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The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Large language models (LLMs) used in medical applications are known to be prone to exhibiting biased and unfair patterns. Prior to deploying these in clinical decision-making, it is crucial to identify such bias patterns to enable effective…

Artificial Intelligence · Computer Science 2025-12-23 Farzana Islam Adiba , Rahmatollah Beheshti

This study evaluates the capacity of large language models (LLMs) to generate structured clinical consultation templates for electronic consultation. Using 145 expert-crafted templates developed and routinely used by Stanford's eConsult…

Large Language Models are cognitively biased judges. Large Language Models (LLMs) have recently been shown to be effective as automatic evaluators with simple prompting and in-context learning. In this work, we assemble 15 LLMs of four…

Computation and Language · Computer Science 2024-09-26 Ryan Koo , Minhwa Lee , Vipul Raheja , Jong Inn Park , Zae Myung Kim , Dongyeop Kang

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

Computation and Language · Computer Science 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Current ophthalmology clinical workflows are plagued by over-referrals, long waits, and complex and heterogeneous medical records. Large language models (LLMs) present a promising solution to automate various procedures such as triaging,…

The modeling of bio-molecular system across molecular scales remains a central challenge in scientific research. Large language models (LLMs) are increasingly applied to bio-molecular discovery, yet systematic evaluation across multi-scale…

Machine Learning · Computer Science 2026-04-07 Yaxin Xu , Yue Zhou , Tianyu Zhao , Fengwei An , Zhixiang Ren

As large language models transition from text-based interfaces to audio interactions in clinical settings, they might introduce new vulnerabilities through paralinguistic cues in audio. We evaluated these models on 170 clinical cases, each…

Computation and Language · Computer Science 2025-11-11 Zhi Rui Tam , Yun-Nung Chen

Multilingual large language models (LLMs) have minimized the fluency gap between languages. This advancement, however, exposes models to the risk of biased behavior, as knowledge and norms may propagate across languages. In this work, we…

Computation and Language · Computer Science 2026-04-22 Guy Mor-Lan , Omer Goldman , Matan Eyal , Adi Mayrav Gilady , Sivan Eiger , Idan Szpektor , Avinatan Hassidim , Yossi Matias , Reut Tsarfaty

Medical reasoning in large language models (LLMs) aims to emulate clinicians' diagnostic thinking, but current benchmarks such as MedQA-USMLE, MedMCQA, and PubMedQA often mix reasoning with factual recall. We address this by separating 11…

Large language models like GPT-3.5-turbo and GPT-4 hold promise for healthcare professionals, but they may inadvertently inherit biases during their training, potentially affecting their utility in medical applications. Despite few attempts…

Computation and Language · Computer Science 2024-09-18 Yifan Yang , Xiaoyu Liu , Qiao Jin , Furong Huang , Zhiyong Lu

Large Language Models have been tested on medical student-level questions, but their performance in specialized fields like Critical Care Medicine (CCM) is less explored. This study evaluated Meta-Llama 3.1 models (8B and 70B parameters) on…

Computation and Language · Computer Science 2025-09-25 Mahmoud Alwakeel , Aditya Nagori , An-Kwok Ian Wong , Neal Chaisson , Vijay Krishnamoorthy , Rishikesan Kamaleswaran

Recent research has shown that hallucinations, omissions, and biases are prevalent in everyday use-cases of LLMs. However, chatbots used in medical contexts must provide consistent advice in situations where non-medical factors are…

Computation and Language · Computer Science 2025-11-05 Jonathan Liu , Haoling Qiu , Jonathan Lasko , Damianos Karakos , Mahsa Yarmohammadi , Mark Dredze

Large Language Models (LLMs) have demonstrated remarkable abilities in text comprehension and logical reasoning, indicating that the text representations learned by LLMs can facilitate their language processing capabilities. In…

Artificial Intelligence · Computer Science 2025-01-16 Yuqi Ren , Renren Jin , Tongxuan Zhang , Deyi Xiong

Detecting cognitive biases in large language models (LLMs) is a fascinating task that aims to probe the existing cognitive biases within these models. Current methods for detecting cognitive biases in language models generally suffer from…

Computation and Language · Computer Science 2024-10-08 Zhentao Xie , Jiabao Zhao , Yilei Wang , Jinxin Shi , Yanhong Bai , Xingjiao Wu , Liang He

Cognitive biases are systematic deviations in thinking that lead to irrational judgments and problematic decision-making, extensively studied across various fields. Recently, large language models (LLMs) have shown advanced understanding…

Computation and Language · Computer Science 2024-10-10 Nuo Chen , Jiqun Liu , Xiaoyu Dong , Qijiong Liu , Tetsuya Sakai , Xiao-Ming Wu

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

Human-Computer Interaction · Computer Science 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

Large Language Models (LLMs) are increasingly being used to simulate human-like decision making in agent-based financial market models (ABMs). As models become more powerful and accessible, researchers can now incorporate individual LLM…

Machine Learning · Computer Science 2025-01-29 Alicia Vidler , Toby Walsh

In this work, we designed unbiased prompts to systematically evaluate the psychological safety of large language models (LLMs). First, we tested five different LLMs by using two personality tests: Short Dark Triad (SD-3) and Big Five…

Computation and Language · Computer Science 2024-03-01 Xingxuan Li , Yutong Li , Lin Qiu , Shafiq Joty , Lidong Bing

Large language models (LLMs) have shown remarkable adaptability to diverse tasks, by leveraging context prompts containing instructions, or minimal input-output examples. However, recent work revealed they also exhibit label bias -- an…

Computation and Language · Computer Science 2024-05-07 Yuval Reif , Roy Schwartz