated potential in effectively handling…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Zini Chen , Yao Xiao , Junyan Zhang , Shaoyu Wang , Liu Shi , Qiegen Liu

Accurate dose calculations in proton therapy rely on high-quality CT images. While planning CTs (pCTs) serve as a reference for dosimetric planning, Cone Beam CT (CBCT) is used throughout Adaptive Radiotherapy (ART) to generate sCTs for…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 David Vallmanya Poch , Yorick Estievenart , Elnura Zhalieva , Sukanya Patra , Mohammad Yaqub , Souhaib Ben Taieb

Purpose: Organ-at-risk (OAR) delineation is a key step for cone-beam CT (CBCT) based adaptive radiotherapy planning that can be a time-consuming, labor-intensive, and subject-to-variability process. We aim to develop a fully automated…

CT images have been used to generate radiation therapy treatment plans for more than two decades. Dual-energy CT (DECT) has shown high accuracy in estimating electronic density or proton stopping-power maps used in treatment planning.…

Image and Video Processing · Electrical Eng. & Systems 2022-02-02 Tao Ge , Maria Medrano , Rui Liao , Jeffrey F. Williamson , David G. Politte , Bruce R. Whiting , Joseph A. O'Sullivan

Purpose/Objectives: To develop and assess a strategy of using deep learning (DL) to generate virtual monochromatic CT (VMCT) images from a single-energy CT (SECT) scan. Materials/Methods: The proposed data-driven VMCT imaging consists of…

Medical Physics · Physics 2020-05-21 Wei Zhao , Tianling Lyu , Yang Chen , Lei Xing

Ultra-low-dose positron emission tomography (PET) reconstruction holds significant potential for reducing patient radiation exposure and shortening examination times. However, it may also lead to increased noise and reduced imaging detail,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Mengxiao Geng , Ran Hong , Bingxuan Li , Qiegen Liu

Objective: This study aims at investigating a novel super resolution CBCT imaging technique with the dual-layer flat panel detector (DL-FPD). Approach: In DL-FPD based CBCT imaging, the low-energy and high-energy projections acquired from…

Medical Physics · Physics 2023-06-29 Jiongtao Zhu , Ting Su , Xin Zhang , Han Cui , Yuhang Tan , Hairong Zheng , Dong Liang , Jinchuan Guo , Yongshuai Ge

Computed tomography (CT) to cone-beam computed tomography (CBCT) deformable image registration (DIR) is a crucial step in adaptive radiation therapy. Current intensity-based registration algorithms, such as demons, may fail in the context…

Medical Physics · Physics 2017-08-23 Xin Zhen , Xuejun Gu , Hao Yan , Linghong Zhou , Xun Jia , Steve B. Jiang

Cone-beam computed tomography (CBCT) is an important tool facilitating computer aided interventions, despite often suffering from artifacts that pose challenges for accurate interpretation. While the degraded image quality can affect…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Maximilian E. Tschuchnig , Philipp Steininger , Michael Gadermayr

Early recurrence (ER) prediction after curative-intent resection remains a critical challenge in the clinical management of hepatocellular carcinoma (HCC). Although contrast-enhanced computed tomography (CT) with full multi-phase…

Quantitative Methods · Quantitative Biology 2025-10-10 Hsin-Pei Yu , Si-Qin Lyu , Yi-Hsien Hsieh , Weichung Wang , Tung-Hung Su , Jia-Horng Kao , Che Lin

Background: Cone-beam computed tomography (CBCT) plays a crucial role in image-guided radiotherapy, but artifacts and noise make them unsuitable for accurate dose calculation. Artificial intelligence methods have shown promise in enhancing…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Shi Yin , Hongqi Tan , Li Ming Chong , Haofeng Liu , Hui Liu , Kang Hao Lee , Jeffrey Kit Loong Tuan , Dean Ho , Yueming Jin

Computational tomography (CT) provides high-resolution medical imaging, but it can expose patients to high radiation. X-ray scanners have low radiation exposure, but their resolutions are low. This paper proposes a new conditional diffusion…

Image and Video Processing · Electrical Eng. & Systems 2025-01-20 Yun Su Jeong , Hye Bin Yoo , Il Yong Chun