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Large Language Models (LLMs) have demonstrated impressive capabilities across various specialist domains and have been integrated into high-stakes areas such as medicine. However, as existing medical-related benchmarks rarely stress-test…

Computation and Language · Computer Science 2026-03-26 Lin Yang , Yuancheng Yang , Xu Wang , Changkun Liu , Haihua Yang

As large language models (LLMs) gain traction in healthcare, concerns about their susceptibility to demographic biases are growing. We introduce {DiversityMedQA}, a novel benchmark designed to assess LLM responses to medical queries across…

Computation and Language · Computer Science 2024-12-09 Rajat Rawat , Hudson McBride , Dhiyaan Nirmal , Rajarshi Ghosh , Jong Moon , Dhruv Alamuri , Sean O'Brien , Kevin Zhu

Large language models (LLMs) are entering clinician workflows, yet evaluations rarely measure how clinician reasoning shapes model behavior during clinical interactions. We combined 61 New England Journal of Medicine Case Records with 92…

Large Language Models (LLMs) have made substantial progress in the past several months, shattering state-of-the-art benchmarks in many domains. This paper investigates LLMs' behavior with respect to gender stereotypes, a known issue for…

Computation and Language · Computer Science 2023-08-30 Hadas Kotek , Rikker Dockum , David Q. Sun

Large language models (LLMs) have the potential to transform medicine, but real-world clinical scenarios contain extraneous information that can hinder performance. The rise of assistive technologies like ambient dictation, which…

Computation and Language · Computer Science 2025-04-03 Krithik Vishwanath , Anton Alyakin , Daniel Alexander Alber , Jin Vivian Lee , Douglas Kondziolka , Eric Karl Oermann

Large Language Models (LLMs) have exhibited impressive natural language processing capabilities but often perpetuate social biases inherent in their training data. To address this, we introduce MultiLingual Augmented Bias Testing…

Computation and Language · Computer Science 2025-04-29 Alessio Buscemi , Cédric Lothritz , Sergio Morales , Marcos Gomez-Vazquez , Robert Clarisó , Jordi Cabot , German Castignani

In this study, we present MedS-Bench, a comprehensive benchmark designed to evaluate the performance of large language models (LLMs) in clinical contexts. Unlike existing benchmarks that focus on multiple-choice question answering,…

Computation and Language · Computer Science 2024-09-06 Chaoyi Wu , Pengcheng Qiu , Jinxin Liu , Hongfei Gu , Na Li , Ya Zhang , Yanfeng Wang , Weidi Xie

Large language models (LLMs), such as ChatGPT, have received substantial attention due to their capabilities for understanding and generating human language. While there has been a burgeoning trend in research focusing on the employment of…

In contemporary society, the issue of psychological health has become increasingly prominent, characterized by the diversification, complexity, and universality of mental disorders. Cognitive Behavioral Therapy (CBT), currently the most…

Computation and Language · Computer Science 2024-07-26 Hao Shen , Zihan Li , Minqiang Yang , Minghui Ni , Yongfeng Tao , Zhengyang Yu , Weihao Zheng , Chen Xu , Bin Hu

Large language models (LLMs) have been applied to tasks in healthcare, ranging from medical exam questions to responding to patient questions. With increasing institutional partnerships between companies producing LLMs and healthcare…

Computation and Language · Computer Science 2024-04-10 Jesutofunmi A. Omiye , Haiwen Gui , Shawheen J. Rezaei , James Zou , Roxana Daneshjou

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Large Language Models (LLMs) such as ChatGPT demonstrate significant potential in the medical domain and are often evaluated using multiple-choice questions (MCQs) modeled on exams like the USMLE. However, such benchmarks may overestimate…

Computation and Language · Computer Science 2025-08-22 Maxime Griot , Jean Vanderdonckt , Demet Yuksel , Coralie Hemptinne

Large Language Models (LLMs) are known to exhibit social, demographic, and gender biases, often as a consequence of the data on which they are trained. In this work, we adopt a mechanistic interpretability approach to analyze how such…

Computation and Language · Computer Science 2025-06-09 Bhavik Chandna , Zubair Bashir , Procheta Sen

Several recent works seek to adapt general-purpose large language models (LLMs) and vision-language models (VLMs) for medical applications through continued pretraining on publicly available biomedical corpora. These works typically claim…

Computation and Language · Computer Science 2025-07-01 Daniel P. Jeong , Pranav Mani , Saurabh Garg , Zachary C. Lipton , Michael Oberst

Large language models (LLMs) are increasingly explored for clinical decision support, yet most evaluations are conducted in English, leaving their reliability in other languages uncertain. Here we evaluate the impact of prompting language…

Computation and Language · Computer Science 2026-05-20 Adrien Bazoge , Josselin Corvellec , Sofiane Djillali Sid-Ahmed , Pierre-Antoine Gourraud

Existing studies on bias mitigation methods for large language models (LLMs) use diverse baselines and metrics to evaluate debiasing performance, leading to inconsistent comparisons among them. Moreover, their evaluations are mostly based…

Computation and Language · Computer Science 2026-02-17 Xin Xu , Xunzhi He , Churan Zhi , Ruizhe Chen , Julian McAuley , Zexue He

Large language models (LLMs) like GPT-4 show potential for scaling motivational interviewing (MI) in addiction care, but require systematic evaluation of therapeutic capabilities. We present a computational framework assessing…

Computation and Language · Computer Science 2025-05-26 Yinghui Huang , Yuxuan Jiang , Hui Liu , Yixin Cai , Weiqing Li , Xiangen Hu

Large Language Models (LLMs) have shown remarkable capabilities in a multitude of Natural Language Processing (NLP) tasks. However, these models are still not immune to limitations such as social biases, especially gender bias. This work…

Computation and Language · Computer Science 2024-10-15 Divij Bajaj , Yuanyuan Lei , Jonathan Tong , Ruihong Huang

Cancer clinical trials often face challenges in recruitment and engagement due to a lack of participant-facing informational and educational resources. This study investigated the potential of Large Language Models (LLMs), specifically…

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

Computation and Language · Computer Science 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo