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With the rapidly increasing rate of microlensing planet detections, microlensing modeling software faces significant challenges in computation efficiency. Here, we develop the Twinkle code, an efficient and robust binary-lens modeling…

Instrumentation and Methods for Astrophysics · Physics 2025-03-18 Suwei Wang , Lile Wang , Subo Dong

The Topological Signal Processing (TSP) framework has been recently developed to analyze signals defined over simplicial complexes, i.e. topological spaces represented by finite sets of elements that are closed under inclusion of subsets…

Signal Processing · Electrical Eng. & Systems 2021-12-14 Stefania Sardellitti , Sergio Barbarossa , Lucia Testa

We derive the statistics of the signals generated by shape fluctuations of large molecules studied by feedback tracking microscopy. We account for the influence of intramolecular dynamics on the response of the tracking system, and derive a…

Optics · Physics 2015-05-13 Kevin McHale , Hideo Mabuchi

Multifocal microscopy (MFM) offers high-speed three-dimensional imaging through the simultaneous image capture from multiple focal planes. Conventional MFM systems use a fabricated grating in the emission path for a single emission…

Biological Physics · Physics 2019-07-31 M. Junaid Amin , Sabine Petry , Haw Yang , Joshua W. Shaevitz

We present a brief technical outline of the newly-formed 'Detection of Spectroscopic Differences over Time' (DS/DT) project. Our collaboration is using the individual exposures from the SDSS spectroscopic archive to produce a…

Instrumentation and Methods for Astrophysics · Physics 2015-06-03 Steven Bickerton , Carles Badenes , Thomas Hettinger , Timothy Beers , Sonya Huang

With a video data source, such as multispectral video acquired during administration of fluorescent tracers, extraction of time-resolved data typically requires the compensation of motion. While this can be done manually, which is arduous,…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 Jonathan P. Epperlein , Sergiy Zhuk

Scientists are drawn to synchrotrons and accelerator based light sources because of their brightness, coherence and flux. The rate of improvement in brightness and detector technology has outpaced Moore's law growth seen for computers,…

Orchestrating parametric fitting of multicomponent spectra at scale is an essential yet underappreciated task in high-throughput quantification of materials and chemical composition. To automate the annotation process for spectroscopic and…

Materials Science · Physics 2021-03-30 Rui Patrick Xian , Ralph Ernstorfer , Philipp Michael Pelz

This paper introduces a spectral analysis of time-seires data derived from real-time time-dependent density functional theory (TDDFT) using Singular Spectrum Analysis (SSA). TDDFT is a robust method for obtaining molecular excited states…

Computational Physics · Physics 2025-10-02 Naoki Tani , Satoru S. Kano , Yasunari Zempo

Time-lapse fluorescence microscopy (TLFM) is an important and powerful tool in synthetic biological research. Modeling TLFM experiments based on real data may enable researchers to repeat certain experiments with minor effort. This thesis…

Image and Video Processing · Electrical Eng. & Systems 2021-08-18 Christoph Reich

Hyperspectral imaging has become a significant source of valuable data for astronomers over the past decades. Current instrumental and observing time constraints allow direct acquisition of multispectral images, with high spatial but low…

Computer Vision and Pattern Recognition · Computer Science 2019-12-30 Claire Guilloteau , Thomas Oberlin , Olivier Berné , Nicolas Dobigeon

Time-frequency representations (TFRs) of signals, such as the windowed Fourier transform (WFT), wavelet transform (WT) and their synchrosqueezed variants (SWFT, SWT), provide powerful analysis tools. However, there are many important issues…

Numerical Analysis · Mathematics 2014-05-27 Dmytro Iatsenko , Peter V. E. McClintock , Aneta Stefanovska

Advances in silicon photonics have resulted in rapidly increasing complexity of integrated circuits. New methods are desirable that allow direct characterization of individual optical components in-situ, without the need for additional…

Femtosecond thermal lens spectroscopy (FTLS) is a powerful analytical tool, yet its application to complex, multi-component mixtures like fragrance accords remains limited. Here, we introduce and validate a unified metric, the Femtosecond…

Chemical Physics · Physics 2025-06-18 Rohit Goswami , Ashwini Kumar Rawat , Sonaly Goswami , Debabrata Goswami

We describe software that simulates the hardware of a scanning force microscope. The essential feature of the software is its real-time response, which is critical for mimicking the behavior of real scanning probe hardware. The simulator…

Mesoscale and Nanoscale Physics · Physics 2014-09-09 Venkat Chandrasekhar , Manan Mehta

We present a modular, extensible likelihood framework for spectroscopic inference based on synthetic model spectra. The subtraction of an imperfect model from a continuously sampled spectrum introduces covariance between adjacent datapoints…

Solar and Stellar Astrophysics · Physics 2015-10-21 Ian Czekala , Sean M. Andrews , Kaisey S. Mandel , David W. Hogg , Gregory M. Green

Scanning probe microscopy (SPM) is a valuable technique by which one can investigate the physical characteristics of the surfaces of materials. However, its widespread use is hampered by the time-consuming nature of running an experiment…

Instrumentation and Detectors · Physics 2025-09-03 Nicholas J. Sullivan , Julio J. Valdés , Kirk H. Bevan , Peter Grutter

With the advent of a new generation of telescopes (INTEGRAL, Fermi, H.E.S.S., MAGIC, VERITAS, MILAGRO) and the prospects of planned observatories such as CTA or HAWC, gamma-ray astronomy is becoming an integral part of modern astrophysical…

Instrumentation and Methods for Astrophysics · Physics 2011-10-31 Jürgen Knödlseder

We introduce the smt toolbox for Matlab. It implements optimized storage and fast arithmetics for circulant and Toeplitz matrices, and is intended to be transparent to the user and easily extensible. It also provides a set of test matrices,…

Numerical Analysis · Mathematics 2019-10-16 Michela Redivo-Zaglia , Giuseppe Rodriguez

Single-molecule sensitive microscopies and spectroscopies are transforming biophysics and materials science laboratories. Techniques such as fluorescence correlation spectroscopy (FCS) and single-molecule sensitive fluorescence resonance…