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We study nonlinear reactive transport in a layered porous medium separated by an $\varepsilon$-thin, highly heterogeneous fracture whose aperture and obstacle pattern vary periodically. Species transport in the bulk is governed by parabolic…

Analysis of PDEs · Mathematics 2026-02-19 Taras Mel'nyk , Sorin Pop , Christian Rohde

For the quite extensively developed PDE backstepping methodology for coupled linear hyperbolic PDEs, we provide a generalization from finite collections of such PDEs, whose states at each location in space are vector-valued, to previously…

Analysis of PDEs · Mathematics 2024-08-27 Valentin Alleaume , Miroslav Krstic

In this paper we consider the multiscale modelling of water transport in vegetated soil. In the microscopic model we distinguish between subdomains of soil and plant tissue, and use the Richards equation to model the water transport through…

Analysis of PDEs · Mathematics 2024-11-05 Andrew Mair , Mariya Ptashnyk

Transportation processes, which play a prominent role in the life and social sciences, are typically described by discrete models on lattices. For studying their dynamics a continuous formulation of the problem via partial differential…

Symbolic Computation · Computer Science 2016-03-22 Christoph Koutschan , Helene Ranetbauer , Georg Regensburger , Marie-Therese Wolfram

The problem of reconstructing and identifying intracellular protein signaling and biochemical networks is of critical importance in biology today. We sought to develop a mathematical approach to this problem using, as a test case, one of…

Data Analysis, Statistics and Probability · Physics 2012-06-15 D. Napoletani , T. Sauer , D. C. Struppa , E. Petricoin , L. Liotta

We leverage powerful mathematical tools stemming from optimal transport theory and transform them into an efficient algorithm to reconstruct the fluctuations of the primordial density field, built on solving the Monge-Amp\`ere-Kantorovich…

Cosmology and Nongalactic Astrophysics · Physics 2021-07-14 Bruno Lévy , Roya Mohayaee , Sebastian von Hausegger

We present new analytical and numerical results for the elliptic-parabolic system of partial differential equations proposed by Hu and Cai, which models the formation of biological transport networks. The model describes the pressure field…

Analysis of PDEs · Mathematics 2015-10-14 Jan Haskovec , Peter Markowich , Benoit Perthame , Matthias Schlottbom

During the upstroke of a normal eye blink, the upper lid moves and paints a thin tear film over the exposed corneal and conjunctival surfaces. This thin tear film may be modeled by a nonlinear fourth-order PDE derived from lubrication…

Numerical Analysis · Mathematics 2017-04-07 Tobin A. Driscoll , Richard J. Braun , Joseph K. Brosch

The state reconstruction problem of a heterogeneous dynamic system under sporadic measurements is considered. This system consists of a conversation flow together with a multi-agent network modeling particles within the flow. We propose a…

Optimization and Control · Mathematics 2021-04-28 M. Barreau , J. Liu , K. H. Johansson

The mechanical properties of tissues play an essential role for all tissue properties such as cell division, and differentiation or morphogenesis. Here, we study theoretically the rheology of 2-dimensional epithelial tissues described by a…

Soft Condensed Matter · Physics 2023-12-18 Doron Grossman , Jean-Francois Joanny

For a biological system to grow and expand, mass must be transferred from the environment to the system and be assimilated into its reaction network. Here, I characterize the biomass transfer process for growing autocatalytic systems. By…

Molecular Networks · Quantitative Biology 2026-02-05 Wei-Hsiang Lin

Driven by the need to accelerate numerical simulations, the use of machine learning techniques is rapidly growing in the field of computational solid mechanics. Their application is especially advantageous in concurrent multiscale finite…

Numerical Analysis · Mathematics 2023-03-22 M. A. Maia , I. B. C. M. Rocha , P. Kerfriden , F. P. van der Meer

Many living and physical systems such as cell aggregates, tissues or bacterial colonies behave as unconventional systems of particles that are strongly constrained by volume exclusion and shape interactions. Understanding how these…

Quantitative Methods · Quantitative Biology 2026-05-20 Antoine Diez , Jean Feydy

A coupled hygro-thermo-mechanical computational model is proposed for fibre reinforced polymers, formulated within the framework of Computational Homogenisation (CH). At each macrostructure Gauss point, constitutive matrices for thermal,…

Computational Engineering, Finance, and Science · Computer Science 2016-10-14 Zahur Ullah , Lukasz Kaczmarczyk , Sotirios Grammatikos , Mark Evernden , Chris Pearce

We extend the stochastic reconstruction theorem to a setting where the underlying family of distributions satisfies some natural conditions involving rectangular increments. This allows us to prove the well-posedness of a new class of mixed…

Probability · Mathematics 2025-11-13 Carlo Bellingeri , Hannes Kern

In this paper we introduce CorticalFlow, a new geometric deep-learning model that, given a 3-dimensional image, learns to deform a reference template towards a targeted object. To conserve the template mesh's topological properties, we…

Computer Vision and Pattern Recognition · Computer Science 2022-06-07 Léo Lebrat , Rodrigo Santa Cruz , Frédéric de Gournay , Darren Fu , Pierrick Bourgeat , Jurgen Fripp , Clinton Fookes , Olivier Salvado

In this paper, we derive upscaled equations for modelling biofilm growth in porous media. The resulting macro-scale mathematical models consider permeable multi-species biofilm including water flow, transport, detachment and reactions. The…

Cell deformability is an essential determinant for tissue-scale mechanical nature, such as fluidity and rigidity, and is thus crucial for understanding tissue homeostasis and stable developmental processes. However, numerical simulations…

Tissues and Organs · Quantitative Biology 2023-03-08 Nen Saito , Shuji Ishihara

We deduce a model for glioma invasion making use of DTI data and accounting for the dynamics of brain tissue being actively degraded by tumor cells via excessive acidity production, but also according to the local orientation of tissue…

Tissues and Organs · Quantitative Biology 2020-06-23 G. Corbin , C. Engwer , A. Klar , J. Nieto , J. Soler , C. Surulescu , M. Wenske

Next generation in-to-out-of body biomedical applications have adopted optical wireless communications (OWCs). However, by delving into the published literature, a gap is recognised in modeling the in-to-out-of channel, since most published…