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Single-Photon Emission Computed Tomography (SPECT) is widely applied for the diagnosis of coronary artery diseases. Low-dose (LD) SPECT aims to minimize radiation exposure but leads to increased image noise. Limited-view (LV) SPECT, such as…

Image and Video Processing · Electrical Eng. & Systems 2024-01-25 Xiongchao Chen , Bo Zhou , Xueqi Guo , Huidong Xie , Qiong Liu , James S. Duncan , Albert J. Sinusas , Chi Liu

Depth-of-interaction (DOI) encoding is an effective strategy for reducing parallax error and preserving spatial resolution in positron emission tomography (PET), particularly in compact small-animal scanners. To enable efficient…

Medical Physics · Physics 2026-03-10 Satzhan Sitmukhambetov , Junwei Du , Mingwu Jin , Yujie Chi

Positron emission tomographs (PET) do not measure an image directly. Instead, they measure at the boundary of the field-of-view (FOV) of PET tomograph a sinogram that consists of measurements of the sums of all the counts along the lines…

Currently inorganic scintillator detectors are used in all commercial Time of Flight Positron Emission Tomograph (TOF-PET) devices. The J-PET collaboration investigates a possibility of construction of a PET scanner from plastic…

In this study we evaluated the task-based image quality of a low contrast clinical task for the abdomen protocol (e.g., pancreatic tumour) of three different CT vendors, exploiting three model-based iterative reconstruction (MBIR) levels.…

Medical Physics · Physics 2023-01-23 G. Muti , S. Riga , L. Berta , D. Curto , C. De Mattia , M. Felisi , F. Rizzetto , A. Torresin , A. Vanzulli , P. E. Colombo

In this work, image analysis techniques used in astrophysics to detect low-contrast signals have been adapted in the processing of Computed Tomography (CT) images, combining Centroidal Voronoi Tessellation (CVT) and machine learning…

Medical Physics · Physics 2025-03-11 Lorenzo Lasagni

A novel reconstruction method is introduced for the severely ill-posed inverse problem of limited-angle tomography. It is well known that, depending on the available measurement, angles specify a subset of the wavefront set of the unknown…

Image and Video Processing · Electrical Eng. & Systems 2023-10-26 Elli Karvonen , Matti Lassas , Pekka Pankka , Samuli Siltanen

Image reconstruction in Single Photon Emission Computed Tomography (SPECT) is affected by physical effects such as photon attenuation, Compton scatter and detector response. These effects can be compensated for by modeling the corresponding…

Medical Physics · Physics 2009-11-11 Z. El Bitar , D. Lazaro , C. Coello , V. Breton , D. Hill , I. Buvat

Positron Emission Mammography (PEM) imaging systems with the ability in detection of millimeter-sized tumors were developed in recent years. And some of them have been well used in clinical applications. In consideration of biopsy…

Medical Physics · Physics 2016-08-03 Xiao-Yue Gu , Wei Zhou , Lin Li , Peng-Fei Yin , Lei-Min Shang , Ming-Kai Yun , Zhen-Rui Lu , Xian-Chao Huang , Long Wei

The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment…

Recently, an ultra-low-cost linear scan based tomography architecture was proposed by our team. Similar to linear tomosynthesis, the source and detector are translated in opposite directions and the data acquisition system targets on a…

Medical Physics · Physics 2016-10-21 Weiwen Wu , Hengyong Yu , Shaoyu Wang , Fenglin Liu

Purpose: We develop an iterative image-reconstruction algorithm for application to low-intensity computed tomography (CT) projection data, which is based on constrained, total-variation (TV) minimization. The algorithm design focuses on…

Medical Physics · Physics 2015-05-20 Emil Y. Sidky , Yuval Duchin , Christer Ullberg , Xiaochuan Pan

Differentiable rendering has been widely adopted in computer graphics as a powerful approach to inverse problems, enabling efficient gradient-based optimization by differentiating the image formation process with respect to millions of…

PET is an established medical diagnostic imaging method. Continuous improvements are aimed at refining image reconstruction, reducing the amount of radioactive tracer and combining with targeted therapy. TOF-PET provides the localization of…

Medical Physics · Physics 2021-11-17 Tomasz Matulewicz

Computed tomography (CT) reconstruction from X-ray projections acquired within a limited angle range is challenging, especially when the angle range is extremely small. Both analytical and iterative models need more projections for…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Ce Wang , Haimiao Zhang , Qian Li , Kun Shang , Yuanyuan Lyu , Bin Dong , S. Kevin Zhou

In positron emission tomography (PET), it is indispensable to perform attenuation correction in order to obtain the quantitatively accurate activity map (tracer distribution) in the body. Generally, this is carried out based on the…

Medical Physics · Physics 2025-10-16 Liyang Hu , Chong Chen

Recently, linear computed tomography (LCT) systems have actively attracted attention. To weaken projection truncation and image the region of interest (ROI) for LCT, the backprojection filtration (BPF) algorithm is an effective solution.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Zhisheng Wang , Zihan Deng , Fenglin Liu , Yixing Huang , Haijun Yu , Junning Cui

The Learned Primal Dual (LPD) method has shown promising results in various tomographic reconstruction modalities, particularly under challenging acquisition restrictions such as limited viewing angles or a limited number of views. We…

Image and Video Processing · Electrical Eng. & Systems 2026-01-01 Sean Breckling , Matthew Swan , Keith D. Tan , Derek Wingard , Brandon Baldonado , Yoohwan Kim , Ju-Yeon Jo , Evan Scott , Jordan Pillow

We present a method and preliminary results of the image reconstruction in the Jagiellonian PET tomograph. Using GATE (Geant4 Application for Tomographic Emission), interactions of the 511 keV photons with a cylindrical detector were…