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Cone beam CT (CBCT) has been widely used for patient setup in image guided radiation therapy (IGRT). Radiation dose from CBCT scans has become a clinical concern. The purposes of this study are 1) to commission a GPU-based Monte Carlo (MC)…

Proton therapy is a cancer treatment technique currently in growth worldwide. It offers advantages with respect to conventional X-ray and $\gamma$-ray radiotherapy, in particular, a better control of the dose deposition allowing to reach a…

Generative modelling and synthetic data can be a surrogate for real medical imaging datasets, whose scarcity and difficulty to share can be a nuisance when delivering accurate deep learning models for healthcare applications. In recent…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Virginia Fernandez , Walter Hugo Lopez Pinaya , Pedro Borges , Mark S. Graham , Tom Vercauteren , M. Jorge Cardoso

Complete and high-quality multi-modal Magnetic Resonance Imaging (MRI) is essential for accurate neuro-oncological assessment, as each contrast provides complementary anatomical and pathological information. However, acquiring all…

Image and Video Processing · Electrical Eng. & Systems 2026-05-04 Zaid A. Abod , Furqan Aziz

Objective: Four-dimensional computed tomography (4DCT) imaging consists in reconstructing a CT acquisition into multiple phases to track internal organ and tumor motion. It is commonly used in radiotherapy treatment planning to establish…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Yi-Heng Cao , Vincent Bourbonne , François Lucia , Ulrike Schick , Julien Bert , Vincent Jaouen , Dimitris Visvikis

With the advent of Deep Learning (DL) techniques, especially Generative Adversarial Networks (GANs), data augmentation and generation are quickly evolving domains that have raised much interest recently. However, the DL techniques are data…

Computer Vision and Pattern Recognition · Computer Science 2018-05-30 Umair Javaid , John A. Lee

This paper presents the winning solution of task 1 and the third-placed solution of task 3 of the BraTS challenge. The use of automated tools in clinical practice has increased due to the development of more and more sophisticated and…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 André Ferreira , Tiago Jesus , Behrus Puladi , Jens Kleesiek , Victor Alves , Jan Egger

In this work, we present a method for synthetic CT (sCT) generation from zero-echo-time (ZTE) MRI aimed at structural and quantitative accuracies of the image, with a particular focus on the accurate bone density value prediction. We…

Despite its benefits for tumour detection and treatment, the administration of contrast agents in dynamic contrast-enhanced MRI (DCE-MRI) is associated with a range of issues, including their invasiveness, bioaccumulation, and a risk of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-03 Richard Osuala , Smriti Joshi , Apostolia Tsirikoglou , Lidia Garrucho , Walter H. L. Pinaya , Oliver Diaz , Karim Lekadir

Advancements in AI for medical imaging offer significant potential. However, their applications are constrained by the limited availability of data and the reluctance of medical centers to share it due to patient privacy concerns.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Marvin Seyfarth , Salman Ul Hassan Dar , Isabelle Ayx , Matthias Alexander Fink , Stefan O. Schoenberg , Hans-Ulrich Kauczor , Sandy Engelhardt

Radiation therapy is a primary and effective NasoPharyngeal Carcinoma (NPC) treatment strategy. The precise delineation of Gross Tumor Volumes (GTVs) and Organs-At-Risk (OARs) is crucial in radiation treatment, directly impacting patient…

Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART) to account for anatomical changes. Conventional intensity-based DIR methods often fail when image intensities differ. This study evaluates a hybrid…

Medical Physics · Physics 2024-11-27 Keyur D. Shah , James A. Shackleford , Nagarajan Kandasamy , Gregory C. Sharp

We summarize recent results and ongoing activities in mathematical algorithms and computer science methods related to proton computed tomography (pCT) and intensity-modulated particle therapy (IMPT) treatment planning. Proton therapy…

Medical Physics · Physics 2021-08-24 Yair Censor , Keith E. Schubert , Reinhard W. Schulte

Deep learning has emerged as a powerful artificial intelligence tool to interpret medical images for a growing variety of applications. However, the paucity of medical imaging data with high-quality annotations that is necessary for…

Computer Vision and Pattern Recognition · Computer Science 2018-10-02 Faisal Mahmood , Richard Chen , Sandra Sudarsky , Daphne Yu , Nicholas J. Durr

Generative models have been very successful over the years and have received significant attention for synthetic data generation. As deep learning models are getting more and more complex, they require large amounts of data to perform…

Image and Video Processing · Electrical Eng. & Systems 2023-02-24 Usama Tariq , Rizwan Qureshi , Anas Zafar , Danyal Aftab , Jia Wu , Tanvir Alam , Zubair Shah , Hazrat Ali

Defective and inconsistent responses in CT detectors can cause ring and streak artifacts in the reconstructed images, making them unusable for clinical purposes. In recent years, several ring artifact reduction solutions have been proposed…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Hongxu Yang , Levente Lippenszky , Edina Timko , Gopal Avinash

Accurate dose calculation on cone beam computed tomography (CBCT) images is essential for modern proton treatment planning workflows, particularly when accounting for inter-fractional anatomical changes in adaptive treatment scenarios.…

Training computer-vision related algorithms on medical images for disease diagnosis or image segmentation is difficult due to the lack of training data, labeled samples, and privacy concerns. For this reason, a robust generative method to…

Image and Video Processing · Electrical Eng. & Systems 2021-11-04 Robert V Bergen , Jean-Francois Rajotte , Fereshteh Yousefirizi , Ivan S Klyuzhin , Arman Rahmim , Raymond T. Ng

7 Tesla (7T) apparent diffusion coefficient (ADC) maps derived from diffusion-weighted imaging (DWI) demonstrate improved image quality and spatial resolution over 3 Tesla (3T) ADC maps. However, 7T magnetic resonance imaging (MRI)…

Medical Physics · Physics 2023-11-28 Zach Eidex , Jing Wang , Mojtaba Safari , Eric Elder , Jacob Wynne , Tonghe Wang , Hui-Kuo Shu , Hui Mao , Xiaofeng Yang

In the United States, skin cancer ranks as the most commonly diagnosed cancer, presenting a significant public health issue due to its high rates of occurrence and the risk of serious complications if not caught early. Recent advancements…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Chi-en Amy Tai , Oustan Ding , Alexander Wong