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Parkinsons Disease (PD) is a neurodegenerative disorder resulting in motor deficits due to advancing degeneration of dopaminergic neurons. PD patients report experiencing tremor, rigidity, visual impairment, bradykinesia, and several…

Computer Vision and Pattern Recognition · Computer Science 2023-04-05 Krish Desai

Background and Objective: Parkinson's disease (PD) is the second most common progressive neurological condition after Alzheimer's, characterized by motor and non-motor symptoms. Developing a method to diagnose the condition in its beginning…

Machine Learning · Computer Science 2022-10-05 Paria Ghaheri , Hamid Nasiri , Ahmadreza Shateri , Arman Homafar

Perceptual voice quality dimensions describe key characteristics of atypical speech and other speech modulations. Here we develop and evaluate voice quality models for seven voice and speech dimensions (intelligibility, imprecise…

We present a framework to recognize Parkinson's disease (PD) through an English pangram utterance speech collected using a web application from diverse recording settings and environments, including participants' homes. Our dataset includes…

Severity assessment of Parkinson's disease (PD) using wearable sensors offers an effective, objective basis for clinical management. However, general-purpose time series models often lack pathological specificity in feature extraction,…

Machine Learning · Computer Science 2025-10-14 Weiming Zhao , Xulong Wang , Jun Qi , Yun Yang , Po Yang

Generative spoken language models produce speech in a wide range of voices, prosody, and recording conditions, seemingly approaching the diversity of natural speech. However, the extent to which generated speech is acoustically diverse…

Audio and Speech Processing · Electrical Eng. & Systems 2025-03-12 Matthieu Futeral , Andrea Agostinelli , Marco Tagliasacchi , Neil Zeghidour , Eugene Kharitonov

Parkinsons disease is the second most prevalent neurodegenerative disorder with over ten million active cases worldwide and one million new diagnoses per year. Detecting and subsequently diagnosing the disease is challenging because of…

Computation and Language · Computer Science 2024-04-09 Jonathan Crawford

Parkinson's disease is easy to diagnose when it is advanced, but it is very difficult to diagnose in its early stages. Early diagnosis is essential to be able to treat the symptoms. It impacts on daily activities and reduces the quality of…

In this study we focus on the diagnosis of Parkinson's Disease (PD) based on electroencephalogram (EEG) signals. We propose a new approach inspired by the functioning of the brain that uses the dynamics, frequency and temporal content of…

Systems and Control · Electrical Eng. & Systems 2023-03-31 Houssem Meghnoudj , Bogdan Robu , Mazen Alamir

The diverse perceptual consequences of hearing loss severely impede speech communication, but standard clinical audiometry, which is focused on threshold-based frequency sensitivity, does not adequately capture deficits in frequency and…

Audio and Speech Processing · Electrical Eng. & Systems 2025-07-31 Xiajie Zhou , Candy Olivia Mawalim , Masashi Unoki

We present a diachronic acoustic analysis of the voice of 1023 speakers from French media archives. The speakers are spread across 32 categories based on four periods (years 1955/56, 1975/76, 1995/96, 2015/16), four age groups (20-35;…

Audio and Speech Processing · Electrical Eng. & Systems 2024-04-26 Albert Rilliard , David Doukhan , Rémi Uro , Simon Devauchelle

Parkinson's disease (PD) is one of the most common neurodegenerative disorder. PD telemonitoring emerges as a novel assessment modality enabling self-administered at-home tests of Unified Parkinson's Disease Rating Scale (UPDRS) scores,…

Machine Learning · Computer Science 2025-10-03 Ziming Tang , Chengbin Hou , Tianyu Zhang , Bangxu Tian , Jinbao Wang , Hairong Lv

Speech impairments are prevalent biomarkers for Parkinson's Disease (PD), motivating the development of diagnostic techniques using speech data for clinical applications. Although deep acoustic features have shown promise for PD…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-01 Emmy Postma , Cristian Tejedor-Garcia

Chronic obstructive pulmonary disease (COPD) causes lung inflammation and airflow blockage leading to a variety of respiratory symptoms; it is also a leading cause of death and affects millions of individuals around the world. Patients…

Parkinsons Disease (PD) is a progressive neurological disorder that primarily affects motor functions and can lead to mild cognitive impairment (MCI) and dementia in its advanced stages. With approximately 10 million people diagnosed…

Image and Video Processing · Electrical Eng. & Systems 2025-05-02 Abu Saleh Musa Miah , taro Suzuki , Jungpil Shin

Deep-Brain Stimulation (DBS) is a therapy used in conjunction with medication to help alleviate the motor symptoms of Parkinson's Disease (PD). However, the monitoring and adjustment of DBS settings is tedious and expensive, requiring long…

Neurons and Cognition · Quantitative Biology 2019-12-03 Huy Phi , Sanjeev Janarthanan , Larry Zhang , Reza Hosseini Ghomi

Recent works in pathological speech analysis have increasingly relied on powerful self-supervised speech representations, leading to promising results. However, the complex, black-box nature of these embeddings and the limited research on…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 David Gimeno-Gómez , Catarina Botelho , Anna Pompili , Alberto Abad , Carlos-D. Martínez-Hinarejos

Pitch and Formant frequencies are important features in speech processing applications. The period of the vocal cord's output for vowels is known as the pitch or the fundamental frequency, and formant frequencies are essentially resonance…

Audio and Speech Processing · Electrical Eng. & Systems 2022-09-09 Seyedamiryousef Hosseini Goki , Mahdieh Ghazvini , Sajad Hamzenejadi

Accurate diagnosis of Parkinson disease, especially in its early stages, can be a challenging task. The application of machine learning techniques helps improve the diagnostic accuracy of Parkinson disease detection but only few studies…

Machine Learning · Computer Science 2024-12-25 Majid Ali , Hina Shakir , Asia Samreen , Sohaib Ahmed

Parkinson's disease (PD) is a debilitating neurological disorder that necessitates precise and early diagnosis for effective patient care. This study aims to develop a diagnostic model capable of achieving both high accuracy and minimizing…

Machine Learning · Computer Science 2024-01-30 Seyedeh Zahra Seyedi Hosseininian , Ahmadreza Tajari , Mohsen Ghalehnoie , Alireza Alfi