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Large audio and language models have recently demonstrated zero-shot reasoning capabilities across various domains. However, it remains unclear how the form of audio input, whether handcrafted acoustic features extracted from speech or the…

Sound · Computer Science 2026-05-26 Muhammad Ashad Kabir , Sirajam Munira

PPINtonus is a system for the early detection of Parkinson's Disease (PD) utilizing deep-learning tonal analysis, providing a cost-effective and accessible alternative to traditional neurological examinations. Partnering with the…

Audio and Speech Processing · Electrical Eng. & Systems 2024-06-06 Varun Reddy

Imprecise vowel articulation can be observed in people with Parkinson's disease (PD). Acoustic features measuring vowel articulation have been demonstrated to be effective indicators of PD in its assessment. Standard clinical vowel…

Audio and Speech Processing · Electrical Eng. & Systems 2021-08-18 Yuanyuan Liu , Nelly Penttilä , Tiina Ihalainen , Juulia Lintula , Rachel Convey , Okko Räsänen

Early-stage Parkinson's disease (EarlyPD) detection from speech is clinically meaningful yet underexplored, and published results are hard to compare because studies differ in datasets, languages, tasks, evaluation protocols, and EarlyPD…

Audio and Speech Processing · Electrical Eng. & Systems 2026-05-15 Terry Yi Zhong , Cristian Tejedor-Garcia , Khiet P. Truong , Janna Maas , Louis ten Bosch , Bastiaan R. Bloem

Parkinson's disease (PD), a neurodegenerative disorder, often manifests as speech and voice dysfunction. While utilizing voice data for PD detection has great potential in clinical applications, the widely used deep learning models…

Machine Learning · Computer Science 2023-09-26 Yicheng Wang , Xiaotian Han , Leisheng Yu , Na Zou

Parkinson's Disease (PD) is a progressive neurodegenerative disorder that significantly impacts both motor and non-motor functions, including speech. Early and accurate recognition of PD through speech analysis can greatly enhance patient…

Numerical Analysis · Mathematics 2024-07-24 Niloofar Fadavi , Nazanin Fadavi

More than 90% of the Parkinson Disease (PD) patients suffer from vocal disorders. Speech impairment is already indicator of PD. This study focuses on PD diagnosis through voiceprint features. In this paper, a method based on Deep Neural…

Sound · Computer Science 2018-12-18 Zhijing Xu , Juan Wang , Ying Zhang , Xiangjian He

Parkinson's Disease (PD) is a neurodegenerative disorder characterized by motor symptoms, including altered voice production in the early stages. Early diagnosis is crucial not only to improve PD patients' quality of life but also to…

Audio and Speech Processing · Electrical Eng. & Systems 2025-01-15 Maksim Siniukov , Ellie Xing , Sanaz Attaripour Isfahani , Mohammad Soleymani

The speech of people with Parkinson's Disease (PD) has been shown to hold important clues about the presence and progression of the disease. We investigate the factors based on which humans experts make judgments of the presence of disease…

We investigate the potential association between leucine-rich repeat kinase 2 (LRRK2) mutations and voice. Sustained phonations ('aaah' sounds) were recorded from 7 individuals with LRRK2-associated Parkinson's disease (PD), 17 participants…

Objective: The aim of this study is to develop a smartphone-based high-frequency remote monitoring platform, assess its feasibility for remote monitoring of symptoms in Parkinson's disease, and demonstrate the value of data collected using…

Computers and Society · Computer Science 2016-01-06 Andong Zhan , Max A. Little , Denzil A. Harris , Solomon O. Abiola , E. Ray Dorsey , Suchi Saria , Andreas Terzis

Up to 90 % of patients with Parkinson's disease (PD) suffer from hypokinetic dysarthria (HD). In this work, we analysed the power of conventional speech features quantifying imprecise articulation, dysprosody, speech dysfluency and speech…

Goal: Numerous studies had successfully differentiated normal and abnormal voice samples. Nevertheless, further classification had rarely been attempted. This study proposes a novel approach, using continuous Mandarin speech instead of a…

Audio and Speech Processing · Electrical Eng. & Systems 2022-02-23 Syu-Siang Wang , Chi-Te Wang , Chih-Chung Lai , Yu Tsao , Shih-Hau Fang

The performance of voice-based Parkinson's disease (PD) detection systems degrades when there is an acoustic mismatch between training and operating conditions caused mainly by degradation in test signals. In this paper, we address this…

Audio and Speech Processing · Electrical Eng. & Systems 2019-06-03 Amir Hossein Poorjam , Mathew Shaji Kavalekalam , Liming Shi , Yordan P. Raykov , Jesper Rindom Jensen , Max A. Little , Mads Græsbøll Christensen

Speech disorders often occur at the early stage of Parkinson's disease (PD). The speech impairments could be indicators of the disorder for early diagnosis, while motor symptoms are not obvious. In this study, we constructed a new speech…

Audio and Speech Processing · Electrical Eng. & Systems 2021-06-01 Hao Fang , Chen Gong , Chen Zhang , Yanan Sui , Luming Li

Auditory feedback plays an essential role in the regulation of the fundamental frequency of voiced sounds. The fundamental frequency also responds to auditory stimulation other than the speaker's voice. We propose to use this response of…

This paper considers a representation learning strategy to model speech signals from patients with Parkinson's disease and cleft lip and palate. In particular, it compares different parametrized representation types such as wideband and…

Audio and Speech Processing · Electrical Eng. & Systems 2022-09-20 Gabriel Figueiredo Miller , Juan Camilo Vásquez-Correa , Juan Rafael Orozco-Arroyave , Elmar Nöth

Parkinson's disease (PD) is a prevalent neurodegenerative disorder known for its impact on motor neurons, causing symptoms like tremors, stiffness, and gait difficulties. This study explores the potential of vocal feature alterations in PD…

The screening of Parkinson's Disease (PD) through speech is hindered by a notable lack of publicly available datasets in different languages. This fact limits the reproducibility and further exploration of existing research. To address this…

Speech impairments in Parkinson's disease (PD) provide significant early indicators for diagnosis. While models for speech-based PD detection have shown strong performance, their interpretability remains underexplored. This study…

Sound · Computer Science 2024-11-14 Eleonora Mancini , Francesco Paissan , Paolo Torroni , Mirco Ravanelli , Cem Subakan