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Multimodal learning combining pathology images and genomic sequences enhances cancer survival analysis but faces clinical implementation barriers due to limited access to genomic sequencing in under-resourced regions. To enable survival…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Zizhi Chen , Minghao Han , Xukun Zhang , Shuwei Ma , Tao Liu , Xing Wei , Lihua Zhang

The nexus of quantum computing and machine learning - quantum machine learning - offers the potential for significant advancements in chemistry. This review specifically explores the potential of quantum neural networks on gate-based…

Effective clustering of biomedical data is crucial in precision medicine, enabling accurate stratifiction of patients or samples. However, the growth in availability of high-dimensional categorical data, including `omics data, necessitates…

Machine Learning · Statistics 2026-03-03 Jackie Rao , Paul D. W. Kirk

Variational Quantum Algorithms (VQAs) are a promising approach to leverage Noisy Intermediate-Scale Quantum (NISQ) computers. However, choosing optimal quantum circuits that efficiently solve a given VQA problem is a non-trivial task.…

Quantum Physics · Physics 2025-10-07 Swagat Kumar , Jan-Nico Zaech , Colin Michael Wilmott , Luc Van Gool

Stress can increase the possibility of cognitive impairment and decrease the quality of life in older adults. Smart healthcare can deploy quantum machine learning to enable preventive and diagnostic support. This work introduces a unique…

Quantum Physics · Physics 2025-01-10 Md Saif Hassan Onim , Travis S. Humble , Himanshu Thapliyal

The emerging field of precision oncology relies on the accurate pinpointing of alterations in the molecular profile of a tumor to provide personalized targeted treatments. Current methodologies in the field commonly include the application…

Due to cancer's complex nature and variable response to therapy, precision oncology informed by omics sequence analysis has become the current standard of care. However, the amount of data produced for each patients makes it difficult to…

Machine Learning · Computer Science 2023-10-30 Patrick J. Lawrence , Xia Ning

Defining and separating cancer subtypes is essential for facilitating personalized therapy modality and prognosis of patients. The definition of subtypes has been constantly recalibrated as a result of our deepened understanding. During…

Machine Learning · Computer Science 2022-07-21 Zheng Chen , Ziwei Yang , Lingwei Zhu , Guang Shi , Kun Yue , Takashi Matsubara , Shigehiko Kanaya , MD Altaf-Ul-Amin

Quantifying the dynamics of tumor burden reveals useful information about cancer evolution concerning treatment effects and drug resistance, which play a crucial role in advancing model-informed drug developments (MIDD) towards personalized…

Other Quantitative Biology · Quantitative Biology 2023-01-10 Nam Nguyen , Kwang-Cheng Chen

We propose the molecular omics network (MOOMIN) a multimodal graph neural network used by AstraZeneca oncologists to predict the synergy of drug combinations for cancer treatment. Our model learns drug representations at multiple scales…

Machine Learning · Computer Science 2022-08-09 Benedek Rozemberczki , Anna Gogleva , Sebastian Nilsson , Gavin Edwards , Andriy Nikolov , Eliseo Papa

Variational Quantum Algorithms (VQAs) are a leading approach for near-term quantum computing but face major optimization challenges from noise, barren plateaus, and complex energy landscapes. We benchmarked more than fifty metaheuristic…

Quantum Physics · Physics 2025-09-30 Vojtěch Novák , Ivan Zelinka , Václav Snášel

Accurate and reliable diagnosis of diseases is crucial in enabling timely medical treatment and enhancing patient survival rates. In recent years, Machine Learning has revolutionized diagnostic practices by creating classification models…

Machine Learning · Computer Science 2025-12-02 Antonio Tudisco , Deborah Volpe , Giovanna Turvani

Artificial intelligence and machine learning paves the way to achieve greater technical feats. In this endeavor to hone these techniques, quantum machine learning is budding to serve as an important tool. Using the techniques of deep…

The study and prediction of chemical reactivity is one of the most important application areas of molecular quantum chemistry. Large-scale, fully error-tolerant quantum computers could provide exact or near-exact solutions to the underlying…

Quantum Physics · Physics 2019-09-12 Michael Kühn , Sebastian Zanker , Peter Deglmann , Michael Marthaler , Horst Weiß

There has been much recent interest in near-term applications of quantum computers, i.e., using quantum circuits that have short decoherence times due to hardware limitations. Variational quantum algorithms (VQA), wherein an optimization…

Quantum Physics · Physics 2024-10-16 Vyacheslav Kungurtsev , Georgios Korpas , Jakub Marecek , Elton Yechao Zhu

Quantum neural networks (QNNs) play an important role as an emerging technology in the rapidly growing field of quantum machine learning. While their empirical success is evident, the theoretical explorations of QNNs, particularly their…

Machine Learning · Computer Science 2025-02-05 Jiaqi Yang , Wei Xie , Xiaohua Xu

Quantum computing holds promise across various fields, particularly with the advent of Noisy Intermediate-Scale Quantum (NISQ) devices, which can outperform classical supercomputers in specific tasks. However, challenges such as noise and…

Drug discovery remains a slow and expensive process that involves many steps, from detecting the target structure to obtaining approval from the Food and Drug Administration (FDA), and is often riddled with safety concerns. Accurate…

Quantitative Methods · Quantitative Biology 2025-08-22 Ali Vefghi , Zahed Rahmati , Mohammad Akbari

Variational quantum algorithms have found success in the NISQ era owing to their hybrid quantum-classical approach which mitigate the problems of noise in quantum computers. In our study we introduce the dynamic ansatz in the Variational…

Quantum Physics · Physics 2022-02-08 Hrushikesh Patil , Yulun Wang , Predrag Krstic

Emerging reinforcement learning techniques using deep neural networks have shown great promise in control optimization. They harness non-local regularities of noisy control trajectories and facilitate transfer learning between tasks. To…

Quantum Physics · Physics 2018-04-17 Murphy Yuezhen Niu , Sergio Boixo , Vadim Smelyanskiy , Hartmut Neven