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The prevalence of unhealthy eating habits has become an increasingly concerning issue in the United States. However, major food recommendation platforms (e.g., Yelp) continue to prioritize users' dietary preferences over the healthiness of…

Opioid and substance misuse is rampant in the United States today, with the phenomenon known as the "opioid crisis". The relationship between substance use and mental health has been extensively studied, with one possible relationship…

Machine Learning · Computer Science 2023-04-21 Usha Lokala , Orchid Chetia Phukan , Triyasha Ghosh Dastidar , Francois Lamy , Raminta Daniulaityte , Amit Sheth

Dietary intake data are routinely drawn upon to explore diet-health relationships. However, these data are often subject to measurement error, distorting the true relationships. Beyond measurement error, there are likely complex synergistic…

Machine Learning · Computer Science 2025-02-12 Dylan Spicker , Amir Nazemi , Joy Hutchinson , Paul Fieguth , Sharon I. Kirkpatrick , Michael Wallace , Kevin W. Dodd

The adoption of deep learning in healthcare is hindered by their "black box" nature. In this paper, we explore the RETAIN architecture for the task of glusose forecasting for diabetic people. By using a two-level attention mechanism, the…

Machine Learning · Computer Science 2020-09-09 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

The opioid epidemic in the United States claims over 40,000 lives per year, and it is estimated that well over two million Americans have an opioid use disorder. Over-prescription and misuse of prescription opioids play an important role in…

Quantitative Methods · Quantitative Biology 2019-05-03 Jen J. Gong , Abigail Z. Jacobs , Toby E. Stuart , Mathijs de Vaan

Social media platforms have become valuable tools for understanding public health challenges by offering insights into patient behaviors, medication use, and mental health issues. However, analyzing such data remains difficult due to the…

Social and Information Networks · Computer Science 2025-08-15 Muhammad Ahmad , Fida Ullah , Muhammad Usman , Ildar Batyrshin , Grigori Sidorov

Background: Type 2 diabetes mellitus (T2DM) is increasingly recognised as a systemic disease characterised by coordinated dysfunction across metabolic, renal, lipid, and inflammatory pathways. Existing clinical assessments often fail to…

Machine Learning · Computer Science 2026-05-26 Mini Han Wang , Liting Huang , Wei Hong , Boonthawan Wingwon

Avoiding out-of-distribution (OOD) data is critical for training supervised machine learning models in the medical imaging domain. Furthermore, obtaining labeled medical data is difficult and expensive since it requires expert annotators…

Computer Vision and Pattern Recognition · Computer Science 2022-10-05 Suraj Kothawade , Akshit Srivastava , Venkat Iyer , Ganesh Ramakrishnan , Rishabh Iyer

The excessive consumption of marijuana can induce substantial psychological and social consequences. In this investigation, we propose an elucidative framework termed high-order graph attention neural networks (HOGANN) for the…

Neurons and Cognition · Quantitative Biology 2024-09-10 Jun-En Ding , Shihao Yang , Anna Zilverstand , Kaustubh R. Kulkarni , Xiaosi Gu , Feng Liu

Metabolic disorders, particularly type 2 diabetes mellitus (T2DM), represent a significant global health burden, disproportionately impacting genetically predisposed populations such as the Pima Indians (a Native American tribe from south…

Machine Learning · Computer Science 2025-09-24 Iram Wajahat , Amritpal Singh , Fazel Keshtkar , Syed Ahmad Chan Bukhari

Understanding the neurobiology of opioid use disorder (OUD) using resting-state functional magnetic resonance imaging (rs-fMRI) may help inform treatment strategies to improve patient outcomes. Recent literature suggests time-frequency…

Neurons and Cognition · Quantitative Biology 2025-03-12 Ahmed Temtam , Megan A. Witherow , Liangsuo Ma , M. Shibly Sadique , F. Gerard Moeller , Khan M. Iftekharuddin

This paper introduces the OPIAID algorithm, a novel approach for predicting and recommending personalized opioid dosages for individual patients. The algorithm optimizes pain management while minimizing opioid related adverse events (ORADE)…

Our aging population increasingly suffers from multiple chronic diseases simultaneously, necessitating the comprehensive treatment of these conditions. Finding the optimal set of drugs for a combinatorial set of diseases is a combinatorial…

Artificial Intelligence · Computer Science 2016-11-16 Pranjul Yadav , Lisiane Prunelli , Alexander Hoff , Michael Steinbach , Bonnie Westra , Vipin Kumar , Gyorgy Simon

Substance use is a global issue that negatively impacts millions of persons who use drugs (PWUDs). In practice, identifying vulnerable PWUDs for efficient allocation of appropriate resources is challenging due to their complex use patterns…

Background: Computational drug repurposing is a cost- and time-efficient approach that aims to identify new therapeutic targets or diseases (indications) of existing drugs/compounds. It is especially critical for emerging and/or orphan…

Quantitative Methods · Quantitative Biology 2023-04-26 Chunyu Ma , Zhihan Zhou , Han Liu , David Koslicki

Dietary studies showed that dietary-related problem such as obesity is associated with other chronic diseases like hypertension, irregular blood sugar levels, and increased risk of heart attacks. The primary cause of these problems is poor…

Computer Vision and Pattern Recognition · Computer Science 2021-09-07 Ghalib Tahir , Chu Kiong Loo

Motivation: Predicting Drug-Target Interaction (DTI) is a well-studied topic in bioinformatics due to its relevance in the fields of proteomics and pharmaceutical research. Although many machine learning methods have been successfully…

Quantitative Methods · Quantitative Biology 2021-07-14 Haiyang Wang , Guangyu Zhou , Siqi Liu , Jyun-Yu Jiang , Wei Wang

People with diabetes need insulin delivery to effectively manage their blood glucose levels, especially after meals, because their bodies either do not produce enough insulin or cannot fully utilize it. Accurate insulin delivery starts with…

Systems and Control · Electrical Eng. & Systems 2024-11-21 Hanyu Zeng , Hui Ji , Pengfei Zhou

Clinical dietary assessment can generate detailed but high-dimensional nutrient and food-group information that is difficult to translate quickly into counselling priorities. This paper proposes an explainable unsupervised-to-supervised…

Quantitative Methods · Quantitative Biology 2026-05-12 Wing Yi Yu , Chun Yin Chiu

The opioid crisis remains one of the most daunting and complex public health problems in the United States. This study investigates the national epidemic by analyzing vulnerability profiles of three key factors: opioid-related mortality…