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Pulsatile flow through compressed or defective blood vessels is a topic of fundamental importance in hemodynamics, particularly in cardiovascular research. This study examines flow dynamics within a tube with a bipolar cross section,…

Medical Physics · Physics 2025-03-04 Doyeol , Ahn

A discrete boundary-sensitive Hodge decomposition is proposed as a central tool for the analysis of wall shear stress (WSS) vector fields in aortic blood flows. The method is based on novel results for the smooth and discrete…

Quantitative Methods · Quantitative Biology 2018-11-22 Faniry H. Razafindrazaka , Pavlo Yevtushenko , Konstantin Poelke , Konrad Polthier , Leonid Goubergrits

The dynamics of a quasi two-dimensional isotropic droplet in a cholesteric liquid crystal medium under symmetric shear flow is studied by lattice Boltzmann simulations. We consider a geometry in which the flow direction is along the axis of…

Soft Condensed Matter · Physics 2018-07-13 Federico Fadda , Giuseppe Gonnella , Antonio Lamura , Enzo Orlandini , Adriano Tiribocchi

We study the finite-shear-rate rheology of disordered solids by means of molecular dynamics simulations in two dimensions. By systematically varying the damping magnitude $\zeta$ in the low-temperature limit, we identify two well defined…

Soft Condensed Matter · Physics 2016-02-10 Alexandre Nicolas , Jean-Louis Barrat , Jörg Rottler

Of concern in the paper is a generalized theoretical study of the non-Newtonian characteristics of peristaltic flow of blood through micro-vessels, e.g. arterioles. The vessel is considered to be of variable cross-section and blood to be a…

Fluid Dynamics · Physics 2013-08-19 S. Maiti , J. C. Misra

We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…

Fluid Dynamics · Physics 2008-11-11 Renat A. Sultanov , Dennis Guster

Considerations on implementation of the stress-strain constitutive relations applied in Computational Fluid dynamics (CFD) simulation of cardiovascular flows have been addressed extensively in the literature. However, the matter is yet…

Quantitative Methods · Quantitative Biology 2016-08-16 S. M. Javid Mahmoudzadeh Akherat

Blood viscosity decreases with shear stress, a property essential for an efficient perfusion of the vascular tree. Shear-thinning is intimately related to the dynamics and mutual interactions of red blood cells (RBCs), the major…

In this work, we study non-Newtonian fluid flow in heterogeneous porous media. We are interested in fluids presenting a specific change in rheology: Newtonian below a certain shear rate and power law above. Since porous media generally…

Fluid Dynamics · Physics 2022-03-28 Laurent Talon

Intracranial aneurysms remain a major cause of neurological morbidity and mortality worldwide, where rupture risk is tightly coupled to local hemodynamics particularly wall shear stress and oscillatory shear index. Conventional…

This work aims at identifying and quantifying uncertainties related to elastic and viscoelastic parameters, which characterize the arterial wall behavior, in one-dimensional modeling of the human arterial hemodynamics. The chosen uncertain…

Fluid Dynamics · Physics 2021-02-12 Giulia Bertaglia , Valerio Caleffi , Lorenzo Pareschi , Alessandro Valiani

We consider active suspensions in the isotropic phase subjected to a shear flow. Using a set of extended hydrodynamic equations we derive a variety of {\em analytical} expressions for rheological quantities such as shear viscosity and…

Soft Condensed Matter · Physics 2015-05-20 Sebastian Heidenreich , Siegfried Hess , Sabine H. L. Klapp

Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…

Numerical Analysis · Mathematics 2024-11-28 Kabir Bakhshaei , Sajad Salavatidezfouli , Giovanni Stabile , Gianluigi Rozza

Three intra-aortic blood pumps were evaluated and compared using CFD simulations. The aim of this study is to evaluate the hemodynamic performance and calculate the hemolytic potential of the pumps. The flow fields generated by the pumps…

Medical Physics · Physics 2026-03-31 Osman Aycan , Yeojin Park , Lyes Kadem

The development and progression of abdominal aortic aneurysms (AAA) are related to complex flow patterns and wall-shear-driven mechanobiological stimuli, yet the quantitative relationship between aneurysmal geometry and hemodynamics remains…

Blood is a complex suspension that demonstrates several non-Newtonian rheological characteristics such as deformation-rate dependency, viscoelasticity and yield stress. In this paper we outline some issues related to the non-Newtonian…

Fluid Dynamics · Physics 2014-06-10 Taha Sochi

An erythrocytes sedimentation rate (ESR) measures how fast a blood sample sediments along a test tube in one hour in a clinical laboratory. Since elevated level of ESR is associated with inflammatory diseases, ESR is one of the routine…

Biological Physics · Physics 2019-07-30 Mesfin Asfaw Taye

Optimal hematocrit $H_o$ maximizes oxygen transport. In healthy humans, the average hematocrit $H$ is in the range of 40-45$\%$, but it can significantly change in blood pathologies such as severe anemia (low $H$) and polycythemia (high…

Coronary anatomy governs local haemodynamics associated with atherosclerotic development, progression and ultimately adverse clinical outcomes. However, lack of large sample size studies and methods to link adverse haemodynamics to…

Medical Physics · Physics 2024-01-24 R. Gharleghi , M. Zhang , C. Shen , M. Webster , C. Ellis , S. Beier

We measure the dynamical mechanical properties of human red blood cells. Single cell response is measured with optical tweezers. We investigate both the stress relaxation following a fast deformation, and the effect of varying the strain…

Soft Condensed Matter · Physics 2009-11-13 Young-Zoon Yoon , Jurij Kotar , Gilwon Yoon , Pietro Cicuta