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One of the notable fields in studying the genetics of cancer is disease gene identification which affects disease treatment and drug discovery. Many researches have been done in this field. Genome-wide association studies (GWAS) are one of…

Computational Engineering, Finance, and Science · Computer Science 2016-04-27 Zahra Razaghi-Moghadama , Razieh Abdollahia , Sama Goliaeib , Morteza Ebrahimia

The rapid progress in quantum computing has opened up new possibilities for tackling complex scientific problems. Variational quantum eigensolver (VQE) holds the potential to solve quantum chemistry problems and achieve quantum advantages.…

Quantum Physics · Physics 2024-03-08 Linghua Zhu , Senwei Liang , Chao Yang , Xiaosong Li

Quantum Machine Learning (QML) offers tremendous potential but is currently limited by the availability of qubits. We introduce an innovative approach that utilizes pre-trained neural networks to enhance Variational Quantum Circuits (VQC).…

Machine Learning · Computer Science 2024-11-14 Jun Qi , Chao-Han Yang , Samuel Yen-Chi Chen , Pin-Yu Chen , Hector Zenil , Jesper Tegner

Quantum machine learning is a rapidly growing field at the intersection of quantum computing and machine learning. In this work, we examine our quantum machine learning models, which are based on quantum support vector classification (QSVC)…

Quantum Physics · Physics 2024-05-02 Teppei Suzuki , Takashi Hasebe , Tsubasa Miyazaki

Quantum machine learning (QML) has witnessed immense progress recently, with quantum support vector machines (QSVMs) emerging as a promising model. This paper focuses on the two existing QSVM methods: quantum kernel SVM (QK-SVM) and quantum…

Quantum Physics · Physics 2024-02-02 Nouhaila Innan , Muhammad Al-Zafar Khan , Biswaranjan Panda , Mohamed Bennai

Quantum computers promise scalable treatments of electronic structure, yet applying variational quantum eigensolvers (VQE) on realistic drug-like molecules remains constrained by the performance limitations of near-term quantum hardwares. A…

Chemical Physics · Physics 2025-12-23 Zhi Yin , Xiaoran Li , Zhupeng Han , Shengyu Zhang , Xin Li , Zhihong Zhang , Runqing Zhang , Anbang Wang , Xiaojin Zhang

Vector Quantisation (VQ) is experiencing a comeback in machine learning, where it is increasingly used in representation learning. However, optimizing the codevectors in existing VQ-VAE is not entirely trivial. A problem is codebook…

Computer Vision and Pattern Recognition · Computer Science 2023-07-31 Chuanxia Zheng , Andrea Vedaldi

Quantum error mitigation (QEM) is crucial for obtaining reliable results on quantum computers by suppressing quantum noise with moderate resources. It is a key factor for successful and practical quantum algorithm implementations in the…

Quantum Physics · Physics 2023-08-28 Shi-Xin Zhang , Zhou-Quan Wan , Chang-Yu Hsieh , Hong Yao , Shengyu Zhang

Bayesian Neural Networks (BNNs) provide principled uncertainty quantification but suffer from substantial computational and memory overhead compared to deterministic networks. While quantization techniques have successfully reduced resource…

Machine Learning · Computer Science 2025-12-12 Hendrik Borras , Yong Wu , Bernhard Klein , Holger Fröning

We introduce an optimisation method for variational quantum algorithms and experimentally demonstrate a 100-fold improvement in efficiency compared to naive implementations. The effectiveness of our approach is shown by obtaining…

Variational quantum approaches have shown great promise in finding near-optimal solutions to computationally challenging tasks. Nonetheless, enforcing constraints in a disciplined fashion has been largely unexplored. To address this gap,…

Quantum Physics · Physics 2024-04-30 Thinh Viet Le , Vassilis Kekatos

Personalized cancer treatment requires a thorough understanding of complex interactions between drugs and cancer cell lines in varying genetic and molecular contexts. To address this, high-throughput screening has been used to generate…

Machine Learning · Computer Science 2023-07-03 Vishal Dey , Xia Ning

Graph Neural Networks (GNNs) have emerged as a prominent class of data-driven methods for molecular property prediction. However, a key limitation of typical GNN models is their inability to quantify uncertainties in the predictions. This…

Machine Learning · Computer Science 2024-07-02 Shengli Jiang , Shiyi Qin , Reid C. Van Lehn , Prasanna Balaprakash , Victor M. Zavala

The detection of cardiovascular diseases (CVD) using machine learning techniques represents a significant advancement in medical diagnostics, aiming to enhance early detection, accuracy, and efficiency. This study explores a comparative…

Machine Learning · Computer Science 2024-05-28 Dayana K , S. Nandini , Sanjjushri Varshini R

Variational quantum algorithms (VQAs) are widely speculated to deliver quantum advantages for practical problems under the quantum-classical hybrid computational paradigm in the near term. Both theoretical and practical developments of VQAs…

Quantum Physics · Physics 2021-12-17 Shi-Xin Zhang , Chang-Yu Hsieh , Shengyu Zhang , Hong Yao

Quantum Machine Learning (QML) is considered one of the most promising applications of Quantum Computing in the Noisy Intermediate Scale Quantum (NISQ) era for the impact it is thought to have in the near future. Although promising…

Quantum Physics · Physics 2025-08-22 Valeria Repetto , Elia Giuseppe Ceroni , Giuseppe Buonaiuto , Romina D'Aurizio

Quantum computing (QC) provides a promising avenue toward enabling quantum chemistry calculations, which are classically impossible due to a computational complexity that increases exponentially with system size. As fully fault-tolerant…

Precise quantum expectation values are crucial for quantum algorithm development, but noise in real-world systems can degrade these estimations. While quantum error correction is resource-intensive, error mitigation strategies offer a…

Quantum Physics · Physics 2025-01-31 Touheed Anwar Atif , Reuben Blake Tate , Stephan Eidenbenz

The digitization of healthcare presents numerous challenges, including the complexity of biological systems, vast data generation, and the need for personalized treatment plans. Traditional computational methods often fall short, leading to…

Emerging Technologies · Computer Science 2025-07-25 Markus Bertl , Alan Mott , Salvatore Sinno , Bhavika Bhalgamiya

Variational inference provides approximations to the computationally intractable posterior distribution in Bayesian networks. A prominent medical application of noisy-or Bayesian network is to infer potential diseases given observed…

Machine Learning · Computer Science 2016-05-23 Yusheng Xie , Nan Du , Wei Fan , Jing Zhai , Weicheng Zhu