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In recent years, advancements in natural language processing (NLP) have been fueled by deep learning techniques, particularly through the utilization of powerful computing resources like GPUs and TPUs. Models such as BERT and GPT-3, trained…

Computation and Language · Computer Science 2024-02-27 Shuning Huo , Yafei Xiang , Hanyi Yu , Mengran Zhu , Yulu Gong

In this paper, we study how to improve the zero-shot reasoning ability of large language models~(LLMs) over structured data in a unified way. Inspired by the study on tool augmentation for LLMs, we develop an \emph{Iterative…

Computation and Language · Computer Science 2023-10-24 Jinhao Jiang , Kun Zhou , Zican Dong , Keming Ye , Wayne Xin Zhao , Ji-Rong Wen

In the rapidly evolving landscape of genomics, deep learning has emerged as a useful tool for tackling complex computational challenges. This review focuses on the transformative role of Large Language Models (LLMs), which are mostly based…

Genetic programming (GP) has the potential to generate explainable results, especially when used for dimensionality reduction. In this research, we investigate the potential of leveraging eXplainable AI (XAI) and large language models…

Neural and Evolutionary Computing · Computer Science 2024-03-07 Paula Maddigan , Andrew Lensen , Bing Xue

This paper demonstrates that language models are strong structure-based protein designers. We present LM-Design, a generic approach to reprogramming sequence-based protein language models (pLMs), that have learned massive sequential…

Machine Learning · Computer Science 2023-02-10 Zaixiang Zheng , Yifan Deng , Dongyu Xue , Yi Zhou , Fei YE , Quanquan Gu

Chain of thought prompting successfully improves the reasoning capabilities of large language models, achieving state of the art results on a range of datasets. However, these reasoning capabilities only appear to emerge in models with a…

Computation and Language · Computer Science 2023-06-02 Lucie Charlotte Magister , Jonathan Mallinson , Jakub Adamek , Eric Malmi , Aliaksei Severyn

The number and complexity of artificial intelligence (AI) applications is growing relentlessly. As a result, even with the many algorithmic and mathematical advances experienced over past decades as well as the impressive energy efficiency…

Machine Learning · Computer Science 2023-12-18 Jose Duato , Jose I. Mestre , Manuel F. Dolz , Enrique S. Quintana-Ortí

Artificial intelligence has been applied in various aspects of online education to facilitate teaching and learning. However, few approaches has been made toward a complete AI-powered tutoring system. In this work, we explore the…

Human-Computer Interaction · Computer Science 2024-08-06 Yulin Chen , Ning Ding , Hai-Tao Zheng , Zhiyuan Liu , Maosong Sun , Bowen Zhou

Chain-of-thought (CoT) reasoning has enabled large language models (LLMs) to utilize additional computation through intermediate tokens to solve complex tasks. However, we posit that typical reasoning traces contain many redundant tokens,…

Computation and Language · Computer Science 2025-06-11 Tergel Munkhbat , Namgyu Ho , Seo Hyun Kim , Yongjin Yang , Yujin Kim , Se-Young Yun

Large language models (LLMs) such as ChatGPT have gained considerable interest across diverse research communities. Their notable ability for text completion and generation has inaugurated a novel paradigm for language-interfaced problem…

Quantitative Methods · Quantitative Biology 2024-02-22 Hengchuang Yin , Zhonghui Gu , Fanhao Wang , Yiparemu Abuduhaibaier , Yanqiao Zhu , Xinming Tu , Xian-Sheng Hua , Xiao Luo , Yizhou Sun

Large Language Models (LLMs) excel in diverse areas, yet struggle with complex scientific reasoning, especially in the field of chemistry. Different from the simple chemistry tasks (e.g., molecule classification) addressed in previous…

Computation and Language · Computer Science 2024-02-12 Siru Ouyang , Zhuosheng Zhang , Bing Yan , Xuan Liu , Yejin Choi , Jiawei Han , Lianhui Qin

Large language models~(LLM) like ChatGPT have become indispensable to artificial general intelligence~(AGI), demonstrating excellent performance in various natural language processing tasks. In the real world, graph data is ubiquitous and…

Artificial Intelligence · Computer Science 2023-07-12 Jiayan Guo , Lun Du , Hengyu Liu , Mengyu Zhou , Xinyi He , Shi Han

Pretraining DNA language models (DNALMs) on the full human genome is resource-intensive, yet often considered necessary for strong downstream performance. Inspired by recent findings in NLP and long-context modeling, we explore an…

Genomics · Quantitative Biology 2025-06-24 Sohan Mupparapu , Parameswari Krishnamurthy , Ratish Puduppully

Recent advances in Large Language Models (LLMs) have presented new opportunities for integrating Artificial General Intelligence (AGI) into biological research and education. This study evaluated the capabilities of leading LLMs, including…

Computation and Language · Computer Science 2023-11-15 Xinyu Gong , Jason Holmes , Yiwei Li , Zhengliang Liu , Qi Gan , Zihao Wu , Jianli Zhang , Yusong Zou , Yuxi Teng , Tian Jiang , Hongtu Zhu , Wei Liu , Tianming Liu , Yajun Yan

The adaptation of Large Language Models like ChatGPT for information retrieval from scientific data, software and publications is offering new opportunities to simplify access to and understanding of science for persons from all levels of…

Instrumentation and Methods for Astrophysics · Physics 2025-01-14 Jutta Schnabel

Recent works have shown that chain-of-thought (CoT) prompting can elicit language models to solve complex reasoning tasks, step-by-step. However, prompt-based CoT methods are dependent on very large models such as GPT-3 175B which are…

Computation and Language · Computer Science 2023-06-14 Namgyu Ho , Laura Schmid , Se-Young Yun

This study is a pioneering endeavor to investigate the capabilities of Large Language Models (LLMs) in addressing conceptual questions within the domain of mechanical engineering with a focus on mechanics. Our examination involves a…

Computation and Language · Computer Science 2024-01-25 Jie Tian , Jixin Hou , Zihao Wu , Peng Shu , Zhengliang Liu , Yujie Xiang , Beikang Gu , Nicholas Filla , Yiwei Li , Ning Liu , Xianyan Chen , Keke Tang , Tianming Liu , Xianqiao Wang

Inspired by the success of large language models (LLM) for DNA and proteins, several LLM for RNA have been developed recently. RNA-LLM uses large datasets of RNA sequences to learn, in a self-supervised way, how to represent each RNA base…

Artificial Intelligence · Computer Science 2025-02-04 L. I. Zablocki , L. A. Bugnon , M. Gerard , L. Di Persia , G. Stegmayer , D. H. Milone

Large language models (LLMs) such as GPT-4 have recently demonstrated impressive results across a wide range of tasks. LLMs are still limited, however, in that they frequently fail at complex reasoning, their reasoning processes are opaque,…

Large Language Models (LLMs) offer numerous applications, the full extent of which is not yet understood. This paper investigates if LLMs can be applied for editing structured and semi-structured documents with minimal effort. Using a…

Machine Learning · Computer Science 2024-09-16 Irene Weber