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In this numerical study areas of the carotid bifurcation and of a distal stenosis in the internal carotid artery are closely observed to evaluate the patient's current risks of ischemic stroke. An indicator for the vessel wall defects is…

Analysis of PDEs · Mathematics 2022-09-23 Kevin Richter , Tristan Probst , Anna Hundertmark , Pepe Eulzer , Kai Lawonn

Methods of Computational Fluid Dynamics are applied to simulate pulsatile blood flow in human vessels and in the aortic arch. The non-Newtonian behaviour of the human blood is investigated in simple vessels of actual size. A detailed…

Computational Physics · Physics 2008-02-19 Renat A. Sultanov , Dennis Guster , Brent Engelbrekt , Richard Blankenbecler

Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with…

Fluid Dynamics · Physics 2025-02-03 Ayodele Oyejide , Oluwatosin Abodunrin , Ebenezer Ige , Adetokunbo Awonusi

The analysis of quantitative hemodynamics and luminal pressure may add valuable information to aid treatment strategies and prognosis for aortic dissections. This work directly compared in vitro 4D-flow magnetic resonance imaging (MRI),…

We investigate the rheological characteristics of human blood plasma in shear and elongational flows. While we can confirm a Newtonian behavior in shear flow within experimental resolution, we find a viscoelastic behavior of blood plasma in…

Biological Physics · Physics 2013-02-19 M. Brust , C. Schaefer , L. Pan , M. Garcia , P. E. Arratia , C Wagner

Computational fluid dynamics (CFD) studies of left atrial flows have reached a sophisticated level, e.g., revealing plausible relationships between hemodynamics and stresses with atrial fibrillation. However, little focus has been on…

Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…

Computer Vision and Pattern Recognition · Computer Science 2022-04-07 Derek Long , Cameron McMurdo , Edward Ferdian , Charlene A. Mauger , David Marlevi , Alistair A. Young , Martyn P. Nash

Previous studies suggest that the behaviour of impacting blood is similar to that of a Newtonian fluid, which has a shear viscosity equivalent to that of blood at high shear rates. To understand this important fact, we conducted comparative…

Fluid Dynamics · Physics 2024-12-10 Yuto Yokoyama , Akane Tanaka , Yoshiyuki Tagawa

There is currently limited understanding of the role played by haemodynamic forces on the processes governing vascular development. One of many obstacles to be overcome is being able to measure those forces, at the required resolution…

Stent implantation in coronary bifurcations presents unique challenges and currently there is no universally accepted stent deployment approach. Despite clinical and computational studies, to date, the effect of each stent implantation…

Atherosclerotic lesions within carotid and cerebral vessels are likely to influence hemodynamics and manifest into vascular pathologies, including Alzheimers Disease and ischemic stroke. Hemodynamics are influenced by changes in luminal…

Tissues and Organs · Quantitative Biology 2023-03-24 Jennifer Buoncore , Alexis Sobecki , Brian Lee Beatty

The non-linear behavior of human erythrocytes subjected to shear stress was analyzed using data series from the Erythrocyte Rheometer and a theoretical model was developed. Linear behavior was eliminated by means of a slot filter and a…

Cell Behavior · Quantitative Biology 2018-10-19 Horacio Castellini , Bibiana Riquelme

Atherosclerosis is a disease caused due to formation of plaque into the artery. Increase in plaque affects the wall shear stress. The present study is performed to calculate wall shear stress in different geometries of stenosed carotid…

Medical Physics · Physics 2017-06-05 Ruchika Bhatia , Sharda Vashisth , Renu Saini

The rheology of suspensions showing discontinuous shear thickening (DST) is well documented in conventional rheometer with rotating tools, but their study in capillary flow is still lacking. We present results obtained in a homemade…

Materials Science · Physics 2021-11-29 Georges Bossis , Yan Grasselli , Olga Volkova

Cardiovascular diseases, specifically cerebral aneurysms, represent a major cause of morbidity and mortality, having a significant impact on the cost and overall status of health care. In the present work, we employ a haemorheological blood…

Fluid Dynamics · Physics 2023-10-23 Kamyar Behrouzi , Zahra Khodabakhshi Fard , Azadeh Jafari , Robert G. Owens

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

Leveraging big data for patient care is promising in many medical fields such as cardiovascular health. For example, hemodynamic biomarkers like wall shear stress could be assessed from patient-specific medical images via machine learning…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Julian Suk , Jolanda J. Wentzel , Patryk Rygiel , Joost Daemen , Daniel Rueckert , Jelmer M. Wolterink

Cardiovascular surgeries and mechanical circulatory support devices create non-physiological blood flow conditions that can be detrimental, especially for pediatric patients. A source of complications is mechanical red blood cell (RBC)…

Fluid Dynamics · Physics 2025-10-27 Saba Mansour , Emily Logan , James F. Antaki , Mahdi Esmaily

The aim of this paper is to present a modeling for the rheological behavior of simple liquids as a function of the amplitude of the imposed shear stress or strain. The elastic mode theory (Ref. 6) is first generalized to take into account…

Soft Condensed Matter · Physics 2023-02-14 Frédéric Aitken , Ferdinand Volino

For high-fidelity predictions of turbulent flows in complex practical engineering problems, the Wall-Modeled (WM) Large-Eddy Simulation (LES) has aroused great interest. In the present study, we prove that the conventional Wall-Stress…

Fluid Dynamics · Physics 2025-11-12 Mohammad Taghvaei , Ehsan Amani