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Automated synthesis of histology images has several potential applications in computational pathology. However, no existing method can generate realistic tissue images with a bespoke cellular layout or user-defined histology parameters. In…

Image and Video Processing · Electrical Eng. & Systems 2022-12-29 Srijay Deshpande , Muhammad Dawood , Fayyaz Minhas , Nasir Rajpoot

Due to its wide field of view, cone-beam computed tomography (CBCT) is plagued by large amounts of scatter, where attenuated photons hit the detector, and corrupt the linear models used for reconstruction. Given that one can generate a good…

Medical Physics · Physics 2017-07-06 Jonathan Mason , Alessandro Perelli , William Nailon , Mike Davies

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Computed tomography (CT) is a widely-used imaging technology that assists clinical decision-making with high-quality human body representations. To reduce the radiation dose posed by CT, sparse-view and limited-angle CT are developed with…

Image and Video Processing · Electrical Eng. & Systems 2022-11-04 Ce Wang , Kun Shang , Haimiao Zhang , Shang Zhao , Dong Liang , S. Kevin Zhou

The number of cancer cases per year is rapidly increasing worldwide. In radiation therapy (RT), radiation from linear accelerators is used to kill malignant tumor cells. Scheduling patients for RT is difficult both due to the numerous…

Optimization and Control · Mathematics 2023-03-21 Sara Frimodig , Per Enqvist , Jan Kronqvist

Computed Tomography (CT) is a vital diagnostic tool in clinical practice, yet the health risks associated with ionizing radiation cannot be overlooked. Low-dose CT (LDCT) helps mitigate radiation exposure but simultaneously leads to reduced…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Guoliang Gong , Man Yu

With the development of computed tomography (CT) imaging technology, it is possible to acquire multi-energy data by spectral CT. Being different from conventional CT, the X-ray energy spectrum of spectral CT is cutting into several narrow…

Medical Physics · Physics 2023-01-25 Yuanwei He , Li Zeng , Qiong Xu , Zhe Wang , Haijun Yu , Zhaoqiang Shen , Zhaojun Yang , Rifeng Zhou

Deep-learning-based MR-to-CT synthesis can estimate the electron density of tissues, thereby facilitating PET attenuation correction in whole-body PET/MR imaging. However, whole-body MR-to-CT synthesis faces several challenges including the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Jiaxu Zheng , Zhenrong Shen , Lichi Zhang , Qun Chen

Skin cancer is one of the most common cancers worldwide and early detection is critical for effective treatment. However, current AI diagnostic tools are often trained on datasets dominated by lighter skin tones, leading to reduced accuracy…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Areez Muhammed Shabu , Mohammad Samar Ansari , Asra Aslam

Accurate lesion segmentation in whole-body PET/CT scans is crucial for cancer diagnosis and treatment planning, but limited datasets often hinder the performance of automated segmentation models. In this paper, we explore the potential of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Lap Yan Lennon Chan , Chenxin Li , Yixuan Yuan

Computer-aided diagnosis (CAD) based on histopathological imaging has progressed rapidly in recent years with the rise of machine learning based methodologies. Traditional approaches consist of training a classification model using features…

Computer Vision and Pattern Recognition · Computer Science 2019-03-29 Junaid Malik , Serkan Kiranyaz , Suchitra Kunhoth , Turker Ince , Somaya Al-Maadeed , Ridha Hamila , Moncef Gabbouj

Radiotherapy (RT) is a critical cancer treatment, with volumetric modulated arc therapy (VMAT) being a commonly used technique that enhances dose conformity by dynamically adjusting multileaf collimator (MLC) positions and monitor units…

Medical Physics · Physics 2025-06-26 Stefanos Achlatis , Efstratios Gavves , Jan-Jakob Sonke

Objective: Radiotherapy uses precise doses of radiation to treat cancer, requiring accurate verification, e.g. using the Electronic Portal Imaging Device (EPID), to guide treatment. To develop an effective artificial intelligence (AI) model…

Image and Video Processing · Electrical Eng. & Systems 2024-10-04 Olga Glazunova , Cecile J. A. Wolfs , Frank Verhaegen

Deep learning has shown excellent performance in analysing medical images. However, datasets are difficult to obtain due privacy issues, standardization problems, and lack of annotations. We address these problems by producing realistic…

Computer Vision and Pattern Recognition · Computer Science 2023-07-24 Enric Moreu , Eric Arazo , Kevin McGuinness , Noel E. O'Connor

Deep learning-based Generative Models have the potential to convert low-resolution CT images into high-resolution counterparts without long acquisition times and increased radiation exposure in thin-slice CT imaging. However, procuring…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Zeyu Tang , Xiaodan Xing , Guang Yang

Magnetic Resonance Imaging (MRI) is instrumental in clinical diagnosis, offering diverse contrasts that provide comprehensive diagnostic information. However, acquiring multiple MRI contrasts is often constrained by high costs, long…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Sanuwani Dayarathna , Kh Tohidul Islam , Bohan Zhuang , Guang Yang , Jianfei Cai , Meng Law , Zhaolin Chen

Magnetic resonance (MR)-guided radiation therapy (RT) is enhancing head and neck cancer (HNC) treatment through superior soft tissue contrast and longitudinal imaging capabilities. However, manual tumor segmentation remains a significant…

Magnetic resonance imaging (MRI) inpainting supports numerous clinical and research applications. We introduce the first generative model that conditions on voxel-level, continuous tumor concentrations to synthesize high-fidelity brain…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Valentin Biller , Lucas Zimmer , Ayhan Can Erdur , Sandeep Nagar , Daniel Rückert , Niklas Bubeck , Jonas Weidner

Medical imaging faces challenges such as limited spatial resolution, interference from electronic noise and poor contrast-to-noise ratios. Photon Counting Computed Tomography (PCCT) has emerged as a solution, addressing these issues with…

Image and Video Processing · Electrical Eng. & Systems 2024-02-08 Ana Carolina Alves , André Ferreira , Gijs Luijten , Jens Kleesiek , Behrus Puladi , Jan Egger , Victor Alves

Tumor is a leading cause of death worldwide, with an estimated 10 million deaths attributed to tumor-related diseases every year. AI-driven tumor recognition unlocks new possibilities for more precise and intelligent tumor screening and…