English

Study of non-linear viscoelastic behavior of the human red blood cell

Cell Behavior 2018-10-19 v1 Soft Condensed Matter Biological Physics

Abstract

The non-linear behavior of human erythrocytes subjected to shear stress was analyzed using data series from the Erythrocyte Rheometer and a theoretical model was developed. Linear behavior was eliminated by means of a slot filter and a sixth order Savisky-Golay filter was applied to the resulting time series that allows the elimination of any possible white noise in the data. A fast Fourier transform was performed on the processed data, which resulted in a series of frequency dominant peaks. Results suggest the presence of a non-linear quadratic term in the Kelvin-Voigt phenomenological model. The correlation dimension studied through recurrence quantification analysis gave C2=2.58. Results suggest that the underlying dynamics is the same in each RBC sample corresponding to healthy donors.

Keywords

Cite

@article{arxiv.1810.07760,
  title  = {Study of non-linear viscoelastic behavior of the human red blood cell},
  author = {Horacio Castellini and Bibiana Riquelme},
  journal= {arXiv preprint arXiv:1810.07760},
  year   = {2018}
}