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To obtain high-quality positron emission tomography (PET) while minimizing radiation exposure, a range of methods have been designed to reconstruct standard-dose PET (SPET) from corresponding low-dose PET (LPET) images. However, most…

Image and Video Processing · Electrical Eng. & Systems 2024-04-11 Yuchen Fei , Yanmei Luo , Yan Wang , Jiaqi Cui , Yuanyuan Xu , Jiliu Zhou , Dinggang Shen

Cone beam computed tomography (CBCT) for breast imaging has potential to replace conventional mammograms. However, concerns over dose and image quality prevent CBBCT systems from the clinical trial phase to next stage. The time of flight…

Medical Physics · Physics 2021-02-01 Ignacio O. Romero , Changqing Li

The novel whole-body PET system based on plastic scintillators is developed by the {J-PET} Collaboration. It consists of plastic scintillator strips arranged axially in the form of a cylinder, allowing the cost-effective construction of the…

X-ray computed tomography (CT) is one of widely used diagnostic tools for medical and dental tomographic imaging of the human body. However, the standard filtered backprojection reconstruction method requires the complete knowledge of the…

Numerical Analysis · Mathematics 2016-02-24 Jae Kyu Choi , Bin Dong , Xiaoqun Zhang

Low-dose Computed Tomography is a common issue in reality. Current reduction, sparse sampling and limited-view scanning can all cause it. Between them, limited-view CT is general in the industry due to inevitable mechanical and physical…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Ken Deng , Chang Sun , Yitong Liu , Hongwen Yang

Computed Tomography (CT) reconstruction is a fundamental component to a wide variety of applications ranging from security, to healthcare. The classical techniques require measuring projections, called sinograms, from a full 180$^\circ$…

Computer Vision and Pattern Recognition · Computer Science 2018-07-12 Rushil Anirudh , Hyojin Kim , Jayaraman J. Thiagarajan , K. Aditya Mohan , Kyle Champley , Timo Bremer

Objective: To develop and validate an independent Monet Carlo dose calculation engine to support for software verification of treatment planning systems and quality assurance workflow. Method: GATE Monte Carlo toolkit was employed to…

Medical Physics · Physics 2021-07-27 A. Asadi , A. Akhavanallaf , S. A. Hosseini , N. vosoughi , H. Zaidi

Time-of-flight positron emission tomography (TOF-PET) detectors exhibiting multiple coincidence time resolution (CTR) components, such as those induced by the mixing of Cherenkov and scintillation photons, have attracted increasing…

Medical Physics · Physics 2026-05-29 Kibo Ote , Fumio Hashimoto , Yuya Onishi , Ryosuke Ota , Maxime Toussaint , Francis Loignon-Houle

The purpose of this study was to show how advanced concepts of compact, lossless and "Time Of Flight" (TOF) capable electronics similar to those foreseen for the LHC and ILC experiments could be fairly and easily transferred to the medical…

Instrumentation and Detectors · Physics 2009-08-03 P. -E. Vert , J. Lecoq , G. Montarou , N. Pauna , B. Joly , M. Boutemeur , H. Mathez , R. Gaglione , P. Le Dû

Monte Carlo simulation is an essential tool in emission tomography that can assist in the design of new medical imaging devices, the optimization of acquisition protocols, and the development or assessment of image reconstruction algorithms…

Monte Carlo simulations are increasingly used in scintigraphic imaging to model imaging systems and to develop and assess tomographic reconstruction algorithms and correction methods for improved image quantitation. GATE (GEANT 4…

Instrumentation and Detectors · Physics 2009-11-10 D. Lazaro , I. Buvat , G. Loudos , D. Strul , G. Santin , N. Giokaris , D. Donnarieix , L. Maigne , V. Spanoudaki , S. Styliaris , S. Staelens , V. Breton

Statistical iterative reconstruction is expected to improve the image quality of megavoltage computed tomography (MVCT). However, one of the challenges of iterative reconstruction is its large computational cost. The purpose of this work is…

Single Photon Emission Computed Tomography (SPECT) is a non-invasive imaging modality, frequently used in myocardial perfusion imaging. The biggest challenges facing the majority of clinical SPECT systems are low sensitivity, poor…

Medical Physics · Physics 2021-03-30 Narayan Bhusal

LAFOV PET/CT has the potential to unlock new applications such as ultra-low dose PET/CT imaging, multiplexed imaging, for biomarker development and for faster AI-driven reconstruction, but further work is required before these can be…

Parallel hole collimators which are currently routinely used in SPECT imaging were designed a few decades ago, when filtered backprojection (FBP) was used for tomographic reconstruction. Statistical reconstruction methods with precise…

Medical Physics · Physics 2018-07-02 Krzysztof Kacperski , Dominika Świtlik , Jakub Pietrzak

As a sensitive functional imaging technique, positron emission tomography (PET) plays a critical role in early disease diagnosis. However, obtaining a high-quality PET image requires injecting a sufficient dose (standard dose) of…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Caiwen Jiang , Mianxin Liu , Kaicong Sun , Dinggang Shen

Positron Emission Tomography (PET) is an important molecular imaging tool widely used in medicine. Traditional PET systems rely on complete detector rings for full angular coverage and reliable data collection. However, incomplete-ring PET…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Yeqi Fang , Rong Zhou

To acquire high-quality positron emission tomography (PET) images while reducing the radiation tracer dose, numerous efforts have been devoted to reconstructing standard-dose PET (SPET) images from low-dose PET (LPET). However, the success…

Image and Video Processing · Electrical Eng. & Systems 2024-07-31 Jiaqi Cui , Pinxian Zeng , Yuanyuan Xu , Xi Wu , Jiliu Zhou , Yan Wang

We developed a positron emission tomography (PET) system for multiple-isotope imaging. Our PET system, named multiple-isotope PET (MI-PET), can distinguish between different tracer nuclides using coincidence measurement of prompt…

Two algorithms for solving misalignment issues in penalized PET/CT reconstruction using anatomical priors are proposed. Both approaches are based on a recently published joint motion estimation and image reconstruction method. The first…