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The advent of large-scale neural recordings has enabled new methods to discover the computational mechanisms of neural circuits by understanding the rules that govern how their state evolves over time. While these \textit{neural dynamics}…

Neurons and Cognition · Quantitative Biology 2023-09-13 Christopher Versteeg , Andrew R. Sedler , Jonathan D. McCart , Chethan Pandarinath

This study investigates the effectiveness of unsupervised outlier detection methods in audit analytics, utilizing USA spending data from the U.S. Department of Health and Human Services (DHHS) as a case example. We employ and compare…

Machine Learning · Computer Science 2025-09-25 Buhe Li , Berkay Kaplan , Maksym Lazirko , Aleksandr Kogan

Widespread stigma, both in the offline and online spaces, acts as a barrier to harm reduction efforts in the context of opioid use disorder (OUD). This stigma is prominently directed towards clinically approved medications for addiction…

Social and Information Networks · Computer Science 2025-04-16 Shravika Mittal , Darshi Shah , Shin Won Do , Mai ElSherief , Tanushree Mitra , Munmun De Choudhury

Substance use disorders (SUDs) are a growing concern globally, necessitating enhanced understanding of the problem and its trends through data-driven research. Social media are unique and important sources of information about SUDs,…

Computation and Language · Computer Science 2024-05-13 Yao Ge , Sudeshna Das , Karen O'Connor , Mohammed Ali Al-Garadi , Graciela Gonzalez-Hernandez , Abeed Sarker

With advanced data analytical techniques, efforts for more accurate decision support systems for disease prediction are on rise. Surveys by World Health Organization (WHO) indicate a great increase in number of diabetic patients and related…

Machine Learning · Computer Science 2017-06-27 Maham Jahangir , Hammad Afzal , Mehreen Ahmed , Khawar Khurshid , Raheel Nawaz

Progress in the biomedical field through the use of deep learning is hindered by the lack of interpretability of the models. In this paper, we study the RETAIN architecture for the forecasting of future glucose values for diabetic people.…

Machine Learning · Computer Science 2020-09-11 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

Recently, diabetic retinopathy (DR) screening utilizing ultra-wide optical coherence tomography angiography (UW-OCTA) has been used in clinical practices to detect signs of early DR. However, developing a deep learning-based DR analysis…

Image and Video Processing · Electrical Eng. & Systems 2022-10-19 Gitaek Kwon , Eunjin Kim , Sunho Kim , Seongwon Bak , Minsung Kim , Jaeyoung Kim

Background: Electronic health records (EHRs) are a data source for opioid research. Opioid use disorder is known to be under-coded as a diagnosis, yet problematic opioid use can be documented in clinical notes. Objectives: Our goals were 1)…

Diabetes mellitus is a major global health challenge, affecting over half a billion adults worldwide with prevalence projected to rise. Although the American Diabetes Association (ADA) provides clear diagnostic thresholds, early recognition…

Computation and Language · Computer Science 2025-09-29 Gaurav Kumar Gupta , Nirajan Acharya , Pranal Pande

Retinal imaging has emerged as a powerful, non-invasive modality for detecting and quantifying biomarkers of systemic diseases-ranging from diabetes and hypertension to Alzheimer's disease and cardiovascular disorders but current insights…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Tariq M Khan , Toufique Ahmed Soomro , Imran Razzak

Worldwide, in 2014, more than 1.9 billion adults, 18 years and older, were overweight. Of these, over 600 million were obese. Accurately documenting dietary caloric intake is crucial to manage weight loss, but also presents challenges…

Computer Vision and Pattern Recognition · Computer Science 2016-06-21 Chang Liu , Yu Cao , Yan Luo , Guanling Chen , Vinod Vokkarane , Yunsheng Ma

Diabetes mellitus affects over 537 million adults worldwide and remains a major challenge in preventive healthcare. Existing machine-learning studies primarily formulate diabetes prediction as a binary classification problem, while…

Machine Learning · Computer Science 2026-05-14 Vishal Pandey , Ruzina Haque Laskar , Rishav Tewari

The increased worldwide prevalence of obesity has sparked the interest of the scientific community towards tools that objectively and automatically monitor eating behavior. Despite the study of obesity being in the spotlight, such tools can…

Signal Processing · Electrical Eng. & Systems 2020-10-15 Konstantinos Kyritsis , Christos Diou , Anastasios Delopoulos

Opiates are some of the most effective pain relief medications available for patients suffering from cancer and surgery-related pain. Despite the affordability and effectiveness of these medications, access to opiates is highly…

Applications · Statistics 2016-12-05 Kris Sankaran , Suzanne Tamang , Ami Bhatt

Illicit drug use among teenagers and young adults (TYAs) remains a pressing public health concern, with rising prevalence and long-term impacts on health and well-being. To detect illicit drug use among TYAs, researchers analyze large-scale…

Machine Learning · Computer Science 2025-10-21 Yiyang Li , Zehong Wang , Zhengqing Yuan , Zheyuan Zhang , Keerthiram Murugesan , Chuxu Zhang , Yanfang Ye

Accurate prediction of protein-ligand binding affinity plays a pivotal role in accelerating the discovery of novel drugs and vaccines, particularly for gastrointestinal (GI) diseases such as gastric ulcers, Crohn's disease, and ulcerative…

Machine Learning · Computer Science 2025-11-11 Ziyang Gao , Annie Cheung , Yihao Ou

Blood glucose level monitoring is of great importance, especially for subjects experiencing type 1 diabetes. Accurate monitoring of their blood glucose level prevents dangerous and life-threatening situations that might be experienced by…

Poisoning attacks are a primary threat to machine learning models, aiming to compromise their performance and reliability by manipulating training datasets. This paper introduces a novel attack - Outlier-Oriented Poisoning (OOP) attack,…

Machine Learning · Computer Science 2024-11-04 Anum Paracha , Junaid Arshad , Mohamed Ben Farah , Khalid Ismail

Cocaine addiction is a psychosocial disorder induced by the chronic use of cocaine and causes a large of number deaths around the world. Despite many decades' effort, no drugs have been approved by the Food and Drug Administration (FDA) for…

Molecular Networks · Quantitative Biology 2022-01-04 Hongsong Feng , Kaifu Gao , Dong Chen , Alfred J Robison , Edmund Ellsworth , Guo-Wei Wei

The open-world test dataset is often mixed with out-of-distribution (OOD) samples, where the deployed models will struggle to make accurate predictions. Traditional detection methods need to trade off OOD detection and in-distribution (ID)…

Machine Learning · Computer Science 2024-04-25 Xu Shen , Yili Wang , Kaixiong Zhou , Shirui Pan , Xin Wang