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Zeroth-order (ZO) optimization has long been favored for its biological plausibility and its capacity to handle non-differentiable objectives, yet its computational complexity has historically limited its application in deep neural…

Machine Learning · Computer Science 2026-02-12 Sansheng Cao , Zhengyu Ma , Yonghong Tian

Fine-tuning large language models (LLMs) with backpropagation\textemdash even for a subset of parameters such as LoRA\textemdash can be much more memory-consuming than inference and is often deemed impractical for resource-constrained…

Machine Learning · Computer Science 2025-10-07 Congzheng Song , Xinyu Tang

Large Language Models (LLMs) are currently pre-trained and fine-tuned on large cloud servers. The next frontier is LLM personalization, where a foundation model can be fine-tuned with user/task-specific data. Given the sensitive nature of…

Machine Learning · Computer Science 2025-09-23 Lei Gao , Amir Ziashahabi , Yue Niu , Salman Avestimehr , Murali Annavaram

Fine-tuning large language models (LLMs) poses significant memory challenges, as the back-propagation process demands extensive resources, especially with growing model sizes. Recent work, MeZO, addresses this issue using a zeroth-order…

Machine Learning · Computer Science 2024-11-19 Huaqin Zhao , Jiaxi Li , Yi Pan , Shizhe Liang , Xiaofeng Yang , Wei Liu , Xiang Li , Fei Dou , Tianming Liu , Jin Lu

Large language model (LLM) unlearning aims to surgically remove the influence of undesired data or knowledge from an existing model while preserving its utility on unrelated tasks. This paradigm has shown promise in addressing privacy and…

Machine Learning · Computer Science 2026-04-21 Yicheng Lang , Yihua Zhang , Chongyu Fan , Changsheng Wang , Jinghan Jia , Sijia Liu

On-device fine-tuning is a critical capability for edge AI systems, which must support adaptation to different agentic tasks under stringent memory constraints. Conventional backpropagation (BP)-based training requires storing layer…

Machine Learning · Computer Science 2026-05-06 Prabodh Katti , Houssem Sifaou , Sangwoo Park , Bipin Rajendran , Osvaldo Simeone

Molecule optimization is an important problem in chemical discovery and has been approached using many techniques, including generative modeling, reinforcement learning, genetic algorithms, and much more. Recent work has also applied…

Biomolecules · Quantitative Biology 2022-10-31 Elvin Lo , Pin-Yu Chen

As Large Language Models (LLMs) grow dramatically in size, there is an increasing trend in compressing and speeding up these models. Previous studies have highlighted the usefulness of gradients for importance scoring in neural network…

Computation and Language · Computer Science 2024-07-17 Hongrong Cheng , Miao Zhang , Javen Qinfeng Shi

Large language models (LLMs) are still struggling in aligning with human preference in complex tasks and scenarios. They are prone to overfit into the unexpected patterns or superficial styles in the training data. We conduct an empirical…

Computation and Language · Computer Science 2024-10-04 Zhipeng Chen , Kun Zhou , Wayne Xin Zhao , Jingyuan Wang , Ji-Rong Wen

Iterative optimization is central to modern artificial intelligence (AI) and provides a crucial framework for understanding adaptive systems. This review provides a unified perspective on this subject, bridging classic theory with neural…

Machine Learning · Computer Science 2025-10-22 Jesús García Fernández , Nasir Ahmad , Marcel van Gerven

Zeroth-order optimization (ZO) has been a powerful framework for solving black-box problems, which estimates gradients using zeroth-order data to update variables iteratively. The practical applicability of ZO critically depends on the…

Optimization and Control · Mathematics 2026-03-03 Ruiyang Jin , Yuke Zhou , Yujie Tang , Jie Song , Siyang Gao

Zeroth-order (ZO) optimization is an emerging deep neural network (DNN) training paradigm that offers computational simplicity and memory savings. However, this seemingly promising approach faces a significant and long-ignored challenge. ZO…

Machine Learning · Computer Science 2025-07-28 Qitao Tan , Sung-En Chang , Rui Xia , Huidong Ji , Chence Yang , Ci Zhang , Jun Liu , Zheng Zhan , Zhenman Fang , Zhou Zou , Yanzhi Wang , Jin Lu , Geng Yuan

Fine-tuning Large Language Models (LLMs) typically involves either full fine-tuning, which updates all model parameters, or Parameter-Efficient Fine-Tuning (PEFT), which adjusts a small subset of parameters. However, both approaches have…

Artificial Intelligence · Computer Science 2026-04-14 Shaocong Ma , Peiran Yu , Heng Huang

Full fine-tuning of Large Language Models (LLMs) is notoriously memory-intensive, primarily because conventional optimizers such as SGD or Adam assume access to exact gradients derived from cached activations. Existing solutions either…

Machine Learning · Computer Science 2025-10-28 Jing Yang , Kaitong Cai , Yijia Fan , Yufeng Yang , Keze Wang

Zeroth-Order optimization presents a promising memory-efficient paradigm for fine-tuning Large Language Models by relying solely on forward passes. However, its practical adoption is severely constrained by slow wall-clock convergence and…

Machine Learning · Computer Science 2026-04-21 Fei Wang , Li Shen , Liang Ding , Chao Xue , Ye Liu , Changxing Ding

Federated Learning (FL) offers a promising pathway for collaboratively fine-tuning Large Language Models (LLMs) at the edge; however, this paradigm faces a critical bottleneck: the prohibitive communication and memory overheads incurred by…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-15 Zhijie Cai , Yuhao Zheng , Haolong Chen , Dongzhu Liu , Bin Wang , Guangxu Zhu

One of the major bottlenecks for deploying popular first-order differentially private (DP) machine learning algorithms (e.g., DP-SGD) lies in their high computation and memory cost, despite the existence of optimized implementations.…

Machine Learning · Computer Science 2026-01-14 Xuchen Gong , Tian Li

Fine-tuning large models on edge devices is severely hindered by the memory-intensive backpropagation (BP) in standard frameworks like federated learning and split learning. While substituting BP with zeroth-order optimization can…

Machine Learning · Computer Science 2026-05-28 Qiyuan Chen , Xian Wu , Yi Wang , Xianhao Chen

First-order algorithms have been popular for solving convex and non-convex optimization problems. A key assumption for the majority of these algorithms is that the gradient of the objective function is globally Lipschitz continuous, but…

Optimization and Control · Mathematics 2024-02-07 Junyu Zhang , Mingyi Hong

Large language models (LLMs) have demonstrated remarkable performance due to their large parameter counts and extensive training data. However, their scale leads to significant memory bottlenecks during training, especially when using…

Machine Learning · Computer Science 2026-05-14 Ziqing Wen , Jiahuan Wang , Ping Luo , Dongsheng Li , Tao Sun