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Recent advances in cancer research largely rely on new developments in microscopic or molecular profiling techniques offering high level of detail with respect to either spatial or molecular features, but usually not both. Here, we present…

We present an open source Python library for simulating overlapping (i.e., blended) images of galaxies and performing self-consistent comparisons of detection and deblending algorithms based on a suite of metrics. The package, named…

Correlative microscopy is a powerful technique that combines the advantages of multiple imaging modalities to achieve a comprehensive understanding of investigated samples. For example, fluorescence microscopy provides unique functional…

I present a fast Python tool, SpectRes, for carrying out the resampling of spectral flux densities and their associated uncertainties onto different wavelength grids. The function works with any grid of wavelength values, including…

Instrumentation and Methods for Astrophysics · Physics 2017-05-16 A. C. Carnall

Fluorescent imaging plays a critical role in a myriad of scientific endeavors, particularly in the biological sciences. Three-dimensional imaging of fluorescent intensity often requires serial data acquisition, that is voxel-by-voxel…

Optics · Physics 2015-10-27 Jeffrey J. Field , David G. Winters , Randy A. Bartels

Single-molecule localization microscopy (SMLM) allows reconstructing biology-relevant structures beyond the diffraction limit by detecting and localizing individual fluorophores -- fluorescent molecules stained onto the observed specimen --…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Romain Seailles , Jean-Baptiste Masson , Jean Ponce , Julien Mairal

Recent efforts to survey the numerous softwares available to perform single molecule tracking (SMT) highlighted a significant dependence of the outcomes on the specific method used, and the limitation encountered by most techniques to…

Quantitative Methods · Quantitative Biology 2019-07-26 Carmine di Rienzo , Paolo Annibale

iSpec is an integrated spectroscopic software framework suitable for the creation of spectral libraries such as the Benchmark Stars library and the determination of atmospheric parameters (i.e. effective temperature, surface gravity,…

Solar and Stellar Astrophysics · Physics 2013-12-18 S. Blanco-Cuaresma , C. Soubiran , P. Jofré , U. Heiter

This paper describes the VARTOOLS program, which is an open-source command-line utility, written in C, for analyzing astronomical time-series data, especially light curves. The program provides a general-purpose set of tools for processing…

Instrumentation and Methods for Astrophysics · Physics 2016-05-24 Joel D. Hartman , Gáspár Á Bakos

Selective plane illumination microscopy (SPIM), also known as light sheet fluorescence microscopy, provides high specificity through fluorescence labeling. However, it lacks complementary structural information from the surrounding context,…

Optics · Physics 2024-12-19 Rui Ma , Olga Lyraki , Daniel Wehner , Jochen Guck

The pioneering experiments of linear spectroscopy were performed using flames in the 1800s, but nonlinear optical measurements had to wait until lasers became available in the twentieth century. Because the nonlinear cross section of…

Quantum Physics · Physics 2016-07-13 Andreas Maser , Benjamin Gmeiner , Tobias Utikal , Stephan Götzinger , Vahid Sandoghdar

For an easy use of model order reduction techniques in applications, software solutions are needed. In this paper, we describe the MORLAB, Model Order Reduction LABoratory, toolbox as an efficient implementation of model reduction…

Mathematical Software · Computer Science 2021-09-07 Peter Benner , Steffen W. R. Werner

EUTelescope is a modular, comprehensive software framework for the reconstruction of particle trajectories recorded with beam telescopes. Its modularity allows for a flexible usage of processors each fulfilling separate tasks of the…

Spectroscopy is an indispensable tool in understanding the structures and dynamics of molecular systems. However computational modelling of spectroscopy is challenging due to the exponential scaling of computational complexity with system…

Quantum Physics · Physics 2021-06-22 Chee-Kong Lee , Chang-Yu Hsieh , Shengyu Zhang , Liang Shi

Correcting for the sky signature usually requires supplementary calibration data which are very expensive in terms of telescope time. In addition, the scheduling flexibility is restricted as these data have to be taken usually directly…

Instrumentation and Methods for Astrophysics · Physics 2014-01-31 W. Kausch , S. Noll , A. Smette , S. Kimeswenger , H. Horst , H. Sana , A. Jones , M. Barden , C. Szyszka , J. Vinther

Written in Python and utilising ParselTongue to interface with the Astronomical Image Processing System (AIPS), the e-MERLIN data reduction pipeline is intended to automate the procedures required in processing and calibrating radio…

Instrumentation and Methods for Astrophysics · Physics 2015-02-18 Megan Argo

Spectroscopy is one of the most accurate probes of the molecular world. However, predicting molecular spectra accurately is computationally difficult because of the presence of entanglement between electronic and nuclear degrees of freedom.…

In this paper we review the applicability of autofluorescent proteins for single-molecule imaging in biology. The photophysical characteristics of several mutants of the Green Fluorescent Protein (GFP) and those of DsRed are compared and…

Optics · Physics 2007-05-23 Laurent Cognet , Françoise Coussen , Daniel Choquet , Brahim Lounis

Structured illumination microscopy (SIM) uses a set of images captured with different illumination patterns to computationally reconstruct resolution beyond the diffraction limit. Here, we propose an alternative approach using a single…

Optics · Physics 2025-06-17 Ruiming Cao , Guanghan Meng , Laura Waller

We are on the verge of a revolutionary era in space exploration, thanks to advancements in telescopes such as the James Webb Space Telescope (\textit{JWST}). High-resolution, high signal-to-noise spectra from exoplanet and brown dwarf…

Instrumentation and Methods for Astrophysics · Physics 2024-07-25 Ehsan , Gharib-Nezhad , Natasha E. Batalha , Hamed Valizadegan , Miguel J. S. Martinho , Mahdi Habibi , Gopal Nookula
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