Related papers: Enhancing Hemodynamic Parameter Estimations: Nonli…
This study employs extensive three-dimensional direct numerical simulations (DNS) to investigate the influence of blood non-Newtonian behaviors on the hemodynamics around a bileaflet mechanical heart valve under both steady inflow and…
This study investigates the effects of geometric model reduction on blood flow simulations in the patient-specific descending aorta, followed by speed-accuracy trade-off analysis using 3D simulations. We demonstrate how wall shear stresses…
Arterial wall shear stress (WSS) parameters are widely used for prediction of the initiation and development of atherosclerosis and arterial pathologies. Traditional clinical evaluation of arterial condition relies on correlations of WSS…
This study investigates the hemodynamic behavior of blood flow in the aortic arch across anemic, diabetic, and healthy conditions using computational fluid dynamics (CFD) simulations with a non-Newtonian Carreau viscosity model. Velocity…
Perturbations to the homeostatic distribution of mechanical forces exerted by blood on the endothelial layer have been correlated with vascular pathologies including intracranial aneurysms and atherosclerosis. Recent computational work…
This study investigates the influence of aneurysm evolution on hemodynamic characteristics within the sac region. Using computational fluid dynamics (CFD), blood flow through the parent vessel and aneurysm sac was analyzed to assess the…
The influence of blood rheology on hemodynamic parameters is investigated using Computational Fluid Dynamics on blood flow through the human carotid artery. We performed three-dimensional modeling and simulation to study blood flow through…
Wall shear stress (WSS) has been suggested as a potential biomarker in various cardiovascular diseases and it can be estimated from phase-contrast Magnetic Resonance Imaging (PC-MRI) velocity measurements. We present a new parametric…
Understanding the complex interplay between morphologic and hemodynamic features in aortic dissection is critical for risk stratification and for the development of individualized therapy. This work evaluates the effects of entry and exit…
In this work, we investigate the effects of stent indentation on hemodynamic indicators in stented coronary arteries. Our aim is to assess in-silico risk factors for in-stent restenosis (ISR) and thrombosis after stent implantation. The…
Typical approaches to patient-specific hemodynamic studies of cerebral aneurysms use image based computational fluid dynamics (CFD) and seek to statistically correlate parameters such as wall shear stress (WSS) and oscillatory shear index…
We propose a hemodynamic reduced-order model bridging macroscopic and meso-scopic blood flow circulation scales from arteries to capillaries. In silico tree like vascular geometries, mathematically described by graphs, are synthetically…
Computational fluid dynamics (CFD) is a valuable asset for patient-specific cardiovascular-disease diagnosis and prognosis, but its high computational demands hamper its adoption in practice. Machine-learning methods that estimate blood…
The geometry of blood vessels strongly affects hemostasis and thrombosis through red blood cell (RBC) dynamics and platelet margination. Growing platelet aggregates, in turn, reshape the local vessel wall topography, leading to a strongly…
Abdominal aortic aneurysms (AAAs) are pathologic dilatations of the abdominal aorta posing a high fatality risk upon rupture. Studying AAA progression and rupture risk often involves in-silico blood flow modelling with computational fluid…
In this work we present a simple qualitative model to describe shear rheological behavior of the twist-bend nematic liquid crystals. We find that at relatively low shear rate the effective viscosity decreases with the shear rate manifesting…
Shear stress plays an important role in the creation and evolution of atherosclerosis. An key element for in-vivo measurements and extrapolations is the dependence of shear stress on body mass. In the case of a Poiseuille modeling of the…
The role of Helical Flow (HF) in human coronary arteries remains uncertain, yet its understanding promises unprecedented insights into atherosclerotic processes. In this study, we investigated the effects of HF and key haemodynamic…
Cerebral aneurysms are pathological dilations of intracranial arteries that can rupture with devastating consequences, including subarachnoid hemorrhage, stroke, and death. Accumulating evidence indicates that local hemodynamic forces play…
The link between atherosclerosis and blood flow-induced haemodynamic luminal shear stresses is well established. However, this understanding has not been translated into clinical practice because of the interdependent effects of the complex…